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pro vyhledávání: '"Christopher J. Tarr"'
Autor:
Anna L. Blobaum, Jane Wright, Jerri M. Rook, Christopher J. Tarr, Jeanette L. Bertron, Jonathan W. Dickerson, Elizabeth A. Ennis, Charles W. Locuson, Craig W. Lindsley, Randy D. Blakely
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(19)
This Letter describes the further lead optimization of the CHT inhibitor probe, ML352 (VU0476201), and the development of VU6001221, an improved in vivo tool. A multi-dimensional optimization effort encountered steep SAR, and ultimately, subtle tunin
Publikováno v:
Microsurgery. 20:105-108
Although the tongue is not a vital organ in sustaining life, it may be a vital organ in sustaining the will to live in many people. As carcinoma of the tongue represents the majority of the 30,000 oral cavity cancers diagnosed per year in the United