Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Christopher J. Nicol"'
Publikováno v:
PPAR Research, Vol 2012 (2012)
Externí odkaz:
https://doaj.org/article/85dbc1c6374c4195a2a502c4ac4c7a2a
Autor:
Robert J Evans, Katherine Pline, Catherine A Loynes, Sarah Needs, Maceler Aldrovandi, Jens Tiefenbach, Ewa Bielska, Rachel E Rubino, Christopher J Nicol, Robin C May, Henry M Krause, Valerie B O'Donnell, Stephen A Renshaw, Simon A Johnston
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1009058 (2020)
[This corrects the article DOI: 10.1371/journal.ppat.1007597.].
Externí odkaz:
https://doaj.org/article/22138a71e80440478697917cedc11f4d
Autor:
Robert J Evans, Katherine Pline, Catherine A Loynes, Sarah Needs, Maceler Aldrovandi, Jens Tiefenbach, Ewa Bielska, Rachel E Rubino, Christopher J Nicol, Robin C May, Henry M Krause, Valerie B O'Donnell, Stephen A Renshaw, Simon A Johnston
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007597 (2019)
Cryptococcus neoformans is one of the leading causes of invasive fungal infection in humans worldwide. C. neoformans uses macrophages as a proliferative niche to increase infective burden and avoid immune surveillance. However, the specific mechanism
Externí odkaz:
https://doaj.org/article/1a08a7430145486bae0ce55dcf6c2043
Autor:
Shiang-Jiuun Chen, Ming-Chang Chiang, Chuan Wan, Rong-Nan Huang, Chien-Hung Lin, Christopher J. Nicol
Publikováno v:
NeuroToxicology. 88:25-35
Ambient air pollution is a global public health issue. Recent evidence suggests that exposure to fine aerosolized particulate matter (PM) as small as ≤2.5 microns (PM2.5) is neurotoxic to brain structures. Many studies also suggest exposure to PM2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::213065863035569488d81645efedcc8d
https://doi.org/10.1016/j.neuro.2021.10.009
https://doi.org/10.1016/j.neuro.2021.10.009
Autor:
Elizabeth Lightbody, Bruce E. Elliott, Stephen L. Archer, Edward A. Sykes, Patricia D.A. Lima, Kuang-Hueih Chen, Ashley Martin, Charles C.T. Hindmarch, Yolanda Madarnas, Sandip SenGupta, Leah R. G. Parlow, Jeffrey Mewburn, Christopher J. Nicol, Chandrakant Tayade, Danchen Wu, Victoria Hoskin, Asish Dasgupta
Publikováno v:
The FASEB Journal. 34:5106-5127
Excessive proliferation and apoptosis-resistance are hallmarks of cancer. Increased dynamin-related protein 1 (Drp1)-mediated mitochondrial fission is one of the mediators of this phenotype. Mitochondrial fission that accompanies the nuclear division
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148d112ecd0d5709b0d7e64a27be123b
https://doi.org/10.1096/fj.201903117r
https://doi.org/10.1096/fj.201903117r
Publikováno v:
Brain research bulletin. 178
Alzheimer's disease (AD) is the major cause of neurodegeneration worldwide and is characterized by the accumulation of amyloid beta (Aβ) in the brain, which is associated with neuronal loss and cognitive impairment. Liver X receptor (LXR), a critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a352aaea876f3179df3e7d0c77509c
https://pubmed.ncbi.nlm.nih.gov/34801648
https://pubmed.ncbi.nlm.nih.gov/34801648
Autor:
Lesley Mcnamara, Christopher J. Nicol, Emanuel Zycband, C. H. Chang, Haiying Liu, Elizabeth Lightbody, Neelam Sharma, Frank J. Gonzalez, Rachel E. Rubino, Jia Yue Shi, Taro E. Akiyama, Joel P. Berger, Graham Skelhorne-Gross, John Woods
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 368:514-523
Thiazolidinediones (TZDs) are peroxisome proliferator-activated receptor γ (PPARγ) agonists that represent an effective class of insulin-sensitizing agents; however, clinical use is associated with weight gain and peripheral edema. To elucidate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2adc48a9d8a14f64019db9af30380e58
https://doi.org/10.1124/jpet.118.250985
https://doi.org/10.1124/jpet.118.250985
Autor:
Qing Ling Duan, Danai G. Topouza, Sean Nesdoly, Anastasiya Tarnouskaya, Jihoon Choi, Christopher J. Nicol
BackgroundHigh-grade serous ovarian cancer (HGSOC) is a highly lethal gynecologic cancer, in part due to resistance to platinum-based chemotherapy reported among 20% of patients. This study aims to characterize the biological mechanisms underlying ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f483c42e636a6555a7c04532b9f68f
https://doi.org/10.21203/rs.3.rs-452935/v1
https://doi.org/10.21203/rs.3.rs-452935/v1
Autor:
Christopher J. Nicol, Anastasiya Tarnouskaya, Sean Nesdoly, Qing Ling Duan, Danai G. Topouza, Jihoon Choi
BackgroundHigh-grade serous ovarian cancer (HGSOC) is a highly lethal gynecologic cancer, in part due to resistance to platinum-based chemotherapy reported among 20% of patients. This study aims to elucidate the biological mechanisms underlying chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aff182a28fa0dade069772bc0f8ac3e
https://doi.org/10.1101/2020.09.09.289868
https://doi.org/10.1101/2020.09.09.289868
Autor:
Christopher J. Nicol, Parvin Mousavi, Mark Asselin, Laura Connolly, Rachel E. Rubino, Alireza Sedghi, Tamas Ungi, Amoon Jamzad, Gabor Fichtinger, Scott S.-H. Yam, John F. Rudan, Martin Kaufmann
Publikováno v:
Medical Imaging: Image-Guided Procedures
PURPOSE: The iKnife is a new surgical tool designed to aid in tumor resection procedures by providing enriched chemical feedback about the tumor resection cavity from electrosurgical vapors. We build and compare machine learning classifiers that are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::128bb6065be8b4a0fcb3537ba35e53ce
https://doi.org/10.1117/12.2549343
https://doi.org/10.1117/12.2549343