Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Christopher J. Sinz"'
Autor:
Joseph Carpenter, Robert R. Knowles, Simon B. Blakey, Ian Mangion, Akio Kayano, Christopher J. Sinz, David W. C. MacMillan
Publikováno v:
Chem. Sci.. 2:308-311
A total synthesis of the marine natural product diazonamide A (1) has been accomplished. This work features a highly stereoselective synthesis of the C(10) quaternary center and the central furanoindoline core enabled by an iminium-catalyzed alkylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e5fbf8dad75fdee6522aca9f7edd09
https://doi.org/10.1039/c0sc00577k
https://doi.org/10.1039/c0sc00577k
Publikováno v:
Proceedings of the National Academy of Sciences. 101:5482-5487
Pyrroloindoline and bispyrroloindoline are a subclass of alkaloid structural motifs that commonly exhibit biological activity. An enantioselective organocatalytic approach to the synthesis of pyrroloindoline architecture is described. The addition–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1983e35ea72f785db5bec4592fd5f566
https://doi.org/10.1073/pnas.0308177101
https://doi.org/10.1073/pnas.0308177101
Publikováno v:
Tetrahedron. 58:6561-6576
Herein we provide full details of studies which culminated in the first total synthesis of the polyene macrolide dermostatin A, confirming our earlier stereochemical assignment. A highly convergent synthesis was developed, featuring the cyanohydrin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb8be58147cac91273b0d5b665dde99b
https://doi.org/10.1016/s0040-4020(02)00666-x
https://doi.org/10.1016/s0040-4020(02)00666-x
Publikováno v:
Angewandte Chemie International Edition. 40:3224-3227
An oxo-hexaene macrolide antibiotic, dermostatin A has been synthesized. Key features of the synthesis include the application of cyanohydrin acetonide couplings for the synthesis of the polyol portion, and the convergent introduction of the polyene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd549c772624558340a330ee5582d57
https://doi.org/10.1002/1521-3773(20010903)40:17<3224::aid-anie3224>3.0.co
https://doi.org/10.1002/1521-3773(20010903)40:17<3224::aid-anie3224>3.0.co
Publikováno v:
Tetrahedron Letters. 39:6811-6814
Lewis acids promote the coupling of 4-acetoxy-1,3-dioxanes 1 with crotyl-metal species to generate propionate motifs such as 2. The reactions show a marked dependence on Lewis acid, the crotyl metal species, and the presence and stereochemical dispos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::234ed3e7afeae8e7b74f473476c09e36
https://doi.org/10.1016/s0040-4039(98)01464-6
https://doi.org/10.1016/s0040-4039(98)01464-6
Publikováno v:
ChemInform. 29
Lewis acids promote the coupling of 4-acetoxy-1,3-dioxanes 1 with crotyl-metal species to generate propionate motifs such as 2. The reactions show a marked dependence on Lewis acid, the crotyl metal species, and the presence and stereochemical dispos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448a6b997668e474fc676c8d96d7cd97
https://doi.org/10.1002/chin.199849194
https://doi.org/10.1002/chin.199849194
Publikováno v:
ChemInform. 32
An oxo-hexaene macrolide antibiotic, dermostatin A has been synthesized. Key features of the synthesis include the application of cyanohydrin acetonide couplings for the synthesis of the polyol portion, and the convergent introduction of the polyene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52dc83b73c4c0873b035f5fd22f9c722
https://doi.org/10.1002/chin.200150215
https://doi.org/10.1002/chin.200150215
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::922a8dd1a697cd190ba690342f1102dd
https://doi.org/10.1002/chin.200224268
https://doi.org/10.1002/chin.200224268
Publikováno v:
ChemInform. 33
Herein we provide full details of studies which culminated in the first total synthesis of the polyene macrolide dermostatin A, confirming our earlier stereochemical assignment. A highly convergent synthesis was developed, featuring the cyanohydrin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ad6bc4afcc5eef577bbc60368b152b4
https://doi.org/10.1002/chin.200250204
https://doi.org/10.1002/chin.200250204
The first direct enantioselective catalytic alpha-oxidation of carbonyls has been accomplished. The use of enamine catalysis has provided a new organocatalytic strategy for the enantioselective oxyamination of aldehydes, to generate alpha-oxyaldehyde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7027d779e8aeff36444b9e635e9203
https://resolver.caltech.edu/CaltechAUTHORS:20170419-130607059
https://resolver.caltech.edu/CaltechAUTHORS:20170419-130607059
