Výsledky vyhledávání - "Christopher J. Hillard"

The Progesterone Receptor Hinge Region Regulates the Kinetics of Transcriptional Responses Through Acetylation, Phosphorylation, and Nuclear Retention

Autor: Lauren Czaplicki, Carol A. Lange, Andrea R. Daniel, Angela L. Gaviglio, Christopher J. Hillard, Daniel Housa

Publikováno v: Molecular Endocrinology. 24:2126-2138

Progesterone receptors (PRs) are critical regulators of mammary gland development and contributors to breast cancer progression. Posttranslational modifications of PR have been shown to alter hormone responsiveness. Site-directed mutagenesis demonstr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac168aa725ddb898b1b77d4d90e5714c
https://doi.org/10.1210/me.2010-0170

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Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors

Autor: Christopher J. Hillard, Andrea R. Daniel, Emily J. Faivre, Carol A. Lange

Publikováno v: Molecular endocrinology (Baltimore, Md.). 22(4)

Human progesterone receptors (PR) rapidly activate cytosolic signaling pathways, in addition to their classical function as ligand-activated transcription factors. Using ER+/PR-B+ T47D breast cancer cells, we probed the role of progestin-stimulated r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445d7cb8a5f79d9090a22365a59983fd
https://pubmed.ncbi.nlm.nih.gov/18202149

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Radio Frequency Therapy (Vanquish) Noninvasive Body Sculpting for Reduction of Abdominal Fat

Autor: Christopher J. Hillard, Ruth J. Barta, Morgan R. Betker, Cherrie A. Heinrich, Daniel Bernstein

Publikováno v: Plastic and Reconstructive Surgery. 136:130

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e44713a7f6dc79c2f090f36bcdb2e41b
https://doi.org/10.1097/01.prs.0000472444.62861.68

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Enhancing hepatic glycolysis reduces obesity: differential effects on lipogenesis depend on site of glycolytic modulation

Autor: David A. Okar, Honggui Li, Johnthomas Kang, Christopher J. Hillard, Salmaan A. Khan, Alex J. Lange, Chaodong Wu, Li Jen Peng

Publikováno v: Cell metabolism. 2(2)

SummaryReducing obesity requires an elevation of energy expenditure and/or a suppression of food intake. Here we show that enhancing hepatic glycolysis reduces body weight and adiposity in obese mice. Overexpression of glucokinase or 6-phosphofructo-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e627b7322412645114b6a96e1d35ae8b
https://pubmed.ncbi.nlm.nih.gov/16098830

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