Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Christopher K Raymond"'
Autor:
Christopher K Raymond
Publikováno v:
BioTechniques, Vol 67, Iss 4, Pp 188-191 (2019)
Genomic analysis of circulating, cell-free DNA (cfDNA) is being used extensively for molecular diagnostics. Many approaches rely on the construction of cfDNA genomic libraries, targeted retrieval of specific genomic regions and analysis by next-gener
Externí odkaz:
https://doaj.org/article/7f938ce23745430db192ebfe144ccca0
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0231854 (2020)
UltraPrep is an open-source, two-step method for purification of cell-free DNA that entails extraction of total DNA followed by size-selective enrichment of the smaller fragments that are characteristic of DNA originating from fragmentation between n
Externí odkaz:
https://doaj.org/article/477d9f3568eb439ca5a43c412f04d23e
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176241 (2017)
The breadth of diagnostic procedures that utilize cell free DNA (cfDNA) from human plasma has increased dramatically in recent years. Here, we confirm that tumor-derived cfDNA fragments are similar in size distribution to cfDNA derived from normal ti
Externí odkaz:
https://doaj.org/article/c758e04ff4c54233b4b375590ffe19ef
Autor:
John C Castle, Christopher D Armour, Martin Löwer, David Haynor, Matthew Biery, Heather Bouzek, Ronghua Chen, Stuart Jackson, Jason M Johnson, Carol A Rohl, Christopher K Raymond
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11779 (2010)
Non-coding RNAs (ncRNAs) are an essential class of molecular species that have been difficult to monitor on high throughput platforms due to frequent lack of polyadenylation. Using a polyadenylation-neutral amplification protocol and next-generation
Externí odkaz:
https://doaj.org/article/6236f85931c74602abb7b0894b8a483a
Autor:
John C Castle, Yoshikazu Hara, Christopher K Raymond, Philip Garrett-Engele, Kenji Ohwaki, Zhengyan Kan, Jun Kusunoki, Jason M Johnson
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4369 (2009)
Acetyl-CoA carboxylases ACC1 and ACC2 catalyze the carboxylation of acetyl-CoA to malonyl-CoA, regulating fatty-acid synthesis and oxidation, and are potential targets for treatment of metabolic syndrome. Expression of ACC1 in rodent lipogenic tissue
Externí odkaz:
https://doaj.org/article/4970341b1eab4e9283fe1ceb74f92e09
Autor:
Marc Ladanyi, Sutirtha Datta, Dan DiPasquo, Alex Makhnin, Paul K. Paik, Alexander Drilon, Jamie E. Chaft, Mackenzie L. Myers, David R. Jones, Mark G. Kris, Andres Martinez, Jeong O Jeon, Bob T. Li, Charles M. Rudin, Adrian Lee, Dennis Stephens, Nidhi Tandon, Nick Pavlakis, Maria E. Arcila, Gregory J. Riely, James M. Isbell, Connie I. Diakos, Ysleni Leger, Joshua K. Sabari, Laetitia Borsu, Jennifer Hernandez, Matthew D. Hellmann, Michael Offin, Mark Li, Tristan Shaffer, Kavita Garg, Andy Ni, Helena A. Yu, Samantha Henderson, Lee P. Lim, Andreas Rimner, Christopher K. Raymond, Valerie W. Rusch, Stephen Clarke
Publikováno v:
JNCI: Journal of the National Cancer Institute. 111:575-583
BACKGROUND: Liquid biopsy for plasma circulating tumor DNA (ctDNA) next-generation sequencing (NGS) is commercially available and increasingly adopted in clinical practice despite a paucity of prospective data to support its use. METHODS: Patients wi
UltraPrep is an open-source, two-step method for purification of cell-free DNA that entails extraction of total DNA followed by size-selective enrichment of the smaller fragments that are characteristic of DNA originating from fragmentation between n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4295e0b1bfcc91a658d852bf95064a1a
Autor:
Karinna Almodovar, Catherine B. Meador, Yu Shyr, Lee P. Lim, Wade T. Iams, Christopher K. Raymond, Zhiguo Zhao, Yingjun Yan, Sally York, Jennifer Hernandez, Christine M. Lovly, Leora Horn, Heidi Chen
Publikováno v:
Journal of Thoracic Oncology. 13:112-123
Introduction Patients with small cell lung cancer (SCLC) have a poor prognosis and limited treatment options. Since access to longitudinal tumor samples is very limited in patients with this disease, we chose to focus our studies on the characterizat
Autor:
Karinna Almodovar, Lee P. Lim, Christopher K. Raymond, Cindy L. Vnencak-Jones, Wade T. Iams, Jennifer Hernandez, Christine M. Lovly, Kathryn E. Beckermann, Leora Horn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924a6bbf0cb2dec1569ed4530031328c
https://europepmc.org/articles/PMC6382512/
https://europepmc.org/articles/PMC6382512/
Autor:
Matthew Biery, Marissa Vignali, Wonjong Moon, Patrick E. Duffy, Tomas Babak, Robert Morrison, Christopher D. Armour, Christopher K. Raymond, Jingyang Chen, Heather Bouzek, Michal Fried, John C. Castle
Publikováno v:
Journal of Clinical Investigation. 121:1119-1129
Malaria caused by Plasmodium falciparum results in approximately 1 million annual deaths worldwide, with young children and pregnant mothers at highest risk. Disease severity might be related to parasite virulence factors, but expression profiling st