Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christopher J. Moressi"'
Autor:
Craig J. Benham, Christopher J. Moressi, Todd E. Scheetz, Prashanth Ak, Thomas L. Casavant, Diane Thi Tran, Yubin Kang, Paul B. McCray, Litao Xie, Beverly L. Davidson
Publikováno v:
Journal of Virology. 80:8820-8823
We mapped 226 unique integration sites in human hepatoma cells following gene transfer with a feline immunodeficiency virus (FIV)-based lentivirus vector. FIV integrated across the entire length of the transcriptional units. Microarray data indicated
Publikováno v:
Molecular Therapy. 13
We are investigating the nonprimate FIV lentiviral vector for gene transfer applications. Although this vector can integrate in transduced cells, little is known about the fate of FIV vector in host cells after infection. Transgenic DNA can persist a
Autor:
Christopher J. Moressi, Litao Xie, Diane Thi Tran, Todd E. Scheetz, Beverly L. Davidson, Paul B. McCray, Yubin Kang, Thomas L. Casavant
Publikováno v:
Molecular Therapy. 9:S2
Retroviral vector-mediated gene transfer holds promise in the treatment of a variety of genetic diseases. A distinguishing feature of retroviral vectors is their ability to integrate into the host genome, resulting in sustained transgene expression.