Renal and Blood Pressure Response to a High-Salt Diet in Mice With Reduced Global Expression of the Glucocorticoid Receptor

Autor: Jessica R. Ivy, Louise C. Evans, Rebecca Moorhouse, Rachel V. Richardson, Emad A. S. Al-Dujaili, Peter W. Flatman, Christopher J. Kenyon, Karen E. Chapman, Matthew A. Bailey

Publikováno v: Frontiers in Physiology, Vol 9 (2018)

Salt-sensitive hypertension is common in glucocorticoid excess. Glucocorticoid resistance also presents with hypercortisolemia and hypertension but the relationship between salt intake and blood pressure (BP) is not well defined. GRβgeo/+ mice have

Externí odkaz: https://doaj.org/article/2c0e2c5eb9cb4c6c85491957ffa6e03f

Glucocorticoid involvement in reproductive biology

Autor: Linda J. Mullins, Steven D. Morley, Christopher J. Kenyon, John J. Mullins

Oestrogen and progesterone play essential roles in the release of mature oocytes, the priming and cycling of the uterine lining, and the maintenance of mammalian pregnancy. Progesterone is synthesizedde novoat the embryo implantation site in the mous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebf76c859a074403637bbdaadf3c64bc
https://doi.org/10.1101/2022.11.03.515013

Neisseria Mucosa Does Not Inhibit the Growth of Neisseria gonorrhoeae

Autor: Sheeba S Manoharan-Basil, Delphine Martiny, Jolein Laumen, Christopher J. Kenyon, Saïd Abdellati, Christophe Van Dijck, Irith De Baetselier, Natalia Gonzalez, Tessa De Block

Publikováno v: Sci; Volume 4; Issue 1; Pages: 8

Antibiotic-sparing treatments are required to prevent the further emergence of antimicrobial resistance in Neisseria gonorrhoeae. Commensal Neisseria species have previously been found to inhibit the growth of pathogenic Neisseria species. For exampl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d38bd174f757ee030b7f778499f52d6
https://doi.org/10.20944/preprints202111.0348.v1

Recurrent Sexually Transmitted Infections Among a Cohort of Men Who Have Sex With Men Using Preexposure Prophylaxis in Belgium Are Highly Associated With Sexualized Drug Use

Autor: Jozefien Buyze, Tania Crucitti, Bea Vuylsteke, Thijs Reyniers, Christiana Nöstlinger, Kristien Wouters, Tom Platteau, Irith De Baetselier, Marie Laga, Vicky Cuylaerts, Christopher J. Kenyon

Publikováno v: Sexually Transmitted Diseases, 48(10), 726-732. Lippincott Williams and Wilkins Ltd.
Platteau, T M I, De Baetselier, I, Reyniers, T, Wouters, K, Nöstlinger, C, Cuylaerts, V, Buyze, J, Laga, M, Kenyon, C R, Crucitti, T & Vuylsteke, B 2021, ' Recurrent sexually transmitted infections among a cohort of men who have sex with men using pre-exposure prophylaxis in Belgium are highly associated with sexualized drug use ', Sexually Transmitted Diseases, vol. 48, no. 10, pp. 726-732 . https://doi.org/10.1097/olq.0000000000001424

BACKGROUND Men who have sex with men (MSM) experiencing recurrent sexually transmitted infections (STIs) may play a crucial role in the STI epidemic. However, there is limited understanding of what kind of behavior leads to recurrent STIs. METHODS A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5afb8a0ae043c6c2f6f8f677a923be2
https://pubmed.ncbi.nlm.nih.gov/34110745

Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness

Autor: Sergio Rodriguez-Cuenca, Gary A. Churchill, Antonio Vidal-Puig, Maximilian Zeyda, Nicholas M. Morton, Annalisa Gastaldello, Jasmina Beltram, Scott P. Webster, Gregor Gorjanc, Aila Saari, Thomas M. Stulnig, Simon Horvat, Vilmundur Gudnason, Roderick N. Carter, Matthew T G Gibbins, José Manuel Fernández-Real, Jonathan R. Seckl, Steven C. Munger, Clare McFadden, Gregorio Naredo, Martin E. Barrios-Llerena, Donald R. Dunbar, Christopher J Kenyon, Zhao V. Wang, Alexander F. Howie, Lynne Ramage, José María Moreno-Navarrete, Karen L. Svenson, Brian R. Walker, Valur Emilsson, Petra Sipilä, Zoi Michailidou, Rhona Aird

Publikováno v: Morton, N M, Beltram, J, Carter, R N, Michailidou, Z, Gorjanc, G, McFadden, C, Barrios-Llerena, M E, Rodriguez-Cuenca, S, Gibbins, M T G, Aird, R E, Moreno-Navarrete, J M, Munger, S C, Svenson, K L, Gastaldello, A, Ramage, L, Naredo, G, Zeyda, M, Wang, Z V, Howie, A F, Saari, A, Sipilä, P, Stulnig, T M, Gudnason, V, Kenyon, C J, Seckl, J R, Walker, B R, Webster, S P, Dunbar, D R, Churchill, G A, Vidal-Puig, A, Fernandez-Real, J M, Emilsson, V & Horvat, S 2016, ' Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness ', Nature Medicine, vol. 22, no. 7, pp. 771-779 . https://doi.org/10.1038/nm.4115
Nature medicine
© Nature Medicine, 2016, vol. 22, p. 771-779
Articles publicats (D-CM)
DUGiDocs – Universitat de Girona
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The discovery of genetic mechanisms for resistance to obesity and diabetes may illuminate new therapeutic strategies for the treatment of this global health challenge. We used the polygenic 'lean' mouse model, which has been selected for low adiposit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d97883a5e7915270071cddd2f0f72e6
https://hdl.handle.net/2072/372198