Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Christopher J. Frederickson"'
Autor:
Christopher J. Frederickson, David E. B. Fleming, Dan Asael, Mukhtiar Zaman, Randal Ferguson, Michaela G. Kaiser, Bryn D. Rankin, Kassia M. M. Schenkels, Andrew I. T. Hess, Andrianna R. Scott, Cathleen J. M. Frederickson, Jonathan K. Sinclair, Nicola M. Lowe
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
The aim of this study was to determine whether X-ray fluorescence spectrometry (XRF) could be used to detect changes in hair zinc concentration in response to a modest daily increase in zinc from the consumption of zinc biofortified wheat flour. This
Externí odkaz:
https://doaj.org/article/1657f6ff67844f9f8f598c2c79adeb46
Autor:
John K. Brooks, Ademir Franco, Richard B. Thompson, Daniel E. Biederman, Vandana Kumar, Sarah L.J. Michel, Jordan D. Pritts BS, Christopher J. Frederickson, Nasir Bashirelahi, Jeffery B. Price
Publikováno v:
Journal of Forensic Sciences. 67:1274-1279
Publikováno v:
Journal of Trace Elements in Medicine and Biology. 50:609-614
A variety of adverse health effects have been identified as resulting from zinc deficiency. Zinc supplementation may therefore be indicated for certain individuals or populations. A rapid and straightforward means of assessing zinc status in humans w
Autor:
Robert J. Radford, Maria Azrad, Stephen J. Lippard, Wendy Demark-Wahnefried, Daniel Y. Zhang, Christopher J. Frederickson
Publikováno v:
ACS Chemical Biology
Small-molecule fluorescent sensors are versatile agents for detecting mobile zinc in biology. Capitalizing on the abundance of validated mobile zinc probes, we devised a strategy for repurposing existing intensity-based sensors for quantitative appli
Determination of the Zinc Concentration in Human Fingernails by Laser-Induced Breakdown Spectroscopy
Publikováno v:
Physics Publications
The absolute concentration of Zn in human fingernail clippings was determined ex vivo using 1064 nm laser-induced breakdown spectroscopy and confirmed by speciated isotope dilution mass spectrometry. A nail testing protocol that sampled across the na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d4d9477b6b050d6837b5e2a9681287
https://scholar.uwindsor.ca/physicspub/184
https://scholar.uwindsor.ca/physicspub/184
Autor:
Leonard J. Giblin, Christopher J. Frederickson, Irina Korichneva, Richard B. Thompson, Sarah Libert, Rebecca A. Bozym, Fabrice Chimienti, Maryam Parviz, Wolfgang Maret, Yuan Li, Gunter W Gross
Publikováno v:
Experimental Biology and Medicine. 235:741-750
The zinc(II) ion has recently been implicated in a number of novel functions and pathologies in loci as diverse as the brain, retina, small intestine, prostate, heart, pancreas, and immune system. Zinc ions are a required nutrient but elevated concen
Autor:
Anthony F. Bentley, Cathleen J. Frederickson, Stephen J. Lippard, Christopher J. Chang, Leonard J. Giblin, Christopher J. Frederickson
Publikováno v:
Journal of Histochemistry & Cytochemistry. 54:311-316
We have used a new family of zinc-specific-responsive fluorescent dyes (ZPs) to study the sequestration and secretion of zinc from Paneth cells, which are located in the bases of the crypts of Lieberkühn within the rat small intestine. Vivid ZP fluo
Publikováno v:
Journal of Alzheimer's Disease. 8:155-160
Prior brain injury is a major risk factor in the development of Alzheimer's disease. This is true for traumatic brain injury, stroke or ischemic brain injury, and (more speculatively) for brain injury resulting from the hypo-perfusion-reperfusion in
Autor:
Carolyn C. Woodroofe, Stephen J. Lippard, Rafik Masalha, Christopher J. Frederickson, Katie R. Barnes
Publikováno v:
Chemistry & Biology. 11(12):1659-1666
SummaryEsterification of fluorescent biosensors is a common strategy used to trap probes within the cell. Zinpyr-1 (ZP1) is a fluorescein-based bright fluorescent sensor for divalent zinc that is cell permeable without prior modification. We describe
Autor:
Eric A. Bedell, Cathy J. Frederickson, Hong Z. Yin, Christopher J. Frederickson, John H. Weiss, Donald S. Prough, Stefano L. Sensi, Shawn C. Burdette, Ai Q. Truong-Tran, Stephen J. Lippard, Rengarajan V. Balaji
Publikováno v:
Journal of Neuroscience Methods. 139:79-89
During excitotoxic brain damage, injured neurons accumulate an anomalous, pathological burden of weakly bound, rapidly exchangeable Zn(2+) that diffusely fills the soma, nucleus and proximal dendrites. Mounting evidence indicates that this Zn(2+) is