Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Christopher K. Breuer"'
Autor:
John M. Kelly, MD, Zinan Hu, BS, Felipe Takaesu, BS, Tatsuya Watanabe, MD, PhD, Judd Storrs, PhD, Benjamin Blais, MD, Satoshi Yuhara, MD, Adrienne Morrison, BA, Kirsten Nelson, BA, Anudari Ulziibayar, MD, Eric Heuer, BA, Cole Anderson, BS, Michael Jimenez, BA, Joseph Leland, BA, Raphael Malbrue, DVM, Carmen Arsuaga-Zorrilla, DVM, MS, Laurie Goodchild, DVM, Aymen Naguib, MD, Christopher McKee, MD, Jordan Varner, BA, Cameron DeShetler, BS, Joshua Spiess, BA, Andrew Harrison, BA, Brian Boe, MD, Aimee K. Armstrong, MD, Arash Salavitabar, MD, Kan Hor, MD, Rajesh Krishnamurthy, MD, Andrew R. Yates, MD, Toshiharu Shinoka, MD, PhD, Sergio A. Carrillo, MD, Michael E. Davis, PhD, Alison L. Marsden, PhD, Christopher K. Breuer, MD
Publikováno v:
JTCVS Open, Vol 21, Iss , Pp 268-278 (2024)
Objectives: Our goal was to conduct a hemodynamic analysis of a novel animal model of Fontan physiology. Poor late-term outcomes in Fontan patients are believed to arise from Fontan-induced hemodynamics, but the mechanisms remain poorly understood. R
Externí odkaz:
https://doaj.org/article/0dd841fd94ee42ae8ce14d5209eb6770
Autor:
Mackenzie E. Turner, Kevin M. Blum, Tatsuya Watanabe, Erica L. Schwarz, Mahboubeh Nabavinia, Joseph T. Leland, Delaney J. Villarreal, William E. Schwartzman, Ting-Heng Chou, Peter B. Baker, Goki Matsumura, Rajesh Krishnamurthy, Andrew R. Yates, Kan N. Hor, Jay D. Humphrey, Alison L. Marsden, Mitchel R. Stacy, Toshiharu Shinoka, Christopher K. Breuer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Advancements in congenital heart surgery have heightened the importance of durable biomaterials for adult survivors. Dystrophic calcification poses a significant risk to the long-term viability of prosthetic biomaterials in these procedures.
Externí odkaz:
https://doaj.org/article/f668f876930840c49404946d6ccd249c
Autor:
Mackenzie E. Turner, Jingru Che, Gabriel J. M. Mirhaidari, Catherine C. Kennedy, Kevin M. Blum, Sahana Rajesh, Jacob C. Zbinden, Christopher K. Breuer, Cameron A. Best, Jenny C. Barker
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Lysosomes and lysosome related organelles (LROs) are dynamic organelles at the intersection of various pathways involved in maintaining cellular hemostasis and regulating cellular functions. Vesicle trafficking of lysosomes and LROs are critical to m
Externí odkaz:
https://doaj.org/article/00d98c9b7f134f2b8324161ef0851867
Autor:
Kevin M. Nash, PhD, Brian A. Boe, MD, Sergio A. Carrillo, MD, Andrew Harrison, AS, ARRT, Ryuma Iwaki, MD, John Kelly, MD, Robert D. Kirkton, PhD, Ramkumar Krishnamurthy, PhD, Jeffrey H. Lawson, MD, PhD, Yuichi Matsuzaki, MD, PhD, Heather L. Prichard, PhD, Kejal Shah, MD, Toshiharu Shinoka, MD, PhD, Christopher K. Breuer, MD
Publikováno v:
JTCVS Open, Vol 15, Iss , Pp 433-445 (2023)
Objectives: Palliative treatment of cyanotic congenital heart disease (CCHD) uses systemic-to-pulmonary conduits, often a modified Blalock–Taussig–Thomas shunt (mBTTs). Expanded polytetrafluoroethylene (ePTFE) mBTTs have associated risks for thro
Externí odkaz:
https://doaj.org/article/dbfdc050eeff4efa8d573ed68bec9a99
Autor:
Xinzeng Feng, Yifei Liu, David Kamensky, David W. McComb, Christopher K. Breuer, Michael S. Sacks
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Genetically modified mouse models provide a versatile and efficient platform to extend our understanding of the underlying disease processes and evaluate potential treatments for congenital heart valve diseases. However, applications have be
Externí odkaz:
https://doaj.org/article/cc32eab84353481db45cc39c93d1189d
Autor:
Zheng Hong Tan, Sayali Dharmadhikari, Lumei Liu, Jane Yu, Kimberly M. Shontz, Jacob T. Stack, Christopher K. Breuer, Susan D. Reynolds, Tendy Chiang
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Extensive tracheal injury or disease can be life-threatening but there is currently no standard of care. Regenerative medicine offers a potential solution to long-segment tracheal defects through the creation of scaffolds that support the ge
Externí odkaz:
https://doaj.org/article/c0db940d1af44a219fa5135946c3d2e3
Autor:
Ting‐Heng Chou, Mahboubeh Nabavinia, Nguyen K. Tram, Eleanor T. Rimmerman, Surina Patel, Kumudha Narayana Musini, Susan Natalie Eisert, Tatiana Wolfe, Molly K. Wynveen, Yuichi Matsuzaki, Takahiro Kitsuka, Ryuma Iwaki, Sarah A. Janse, Adam J. Bobbey, Christopher K. Breuer, Laurie Goodchild, Raphael Malbrue, Toshiharu Shinoka, Said A. Atway, Michael R. Go, Mitchel R. Stacy
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 4 (2024)
Background Perfusion deficits contribute to symptom severity, morbidity, and death in peripheral artery disease (PAD); however, no standard method for quantifying absolute measures of skeletal muscle perfusion exists. This study sought to preclinical
Externí odkaz:
https://doaj.org/article/9c09f89c1b3a49bd8ce96425446ee59e
Autor:
Kevin M. Blum, Gabriel J. M. Mirhaidari, Jacob C. Zbinden, Christopher K. Breuer, Jenny C. Barker
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 10, Pp 638-647 (2022)
Abstract Capsular contracture as a result of the foreign body response (FBR) is a common issue after implant‐based breast reconstruction, affecting up to 20% of patients. New evidence suggests that tamoxifen may mitigate the FBR. C57BL/6 female mic
Externí odkaz:
https://doaj.org/article/c1aad9e3adaf4411831362b34253688e
Autor:
Kevin M. Blum, Jacob C. Zbinden, Abhay B. Ramachandra, Stephanie E. Lindsey, Jason M. Szafron, James W. Reinhardt, Megan Heitkemper, Cameron A. Best, Gabriel J. M. Mirhaidari, Yu-Chun Chang, Anudari Ulziibayar, John Kelly, Kejal V. Shah, Joseph D. Drews, Jason Zakko, Shinka Miyamoto, Yuichi Matsuzaki, Ryuma Iwaki, Hira Ahmad, Robbie Daulton, Drew Musgrave, Matthew G. Wiet, Eric Heuer, Emily Lawson, Erica Schwarz, Michael R. McDermott, Rajesh Krishnamurthy, Ramkumar Krishnamurthy, Kan Hor, Aimee K. Armstrong, Brian A. Boe, Darren P. Berman, Aaron J. Trask, Jay D. Humphrey, Alison L. Marsden, Toshiharu Shinoka, Christopher K. Breuer
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-21 (2022)
Plain language summary Surgery to correct defects in the heart that are present at birth sometimes requires the use of artificial blood vessels called vascular grafts. Tissue-engineered vascular grafts (TEVGs) are scaffolds seeded with cells that can
Externí odkaz:
https://doaj.org/article/cf83b6fbad07439fa512a6b4905d7efd
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Murine animal models are an established standard in translational research and provides a potential platform for studying heart valve disease. To date, studies on heart valve disease using murine models have been hindered by a lack of approp
Externí odkaz:
https://doaj.org/article/2622d5b5e0b140f4aadaecd9ce8af04e