Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christopher John Squire"'
Autor:
Christopher John Squire, Simone Tomasi, Julie Reilly, Kevin William Leslie, Denise Watt, Lianne Frodsham, David J. Klauber, Michael David Golden, Claire S. MacLeod, Martin N. Kenworthy, Andrew S. Wells, Rebecca E. Meadows, Susan Hard, Keith R. Mulholland
Publikováno v:
Organic Process Research & Development. 17:1123-1130
ω-Transaminase enzyme chemistry provides an excellent methodology to build synthetically useful chiral amines from their corresponding ketones. An application of this methodology, providing a long-term commercial manufacturing route to a JAK2 kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebc65a2e80bdcc5e235569e3cc72e9bc
https://doi.org/10.1021/op400133d
https://doi.org/10.1021/op400133d
Autor:
Harrie Straatman, Christopher John Squire, Michael David Golden, Daniel Mink, Andrew S. Wells, Rebecca E. Meadows, Elise Meulenbroeks, Martin Schürmann, Oliver May, Keith R. Mulholland, Hans Kierkels
Publikováno v:
Organic Process Research & Development. 17:1117-1122
Screening of 60 transaminases using three different amine donors found that the ω-transaminase from Vibrio fluvialis together with (S)-α-methylbenzylamine to be the most promising combination to deliver the desired (S)-1-(5-fluoropyrimidin-2-yl)-et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00c36999ee6d956fdeaa05c32807b55e
https://doi.org/10.1021/op400131h
https://doi.org/10.1021/op400131h
Autor:
Daniel Mink, Christopher John Squire, Andrew S. Wells, Rebecca E. Meadows, Michael David Golden, Hans Kierkels, Oliver May, Keith R. Mulholland, Harrie Straatman, Elise Meulenbroeks, Martin Schürmann
Publikováno v:
Practical Methods for Biocatalysis and Biotransformations 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7746755d41c98226d9b75c7c6331d69a
https://doi.org/10.1002/9781118697856.ch09
https://doi.org/10.1002/9781118697856.ch09
