Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christopher J. Goetz"'
Publikováno v:
Molecules, Vol 29, Iss 5, p 1185 (2024)
Sirtuins are NAD+-dependent protein deacylases and key metabolic regulators, coupling the cellular energy state with selective lysine deacylation to regulate many downstream cellular processes. Humans encode seven sirtuin isoforms (Sirt1-7) with dive
Externí odkaz:
https://doaj.org/article/93ab85f7301a4088977ecd173ca0670c
Autor:
Nikki Johnston, Tina L. Samuels, Christopher J. Goetz, Leggy A. Arnold, Brian C. Smith, Donna Seabloom, Beverly Wuertz, Frank Ondrey, Timothy S. Wiedmann, Nemanja Vuksanovic, Nicholas R. Silvaggi, Alexander C. MacKinnon, James Miller, Jonathan Bock, Joel H. Blumin
Publikováno v:
The Laryngoscope. 133
More than 20% of the US population suffers from laryngopharyngeal reflux. Although dietary/lifestyle modifications and alginates provide benefit to some, there is no gold standard medical therapy. Increasing evidence suggests that pepsin is partly, i
Autor:
Shifali Shishodia, Stefan G. Kathman, Daniel J. Sprague, Michael D. Olp, Steven B. Summers, Brian C. Smith, Sarah L. Wynia-Smith, Alexander V. Statsyuk, Ziyang Xu, Christopher J. Goetz
Publikováno v:
ACS Chem Biol
BRD4, a member of the bromodomain and extraterminal domain (BET) family, has emerged as a promising epigenetic target in cancer and inflammatory disorders. All reported BET family ligands bind within the bromodomain acetyl-lysine binding sites and co
Publikováno v:
Bioorg Chem
Sirtuins are NAD+-dependent protein deacylases that remove acyl modifications from acyl-lysine residues, resulting in essential cellular signaling. Recognized for their role in lifespan extension, humans encode seven sirtuin isoforms (Sirt1-7), and l
Publikováno v:
SPIE Proceedings.
In evaluating the lithography road maps for the semiconductor industry, the continued development of techniques to extend the utility of optical methods through the 64- and 256- Megabit device generations seems assured. These developments will drive
Conference
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