Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Christopher J. Guerin"'
Autor:
Christopher J Guerin
Publikováno v:
Microscopy Today. 31:26-31
Immunohistochemistry (IHC) is the use of antibodies as probes to determine the localization of proteins in a cell or tissue sample. In microscopy, the technique has been in use since the 1940s by pathologists and research scientists. At first glance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a8bd97f14a9960e1d74356a814ebecf
https://doi.org/10.1093/mictod/qaad006
https://doi.org/10.1093/mictod/qaad006
Autor:
Lincoln T Shenje, Loren J Field, Catrin A Pritchard, Christopher J Guerin, Michael Rubart, Mark H Soonpaa, Keng-Leong Ang, Manuel Galiñanes
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1929 (2008)
Cultured cardiac explants produce a heterogeneous population of cells including a distinctive population of refractile cells described here as small round cardiac explant derived cells (EDCs). The aim of this study was to explore the source, morpholo
Externí odkaz:
https://doaj.org/article/993c4e93a7f24493841753436f9a0374
Autor:
David A. Pearce, Noreen A. Alexander, Subrata Chattopadhyay, Stephen J. A. Shemilt, Ming K. Lim, Jared W. Benedict, Jonathan D. Cooper, Christopher J. Guerin
Publikováno v:
Neurobiology of Disease, Vol 25, Iss 2, Pp 239-251 (2007)
Patients and a mouse model of Batten disease, the juvenile form of neuronal ceroid lipofuscinosis (JNCL), raise autoantibodies against GAD65 and other brain-directed antigens. Here we investigate the adaptive component of the neuroimmune response. Cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1922b0e51bee6ce32e4d74c595d139aa
https://doi.org/10.1016/j.nbd.2006.09.005
https://doi.org/10.1016/j.nbd.2006.09.005
Publikováno v:
Microscopy Research and Technique. 70:76-84
It is difficult to obtain precise quantitative measurements from fluorescent images captured from widefield microscopes. We wished to ascertain if reliable quantitative measurements of both biological and nonbiological specimens were possible using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5905f2262c2c3c9b07bdeebaf5ef743a
https://doi.org/10.1002/jemt.20389
https://doi.org/10.1002/jemt.20389
Autor:
Malcolm Prior, Timothy Lister, Sharon N. Reith, George Mavroudis, Colin L. Willis, David E. Ray, Christopher J. Guerin, Christopher C. Nolan
Publikováno v:
Glia. 45:325-337
Blood-brain barrier (BBB) breakdown is a feature of cerebral ischaemia, multiple sclerosis, and other neurodegenerative diseases, yet the relationship between astrocytes and the BBB integrity remains unclear. We present a simple in vivo model in whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759c0e5007b24741706e913197b976f6
https://doi.org/10.1002/glia.10333
https://doi.org/10.1002/glia.10333
Autor:
Jerry Yee, Patricia R. Segarini, Abdulkarim Sharba, Pedro Cortes, Stephanie Ladson-Wofford, Katie Drake, Bruce L. Riser, Mary E. Choi, Robert G. Narins, Christopher J. Guerin
Publikováno v:
Kidney International. 56:428-439
TGF-β receptor expression and binding in rat mesangial cells: Modulation by glucose and cyclic mechanical strain. Background Transforming growth factor-β (TGF-β) is a causal factor in experimental glomerulosclerosis, and it mediates the increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4447da6603764b568671a4cc276254b8
https://doi.org/10.1046/j.1523-1755.1999.00600.x
https://doi.org/10.1046/j.1523-1755.1999.00600.x
Publikováno v:
American Journal of Ophthalmology. 118:368-376
We examined the expression of several proteins normally present in Müller's glia after the production of experimental retinal detachment in adult cats. Retinas were detached for one-half to seven days, after which the tissue was processed for correl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8819cf0aee583d014a94c91f4567fe0
https://doi.org/10.1016/s0002-9394(14)72962-9
https://doi.org/10.1016/s0002-9394(14)72962-9
Autor:
Bruce A. Pfeffer, Kathleen C. Flanders, David Danielpour, Christopher J. Guerin, Don H. Anderson
Publikováno v:
Experimental Eye Research. 59:323-333
Several techniques were utilized to assess the levels, disposition and cellular sources of isoforms 1 and 2 of transforming growth factor beta (TGF-beta) in the posterior pole of the monkey eye. Freshly dissected tissues, as well as the saline vehicl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae79db62111dadae7962ea09137e55e
https://doi.org/10.1006/exer.1994.1114
https://doi.org/10.1006/exer.1994.1114
Background Transient receptor potential vanilloid subtype 1 (TRPV1) receptor is a primary pain-sensing relay at peripheral sensory nerve endings and is also widespread in the brain, where it is implicated in neurodegeneration. Previous studies of TRP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b34930c5c15b399059b4d571cc791e
Autor:
Bejal Gosai, Peter W. Andrew, Christopher O'Callaghan, Andrew Rutman, Robert A. Hirst, Christopher J. Guerin, Pierluigi Nicotera
Publikováno v:
The Journal of infectious diseases. 197(5)
BACKGROUND: The role played by pneumolysin and autolysin in pneumococcal meningitis is poorly understood. METHODS: A rat model was used to investigate the disease, in which surgical implantation of a cisternal catheter allowed bacterial instillation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c01b324cf3b35a196e3a1325b1f4169
https://pubmed.ncbi.nlm.nih.gov/18260758
https://pubmed.ncbi.nlm.nih.gov/18260758