Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christopher J. Leonard"'
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007526 (2018)
Understanding the role of chromosomal inversions in speciation is a fundamental problem in evolutionary genetics. Here, we perform a comprehensive reconstruction of the evolutionary histories of the chromosomal inversions in Drosophila persimilis and
Externí odkaz:
https://doaj.org/article/c6d5ce2d56d04f4381532b6aa3e68d45
Autor:
Christopher J. Leonard, Randee E. Young, Stephen W. Schaeffer, Spencer A Koury, Zachary L. Fuller, Jonathan Westlake, Nitin Phadnis, Kobe Ikegami, Stephen Richards
Publikováno v:
Genetics. 216:205-226
Sex-Ratio (SR) chromosomes are selfish X-chromosomes that distort Mendelian segregation and are commonly associated with inversions. These chromosomal rearrangements suppress recombination with Standard (ST) X-chromosomes and are hypothesized to main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::444ca131eb43851040d7ed7182b8a17b
https://doi.org/10.1534/genetics.120.303460
https://doi.org/10.1534/genetics.120.303460
Autor:
Jacob C Cooper, Eric F. Joyce, Nitin Phadnis, Son C. Nguyen, Christopher J. Leonard, Thomas D King
Publikováno v:
Molecular Biology and Evolution
Condensins play a crucial role in the organization of genetic material by compacting and disentangling chromosomes. Based on studies in a few model organisms, the condensins I and II complexes are considered to have distinct functions, with the conde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146c01fe8780df5f754817a64839a4fe
https://doi.org/10.1093/molbev/msz140
https://doi.org/10.1093/molbev/msz140
Autor:
Zachary L, Fuller, Spencer A, Koury, Christopher J, Leonard, Randee E, Young, Kobe, Ikegami, Jonathan, Westlake, Stephen, Richards, Stephen W, Schaeffer, Nitin, Phadnis
Publikováno v:
Genetics
The Drosophila pseudoobscura Sex-Ratio (SR) chromosome was one of the first-discovered segregation distorter chromosomes. Despite being a historically significant and well-studied segregation distortion system, the mechanisms allowing for the long-te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::876bf09e6077de7564dcdf3999d85a1f
https://pubmed.ncbi.nlm.nih.gov/32732371
https://pubmed.ncbi.nlm.nih.gov/32732371
Autor:
Clayton M. Carey, Jacob C Cooper, Nitin Phadnis, Christopher J. Leonard, Aaron R. Quinlan, Nels C. Elde, Brent S. Pedersen
Recurrent positive selection at the codon level is often a sign that a gene is engaged in a molecular arms race – a conflict between the genome of its host and the genome of another species over mutually exclusive access to a resource that has a di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a37cf3fdcc96d3d3e1a72c1657432f4
https://doi.org/10.1101/685321
https://doi.org/10.1101/685321
Autor:
Stephen Richards, Spencer A Koury, Nitin Phadnis, Christopher J. Leonard, Stephen W. Schaeffer, Westlake J, Randee E. Young, Zachary L. Fuller, Ikegami K
Segregation distorters violate Mendelian Inheritance by over-representing themselves in the progeny of carrier individuals and are commonly associated with chromosomal inversions. When distorting alleles are found on sex chromosomes, the progeny of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38d8b09c66def729593155cf58c0dd1
Autor:
Nitin Phadnis, Christopher J. Leonard, Zachary L. Fuller, Stephen W. Schaeffer, Randee E. Young
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 7, p e1007526 (2018)
PLoS Genetics, Vol 14, Iss 7, p e1007526 (2018)
Understanding the role of chromosomal inversions in speciation is a fundamental problem in evolutionary genetics. Here, we perform a comprehensive reconstruction of the evolutionary histories of the chromosomal inversions in Drosophila persimilis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc9b97298a2edf4a086b3669c7de3e6
https://doi.org/10.1371/journal.pgen.1007526
https://doi.org/10.1371/journal.pgen.1007526
Publikováno v:
Genome Research. 8:1038-1047
The central role of serine/threonine and tyrosine protein kinases in signal transduction and cellular regulation in eukaryotes is well established and widely documented. Considerably less is known about the prevalence and role of these protein kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff732408c2fd3c355df9709809da230
https://doi.org/10.1101/gr.8.10.1038
https://doi.org/10.1101/gr.8.10.1038
Publikováno v:
Cancer and Metastasis Reviews. 14:3-15
Cellular proliferation depends on the rates of both cell division and cell death. Tumors frequently have decreased cell death as a primary mode of increased cell proliferation. Genetic changes resulting in loss of programmed cell death (apoptosis) ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dcc793a4d2b2e82e20d3c6c862f68f
https://doi.org/10.1007/bf00690207
https://doi.org/10.1007/bf00690207
Publikováno v:
Virology. 200:566-573
Using the vaccinia virus/T7-RNA polymerase transient protein expression system, the AAV Rep78 protein was expressed in mammalian cells. Rep78 protein was found localized primarily to the nucleus of cells. Maximal steady-state protein levels were reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74e628b265dd10bccfec257baedad7b
https://doi.org/10.1006/viro.1994.1219
https://doi.org/10.1006/viro.1994.1219