Zobrazeno 1 - 10
of 370
pro vyhledávání: '"Christopher K, Tuggle"'
Autor:
Beulah Esther Rani Samuel, Fabian E. Diaz, Teresia W. Maina, Ryan J. Corbett, Christopher K. Tuggle, Jodi L. McGill
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The Bacillus Calmette Guerin (BCG) vaccine has been shown to induce non-specific protection against diseases other than tuberculosis in vaccinated individuals, attributed to the induction of trained immunity. We have previously demonstrated that BCG
Externí odkaz:
https://doaj.org/article/4ebee13de8f843b6925f3560249c7aa7
Autor:
Christopher K. Tuggle, Jennifer L. Clarke, Brenda M. Murdoch, Eric Lyons, Nicole M. Scott, Bedrich Beneš, Jacqueline D. Campbell, Henri Chung, Courtney L. Daigle, Sruti Das Choudhury, Jack C. M. Dekkers, Joao R. R. Dórea, David S. Ertl, Max Feldman, Breno O. Fragomeni, Janet E. Fulton, Carmela R. Guadagno, Darren E. Hagen, Andrew S. Hess, Luke M. Kramer, Carolyn J. Lawrence-Dill, Alexander E. Lipka, Thomas Lübberstedt, Fiona M. McCarthy, Stephanie D. McKay, Seth C. Murray, Penny K. Riggs, Troy N. Rowan, Moira J. Sheehan, Juan P. Steibel, Addie M. Thompson, Kara J. Thornton, Curtis P. Van Tassell, Patrick S. Schnable
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Dramatic improvements in measuring genetic variation across agriculturally relevant populations (genomics) must be matched by improvements in identifying and measuring relevant trait variation in such populations across many environments (ph
Externí odkaz:
https://doaj.org/article/16775bc608354ceabfd4ba8fddc9415e
Autor:
Ryan J. Corbett, Andrea M. Luttman, Juber Herrera-Uribe, Haibo Liu, Nancy E. Raney, Jenna M. Grabowski, Crystal L. Loving, Christopher K. Tuggle, Catherine W. Ernst
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Genetics studies in the porcine immune system have enhanced selection practices for disease resistance phenotypes and increased the efficacy of porcine models in biomedical research; however limited functional annotation of the po
Externí odkaz:
https://doaj.org/article/d2f9f8bbb9724885a18519f66f754cbe
Autor:
Juber Herrera-Uribe, Kyu-Sang Lim, Kristen A. Byrne, Lance Daharsh, Haibo Liu, Ryan J. Corbett, Gianna Marco, Martine Schroyen, James E. Koltes, Crystal L. Loving, Christopher K. Tuggle
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Neutrophils are vital components of the immune system for limiting the invasion and proliferation of pathogens in the body. Surprisingly, the functional annotation of porcine neutrophils is still limited. The transcriptomic and epigenetic assessment
Externí odkaz:
https://doaj.org/article/cedb7edc21234d88b20d51e19310d1be
Autor:
Christopher K. Tuggle, Jennifer Clarke, Jack C. M. Dekkers, David Ertl, Carolyn J. Lawrence-Dill, Eric Lyons, Brenda M. Murdoch, Nicole M. Scott, Patrick S. Schnable
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-11 (2022)
Externí odkaz:
https://doaj.org/article/9639d32910d6461eb1ecb69c85fb1cc7
Autor:
Zhangyuan Pan, Yuelin Yao, Hongwei Yin, Zexi Cai, Ying Wang, Lijing Bai, Colin Kern, Michelle Halstead, Ganrea Chanthavixay, Nares Trakooljul, Klaus Wimmers, Goutam Sahana, Guosheng Su, Mogens Sandø Lund, Merete Fredholm, Peter Karlskov-Mortensen, Catherine W. Ernst, Pablo Ross, Christopher K. Tuggle, Lingzhao Fang, Huaijun Zhou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Annotating functional elements of the genome helps the interpretation of genetic variation. Here, the authors compile functional genomics data for the pig genome over 14 tissues with 15 different chromatin states, integrate the data with WGS and GWAS
Externí odkaz:
https://doaj.org/article/9d93bfd836f04f2482675331b406ee47
Autor:
Kyu-Sang Lim, Jian Cheng, Austin Putz, Qian Dong, Xuechun Bai, Hamid Beiki, Christopher K. Tuggle, Michael K. Dyck, Pig Gen Canada, Frederic Fortin, John C. S. Harding, Graham S. Plastow, Jack C. M. Dekkers
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-18 (2021)
Abstract Background Disease resilience, which is the ability of an animal to maintain performance under disease, is important for pigs in commercial herds, where they are exposed to various pathogens. Our objective was to investigate population-level
Externí odkaz:
https://doaj.org/article/2449f19d95254b758d4cbe04ec4eee8a
Autor:
Qian Dong, Joan K. Lunney, Kyu-Sang Lim, Yet Nguyen, Andrew S. Hess, Hamid Beiki, Raymond R. R. Rowland, Kristen Walker, James M. Reecy, Christopher K. Tuggle, Jack C. M. Dekkers
Publikováno v:
BMC Veterinary Research, Vol 17, Iss 1, Pp 1-21 (2021)
Abstract Background Porcine reproductive and respiratory syndrome (PRRS) is a threat to pig production worldwide. Our objective was to understand mechanisms of persistence of PRRS virus (PRRSV) in tonsil. Transcriptome data from tonsil samples collec
Externí odkaz:
https://doaj.org/article/72186250470e43f3804021d4b3346867
Autor:
Carolyn J. Lawrence-Dill, Robyn L. Allscheid, Albert Boaitey, Todd Bauman, Edward S. Buckler, Jennifer L. Clarke, Christopher Cullis, Jack Dekkers, Cassandra J. Dorius, Shawn F. Dorius, David Ertl, Matthew Homann, Guiping Hu, Mary Losch, Eric Lyons, Brenda Murdoch, Zahra-Katy Navabi, Somashekhar Punnuri, Fahad Rafiq, James M. Reecy, Patrick S. Schnable, Nicole M. Scott, Moira Sheehan, Xavier Sirault, Margaret Staton, Christopher K. Tuggle, Alison Van Eenennaam, Rachael Voas
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/7d921451f70e47edb4598c8b477a9ea1
Autor:
Michelle M. Halstead, Colin Kern, Perot Saelao, Ying Wang, Ganrea Chanthavixay, Juan F. Medrano, Alison L. Van Eenennaam, Ian Korf, Christopher K. Tuggle, Catherine W. Ernst, Huaijun Zhou, Pablo J. Ross
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background Although considerable progress has been made towards annotating the noncoding portion of the human and mouse genomes, regulatory elements in other species, such as livestock, remain poorly characterized. This lack of functional an
Externí odkaz:
https://doaj.org/article/021ea6b0f94e46c5a3998910d08cf005