Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christopher J. Tracy"'
Autor:
Connor M. Kean, Christopher J. Tracy, Apratim Mitra, Beenish Rahat, Matthew T. Van Winkle, Claudia M. Gebert, Jacob A. Noeker, Anne L. Calof, Arthur D. Lander, Judith A. Kassis, Karl Pfeifer
Publikováno v:
Science Advances. 8
Cohesin rings interact with DNA and modulate the expression of thousands of genes. NIPBL loads cohesin onto chromosomes, and WAPL takes it off. Haploinsufficiency for NIPBL causes a developmental disorder, Cornelia de Lange syndrome (CdLS), that is m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b293d8a6b083eb1a83207657f877d9f
https://doi.org/10.1126/sciadv.add4136
https://doi.org/10.1126/sciadv.add4136
Autor:
Connor M, Kean, Christopher J, Tracy, Apratim, Mitra, Beenish, Rahat, Matthew T, Van Winkle, Claudia M, Gebert, Jacob A, Noeker, Anne L, Calof, Arthur D, Lander, Judith A, Kassis, Karl, Pfeifer
Publikováno v:
Science advances. 8(48)
Cohesin rings interact with DNA and modulate the expression of thousands of genes. NIPBL loads cohesin onto chromosomes, and WAPL takes it off. Haploinsufficiency for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58b2d824c0513a624e332c8b105545b8
https://pubmed.ncbi.nlm.nih.gov/36449618
https://pubmed.ncbi.nlm.nih.gov/36449618
Decreasing Wapl dosage partially corrects transcriptome phenotypes in Nipbl-/+ embryonic mouse brain
Autor:
Connor M. Kean, Christopher J. Tracy, Apratim Mitra, Matthew T Van Winkle, Claudia M Gebert, Jacob Noeker, Anne L. Calof, Arthur D. Lander, Judith A. Kassis, Karl Pfeifer
Cohesin rings interact with DNA and modulate expression of thousands of genes. NIPBL loads cohesin onto chromosomes and WAPL takes it off. Heterozygous mutations in NIPBL lead to a developmental disorder called Cornelia de Lange syndrome. Nipbl heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7be961b450c7721577653b98e3e10c09
https://doi.org/10.1101/2022.05.31.493745
https://doi.org/10.1101/2022.05.31.493745
Autor:
Daniella P. Vansteenkiste, Christopher J. Tracy, Rebecca E.H. Whiting, Baye G. Williamson, Martin L. Katz, Jacqueline W. Pearce, Cheryl A. Jensen, Leilani J. Castaner, Jeffrey N. Bryan, Joan R. Coates, Lauren Elizabeth Gillespie
Publikováno v:
Experimental Eye Research. 152:77-87
The CLN2 form of neuronal ceroid lipofuscinosis is a neurodegenerative disease that results from mutations in the TPP1 gene. Affected children exhibit progressive declines in most neurological functions including vision. Functional declines are accom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ef7c59c8cc88658ef48811813fd4da
Autor:
Mark D. Kirk, Cheryl A. Jensen, Leilani J. Castaner, Jeffrey N. Bryan, Christopher J. Tracy, Douglas N. Sanders, Martin L. Katz
Publikováno v:
Retinal Degenerative Diseases ISBN: 9783319171203
A number of retinal degenerative diseases may be amenable to treatment with continuous intraocular delivery of therapeutic agents that cannot be delivered effectively to the retina via systemic or topical administration. Among these disorders are lys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2052894302821bfab0f4f35017b8e9
https://doi.org/10.1007/978-3-319-17121-0_76
https://doi.org/10.1007/978-3-319-17121-0_76
Publikováno v:
Physiologybehavior. 60(1)
Fischer 344 (F344) rats fail to prefer sodium chloride (NaCl) solution to water, and this behavior is dramatically altered by bilateral transection of the chorda tympani nerve (CTX). Tests of retention and generalization of a conditioned taste aversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205826a4b3f22d46dac848ee62941820
https://pubmed.ncbi.nlm.nih.gov/8804644
https://pubmed.ncbi.nlm.nih.gov/8804644