Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Christopher J. Thorpe"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundT cells form one of the key pillars of adaptive immunity. Using their surface bound T cell antigen receptors (TCRs), these cells screen millions of antigens presented by major histocompatibility complex (MHC) or MHC-like molecules. In other
Externí odkaz:
https://doaj.org/article/2331d3c5d2894b149ead1b291cba1917
Autor:
Christopher J. Thorpe, Todd R. Lewis, Matthew C. Fisher, Claudia J. Wierzbicki, Siddharth Kulkarni, David Pryce, Lewis Davies, Aparna Watve, Mairi E. Knight
Publikováno v:
Royal Society Open Science, Vol 5, Iss 6 (2018)
Batrachochytrium dendrobatidis (Bd) is a pathogen killing amphibians worldwide. Its impact across much of Asia is poorly characterized. This study systematically surveyed amphibians for Bd across rocky plateaus in the northern section of the Western
Externí odkaz:
https://doaj.org/article/8ee2c4cd47804bd4a6ad5796d31ca07e
Autor:
Lewis Davies, Todd R. Lewis, Mairi E. Knight, Siddharth Kulkarni, David Pryce, Christopher J. Thorpe, Aparna Watve, Claudia Wierzbicki, Matthew C. Fisher
Publikováno v:
Royal Society Open Science, Vol 5, Iss 6 (2018)
Royal Society Open Science
Royal Society Open Science
Batrachochytrium dendrobatidis(Bd) is a pathogen killing amphibians worldwide. Its impact across much of Asia is poorly characterized. This study systematically surveyed amphibians forBdacross rocky plateaus in the northern section of the Western Gha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bb9e749a7178552c1790d0e56dcd8e
http://hdl.handle.net/10044/1/61977
http://hdl.handle.net/10044/1/61977
Autor:
Siddharth Kulkarni, David Pryce, Lewis Davies, Todd R. Lewis, Mairi E. Knight, Christopher J. Thorpe, Nikhil Gaitonde, David T. Bilton, Aparna Watve
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194810 (2018)
PLoS ONE
PLoS ONE
The importance of patch quality for amphibians is frequently overlooked in distribution models. Here we demonstrate that it is highly important for the persistence of endemic and endangered amphibians found in the threatened and fragile ecosystems th
Autor:
Ning Zheng, Michael J. MacCoss, Christopher J. Thorpe, Randall T. Moon, Seth J. Goldenberg, Stephane Angers, Travis L. Biechele
Publikováno v:
Nature Cell Biology. 8:348-357
Dishevelled is a conserved protein that interprets signals received by Frizzled receptors. Using a tandem-affinity purification strategy and mass spectrometry we have identified proteins associated with Dishevelled, including a Cullin-3 ubiquitin lig
Autor:
Christopher J. Thorpe, Katrin Wuennenberg-Stapleton, Randall T. Moon, John Ngai, Gilbert Weidinger
Publikováno v:
Current Biology. 15:489-500
Summary Background: Wnt/β-catenin signaling regulates many processes during vertebrate development, including patterning of the mesoderm along the dorso-ventral axis and patterning of the neuroectoderm along the anterior-posterior axis during gastru
Publikováno v:
Physiological Genomics. 2:37-48
Lekven, Arne C., Kathryn Ann Helde, Christopher J. Thorpe, Rebecca Rooke, and Randall T. Moon. Reverse genetics in zebrafish. Physiol Genomics 2: 37–48, 2000.—The zebrafish has become a popular model system for the study of vertebrate development
Autor:
Hanne Quarsten, Gunnar Paulsen, Christopher J. Thorpe, Ludvig M. Sollid, Arne Holm, Bente H. Johansen, Søren Buus
Publikováno v:
International Immunology. 10:1229-1236
Susceptibility and resistance to type 1 diabetes are associated with MHC class II alleles that carry non-Asp and Asp at residue 57 of their beta chain respectively. The effect of Asp or non-Aspbeta57 may relate to a differential ability of distinct c
Autor:
Erik Thorsby, Tore Jensen, Ludvig M. Sollid, Frode Vartdal, Bente H. Johansen, Christopher J. Thorpe
Publikováno v:
Immunogenetics. 45:142-150
We compared the peptide binding specificity of three HLA-DQ molecules; HLA-DQ(alpha1(*)0501, beta1(*)0201), HLA-DQ(alpha1(*)0201, beta1(*)0202), and HLA-DQ(alpha1(*)0501, beta1(*)0301). The first of these molecules confers susceptibility to celiac di
Publikováno v:
European Journal of Immunology. 26:2895-2902
The P91A antigen was identified following mutation of P1 mastocytoma cells. The peptide epitope is encoded by a mutant form of the S3 subunit of the PA700 proteasome regulatory complex. P91A stimulates a strong CD8+ T cell response when expressed on