Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christopher J. Kay"'
Autor:
Christopher J. Kay
Publikováno v:
FEBS Letters. 403:230-235
β-Amyloid peptides (Aβ) form the core of Alzheimer's disease (AD) senile plaques, and are implicated in AD neurotoxicity. Aβ and some derivatives generate free radicals upon fibrilogenesis. A mechanism for free radical generation is proposed, base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3a5be08f39a9f536883014ce00103c
https://doi.org/10.1016/s0014-5793(97)00076-8
https://doi.org/10.1016/s0014-5793(97)00076-8
Publikováno v:
Biochemistry. 35:14109-14117
5-Aminolevulinate synthase catalyzes the first step of the heme biosynthetic pathway in animals, fungi, and some bacteria. The enzyme belongs to a large family of enzymes that use pyridoxal 5'-phosphate as an essential cofactor. We previously analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c63e251930bd92c3b018e68d1e4eb8f
https://doi.org/10.1021/bi961296h
https://doi.org/10.1021/bi961296h
Autor:
Christopher J. Kay, Eric W. Lippay
Publikováno v:
Biochemistry. 31:11376-11382
Kinetic and thermodynamic properties of yeast flavocytochrome b2 (EC 1.1.2.3) are modified by the product pyruvate, which binds to the flavosemiquinone (FSQ) form of the prosthetic flavin and decreases the thermodynamic driving force for electron tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1a5ace38feaf0d387fa206ec4ea299
https://doi.org/10.1021/bi00161a015
https://doi.org/10.1021/bi00161a015
Publikováno v:
Biochemistry. 30:11445-11450
Assimilatory nitrate reductase (NR) from Chlorella is homotetrameric, each subunit containing FAD, heme, and Mo-pterin in a 1:1:1 stoichiometry. Measurements of NR activity and steady-state reduction of the heme component under conditions of NADH lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef83bbf7bf1779337a7ecf3e92c0a70e
https://doi.org/10.1021/bi00112a011
https://doi.org/10.1021/bi00112a011
Autor:
Christopher J. Kay, Andrew C. Cannons, Charles R. Hipkin, Larry P. Solomonson, David A. Kau, Michael J. Barber
Publikováno v:
Biochemical Journal. 272:545-548
Visible spectra of oxidized and reduced Candida nitratophila assimilatory NAD(P)H:nitrate reductase yielded absorbance maxima of 413 nm and 423 nm, and 525 nm and 555 nm respectively, characteristic of a b5-type cytochrome. E.p.r. spectra of the part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b82f9cda3f0e3d0d596ed3034150dc3
https://doi.org/10.1042/bj2720545
https://doi.org/10.1042/bj2720545
Autor:
Christopher J. Kay, Michael J. Barber
Publikováno v:
Analytical Biochemistry. 184:11-15
A room temperature electron paramagnetic resonance potentiometric cell has been developed for the measurement of oxidation-reduction midpoint potentials of enzymes containing paramagnetic centers. Based upon an aqueous flat cell designed for use with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adf5316db84d79a362b36b0df93ac5d
https://doi.org/10.1016/0003-2697(90)90003-r
https://doi.org/10.1016/0003-2697(90)90003-r
Autor:
Christopher J. Kay, Michael J. Barber
Publikováno v:
Archives of biochemistry and biophysics. 326(2)
Assimilatory NADH:nitrate reductase catalyzes the transfer of reducing equivalents from NADH to molecular oxygen. Initial rate studies performed under conditions of optimum pH (8.0) and constant ionic strength (μ = 0.2) revealed that the maximal rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5db3400cef15b6a350afaf65d555b8
https://pubmed.ncbi.nlm.nih.gov/8611027
https://pubmed.ncbi.nlm.nih.gov/8611027
Publikováno v:
Biochemistry. 29(48)
Potentiometric titrations of assimilatory nitrate reductase from Chlorella vulgaris were performed within the pH range 6.0-9.0. Mo(V) was measured by room temperature EPR spectroscopy while the reduction state of FAD was monitored by CD spectroscopy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68103027fdad7deecbd1f232001f3bf9
https://pubmed.ncbi.nlm.nih.gov/2176886
https://pubmed.ncbi.nlm.nih.gov/2176886
Publikováno v:
Plant Physiology. 90:70-74
Initial rate studies of spinach (Spinacia oleracea L.) nitrate reductase showed that NADH:nitrate reductase activity was ionic strength dependent with elevated ionic concentration resulting in inhibition. In contrast, NADH:ferricyanide reductase was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84fbffd1f7396ba56dec2c3f63c8d51e
https://doi.org/10.1104/pp.90.1.70
https://doi.org/10.1104/pp.90.1.70
Publikováno v:
Biochemistry. 27:6142-6149
Oxidation-reduction midpoint potentials for flavin, heme, and molybdenum-pterin prosthetic groups of assimilatory nitrate reductase (NR) from Chlorella vulgaris were measured at room temperature by using CD and EPR potentiometry. The CD changes accom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d64c1f492226be6b2f719a12a41ecd19
https://doi.org/10.1021/bi00416a047
https://doi.org/10.1021/bi00416a047