Chemoenzymatic Synthesis of (−)-Ribisins A and B from Dibenzo[b,d]furan

Autor: Derek R. Boyd, Christopher J. McGivern, Christopher C. R. Allen, Patrick Hoering, Narain D. Sharma, Paul J. Stevenson

Publikováno v: Boyd, D R, Sharma, N D, McGivern, C J, Stevenson, P J, Hoering, P & Allen, C C R 2019, ' Chemoenzymatic Synthesis of (-)-Ribisins A and B from Dibenzo[b,d]furan ', Journal of Organic Chemistry, vol. 84, pp. 15165-15172 . https://doi.org/10.1021/acs.joc.9b02171

cis-Dihydrodiols, derived from monocyclic aromatic compounds, are valuable chiral pool intermediates for the synthesis of cyclic natural products. A drawback of this approach, to the synthesis of polycyclic secondary metabolites, is that additional r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116e5cf34ba923309944116d98b55157
https://doi.org/10.1021/acs.joc.9b02171

cis‐Dihydroxylation of Tricyclic Arenes and Heteroarenes Catalyzed by Toluene Dioxygenase: A Molecular Docking Study and Experimental Validation

Autor: Christopher J. McGivern, Christopher C. R. Allen, Ian N. Brannigan, Derek R. Boyd, Narain D. Sharma, Colin McRoberts, Peter Nockemann, Patrick Hoering, Paul J. Stevenson

Publikováno v: Boyd, D, Sharma, N D, Brannigan, I, McGivern, C, Nockemann, P, Stevenson, P, McRoberts, C, Hoering, P & Allen, C C R 2019, ' cis-Dihydroxylation of Tricyclic Arenes and Heteroarenes Catalyzed by Toluene Dioxygenase: A Molecular Docking Study and Experimental Validation ', Advanced Synthesis & Catalysis . https://doi.org/10.1002/adsc.201900147

Molecular docking studies of toluene dioxygenase (TDO) led to the prediction that angular and lateral cis‐dihydroxylation of tricyclic arene and heteroarene substrates could occur. Biotransformations of biphenylene, dibenzofuran, carbazole and dibe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb12ef426b292992c8055c73cf641007
https://pure.qub.ac.uk/en/publications/cisdihydroxylation-of-tricyclic-arenes-and-heteroarenes-catalyzed-by-toluene-dioxygenase-a-molecular-docking-study-and-experimental-validation(50853b4a-7862-402a-80bc-d5045176e60a).html