Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Christopher J. Pierini"'
Autor:
Jennifer R. Litowski, Xiaolin Cao, Christine C. Siska, R. Matthew Fesinmeyer, Stephen R. Brych, Gerd R. Kleemann, Christopher J. Pierini, Zai-Qing Wen
Publikováno v:
Journal of pharmaceutical sciences. 104(2)
We report, for the first time, the identification of fatty acid particles in formulations containing the surfactant polysorbate 20. These fatty acid particles were observed in multiple mAb formulations during their expected shelf life under recommend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99b25426a211dbb66e15b5805a7a015
https://pubmed.ncbi.nlm.nih.gov/25175016
https://pubmed.ncbi.nlm.nih.gov/25175016
Autor:
Ramil F. Latypov, Christopher J. Pierini, Christine C. Siska, Jennifer R. Litowski, Hollis Lau, R. Matthew Fesinmeyer
Publikováno v:
Journal of pharmaceutical sciences. 104(2)
Polysorbate 20 (PS20) is a nonionic surfactant frequently used to stabilize protein biopharmaceuticals. During the development of mAb formulations containing PS20, small clouds of particles were observed in solutions stored in vials. The degree of pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00f1b48eb649e28c44791c5dc05cc0a
https://pubmed.ncbi.nlm.nih.gov/25196966
https://pubmed.ncbi.nlm.nih.gov/25196966