Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Christopher J. Hunter"'
Autor:
Lauren Schiff, Bianca Migliori, Ye Chen, Deidre Carter, Caitlyn Bonilla, Jenna Hall, Minjie Fan, Edmund Tam, Sara Ahadi, Brodie Fischbacher, Anton Geraschenko, Christopher J. Hunter, Subhashini Venugopalan, Sean DesMarteau, Arunachalam Narayanaswamy, Selwyn Jacob, Zan Armstrong, Peter Ferrarotto, Brian Williams, Geoff Buckley-Herd, Jon Hazard, Jordan Goldberg, Marc Coram, Reid Otto, Edward A. Baltz, Laura Andres-Martin, Orion Pritchard, Alyssa Duren-Lubanski, Ameya Daigavane, Kathryn Reggio, NYSCF Global Stem Cell Array® Team, Phillip C. Nelson, Michael Frumkin, Susan L. Solomon, Lauren Bauer, Raeka S. Aiyar, Elizabeth Schwarzbach, Scott A. Noggle, Frederick J. Monsma, Daniel Paull, Marc Berndl, Samuel J. Yang, Bjarki Johannesson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
By coupling robotic cell culture systems with artificial intelligence–powered image analysis, Schiff et al. identify previously unseen characteristics of Parkinson’s disease in patient skin cells that distinguish them from healthy controls.
Externí odkaz:
https://doaj.org/article/9d8265097577462f83aa83bf77ad2240
Autor:
Lauren, Schiff, Bianca, Migliori, Ye, Chen, Deidre, Carter, Caitlyn, Bonilla, Jenna, Hall, Minjie, Fan, Edmund, Tam, Sara, Ahadi, Brodie, Fischbacher, Anton, Geraschenko, Christopher J, Hunter, Subhashini, Venugopalan, Sean, DesMarteau, Arunachalam, Narayanaswamy, Selwyn, Jacob, Zan, Armstrong, Peter, Ferrarotto, Brian, Williams, Geoff, Buckley-Herd, Jon, Hazard, Jordan, Goldberg, Marc, Coram, Reid, Otto, Edward A, Baltz, Laura, Andres-Martin, Orion, Pritchard, Alyssa, Duren-Lubanski, Ameya, Daigavane, Kathryn, Reggio, Phillip C, Nelson, Michael, Frumkin, Susan L, Solomon, Lauren, Bauer, Raeka S, Aiyar, Elizabeth, Schwarzbach, Scott A, Noggle, Frederick J, Monsma, Daniel, Paull, Marc, Berndl, Samuel J, Yang, Bjarki, Johannesson
Publikováno v:
Nature communications. 13(1)
Drug discovery for diseases such as Parkinson’s disease are impeded by the lack of screenable cellular phenotypes. We present an unbiased phenotypic profiling platform that combines automated cell culture, high-content imaging, Cell Painting, and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf40f717a4188a14b75644189e5a474
https://pubmed.ncbi.nlm.nih.gov/35338121
https://pubmed.ncbi.nlm.nih.gov/35338121
Autor:
Heather N. Bader, Daniel Paull, Carina Seah, Tom Rusielewicz, Migle Staniskyte, Rachel Yehuda, Mitali Chattopadhyay, Michael S. Breen, Barry McCarthy, Kristen J. Brennand, Changxin Xu, Linda M. Bierer, Nyscf Global Array Team, Janine D. Flory, Christopher J. Hunter, Frank Desarnaud, Iouri Makotkine, Scott Noggle
Post-traumatic stress disorder (PTSD) results from severe trauma exposure, but the extent to which genetic and epigenetic risk factors impact individual clinical outcomes is unknown. We assessed the impact of genomic differences following glucocortic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::018694ebc67d5899191d6b2e4c6561e8
https://doi.org/10.1101/2021.03.01.433391
https://doi.org/10.1101/2021.03.01.433391
Autor:
Minjie Fan, Samuel Yang, Orion Pritchard, Sean DesMarteau, Zan Armstrong, Selwyn Jacob, Marc Coram, Peter Ferrarotto, Edward A. Baltz, Lauren Schiff, Edmund Tam, Alyssa Duren-Lubanski, Ameya Daigavane, Geoff Buckley-Herd, Brian Williams, Elizabeth Schwarzbach, Raeka S. Aiyar, Jordan Goldberg, Jenna Hall, Daniel Paull, Deidre Carter, Marc Berndl, Scott Noggle, Reid Otto, Jon Hazard, Frederick J. Monsma, Lauren Bauer, Caitlyn Bonilla, Brodie Fischbacher, Bianca Migliori, Ye Chen, Sara Ahadi, Bjarki Johannesson, Subhashini Venugopalan, Christopher J. Hunter, Arunachalam Narayanaswamy, Anton Geraschenko, Kathryn Reggio, Laura Andres-Martin
Drug discovery for diseases such as Parkinson’s disease are impeded by the lack of screenable cellular phenotypes. We present an unbiased phenotypic profiling platform that combines automated cell culture, high-content imaging, Cell Painting, and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0736c9ee7dda2c99486a56f923ee84dc
https://doi.org/10.1101/2020.11.13.380576
https://doi.org/10.1101/2020.11.13.380576
Autor:
Xu C, Staniskyte M, Tom Rusielewicz, Daniel Paull, Iouri Makotkine, Michael S. Breen, Linda M. Bierer, Scott Noggle, Kristen J. Brennand, Frank Desarnaud, Rachel Yehuda, Mitali Chattopadhyay, Christopher J. Hunter, Janine D. Flory, Heather N. Bader, Carina Seah, McCarthy B
Publikováno v:
European Neuropsychopharmacology. 51:e30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::895e0b75562a8cb2ecec6193f0b82cd3
https://doi.org/10.1016/j.euroneuro.2021.07.072
https://doi.org/10.1016/j.euroneuro.2021.07.072
Autor:
Rachel Toth, Christopher J. Hunter, J. Simon C. Arthur, Lucia Privitera, Judit Remenyi, Bruno G. Frenguelli, Kirsty J. Martin, Sônia A. L. Corrêa, Kathleen M. S. E. Reyskens
Publikováno v:
FEBS Open Bio
The immediate early gene activity-regulated cytoskeletal protein (Arc)/Arg3.1 and the neurotrophin brain-derived neurotrophic factor (BDNF) play important roles in synaptic plasticity and learning and memory in the mammalian brain. However, the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a19991976f36bd14ef69a2a43c9d61
https://doi.org/10.1002/2211-5463.12232
https://doi.org/10.1002/2211-5463.12232
Publikováno v:
Journal of Biomechanics. 46:116-121
The relationships between mechanical inputs and resulting biological tissue structure, composition, and metabolism are critical to detailing the nuances of tissue mechanobiology in both healthy and injured tissues. Developing a model system to test t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffac73198af9eae83a251c99d83a6a5d
https://doi.org/10.1016/j.jbiomech.2012.10.018
https://doi.org/10.1016/j.jbiomech.2012.10.018
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 8:210-225
Human bone marrow-derived mesenchymal stem cells (hBM-MSCs) have potential clinical utility in the treatment of a multitude of ailments and diseases, due to their relative ease of isolation from patients and their capacity to form many cell types. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edbd70078288045ec94c217591597293
https://doi.org/10.1002/term.1515
https://doi.org/10.1002/term.1515
Publikováno v:
Computer Methods in Biomechanics and Biomedical Engineering. 14:1071-1077
Lower back pain due to intervertebral disc (IVD) degeneration is a prevalent problem which drastically affects the quality of life of millions of sufferers. Healthy IVDs begin with high populations of notochordal cells in the nucleus pulposus, while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792e32c3be6ca844723bcab81a211fa7
https://doi.org/10.1080/10255842.2010.508037
https://doi.org/10.1080/10255842.2010.508037
Autor:
J. Simon C. Arthur, Christopher J. Hunter, Kirsty J. Martin, Andrew D. Wingate, Carol Clacher, Julia M. Carr
Publikováno v:
genesis. 47:688-696
Phosphorylation of Ser133 in the transcription factor CREB is an important mechanism for regulating its transcriptional activity, however recent work has suggested significant roles for other regulatory inputs into CREB. To allow study of this in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf81b0e03fdbe5c89daf304e432ab980
https://doi.org/10.1002/dvg.20548
https://doi.org/10.1002/dvg.20548