Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christopher J. Folts"'
Autor:
Andrew Campbell, Jessica M. Hogestyn, Christopher J. Folts, Brittany Lopez, Christoph Pröschel, David Mock, Margot Mayer-Pröschel
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Progression of demyelinating diseases is caused by an imbalance of two opposing processes: persistent destruction of myelin and myelin repair by differentiating oligodendrocyte progenitor cells (OPCs). Repair that cannot keep pace with destr
Externí odkaz:
https://doaj.org/article/c31090ca82e3444daa7a868ec7878e14
Autor:
Stefanie Giera, Rong Luo, Yanqin Ying, Sarah D Ackerman, Sung-Jin Jeong, Hannah M Stoveken, Christopher J Folts, Christina A Welsh, Gregory G Tall, Beth Stevens, Kelly R Monk, Xianhua Piao
Publikováno v:
eLife, Vol 7 (2018)
In the central nervous system (CNS), myelin formation and repair are regulated by oligodendrocyte (OL) lineage cells, which sense and integrate signals from their environment, including from other glial cells and the extracellular matrix (ECM). The s
Externí odkaz:
https://doaj.org/article/df855cc93c824dc2a33053125a2dd7c0
Autor:
Stefanie Giera, Christopher J. Folts, Priya Kishore, Chuang Gao, Xianhua Piao, Brian Chiou, Hayeon C. Oak, Diankun Yu, Rongcai Jiang
Publikováno v:
Glia. 69:413-423
Myelination of axons in the central nervous system (CNS) is a concerted effort between many cell types, resulting in significant cross-talk and communication among cells. Adhesion G protein-coupled receptor ADGRG1 (GPR56) is expressed in all major gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c55c4db69c9d093a6a8cc31dda60339
https://doi.org/10.1002/glia.23906
https://doi.org/10.1002/glia.23906
Publikováno v:
Trends in Pharmacological Sciences. 40:278-293
The family of adhesion G protein-coupled receptors (aGPCRs) consists of 33 members in humans. Although the majority continue to be orphan receptors with unknown functions, many reports have demonstrated critical functions for some members of this fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f33f199700ff6cc6a1af6c26ab75d9
https://doi.org/10.1016/j.tips.2019.02.003
https://doi.org/10.1016/j.tips.2019.02.003
Publikováno v:
Neural Regeneration Research
This review addresses two puzzling findings related to mutations in galactocerebrosidase (GALC) that cause Krabbe disease (KD), a severe lysosomal storage disorder characterized by extensive myelin damage in children with mutations in both GALC allel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ecaad9fa0e461a3d9e217ea87e6ee9
http://europepmc.org/articles/PMC5900492
http://europepmc.org/articles/PMC5900492
Autor:
Mark Noble, Christopher J. Folts, Nicole Scott-Hewitt, Gavin Piester, Margot Mayer-Pröschel, Jessica M Hogestyn
Publikováno v:
Human Molecular Genetics. 26:2825-2837
Genome-wide association studies are identifying multiple genetic risk factors for several diseases, but the functional role of these changes remains mostly unknown. Variants in the galactocerebrosidase (GALC) gene, for example, were identified as a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf2e2437bb19b17888c404aa07f02d2
https://doi.org/10.1093/hmg/ddx153
https://doi.org/10.1093/hmg/ddx153
Autor:
Xianhua Piao, Christina A. Welsh, Rong Luo, Sung-Jin Jeong, Yanqin Ying, Kelly R. Monk, Beth Stevens, Hannah M. Stoveken, Christopher J. Folts, Sarah D. Ackerman, Gregory G. Tall, Stefanie Giera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6ade37b47477d50fe927c124f12735f
https://doi.org/10.7554/elife.33385.019
https://doi.org/10.7554/elife.33385.019
Autor:
Rong Luo, Yanqin Ying, Christina A. Welsh, Sarah D. Ackerman, Beth Stevens, Sung Jin Jeong, Gregory G. Tall, Hannah M. Stoveken, Kelly R. Monk, Christopher J. Folts, Stefanie Giera, Xianhua Piao
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
In the central nervous system (CNS), myelin formation and repair are regulated by oligodendrocyte (OL) lineage cells, which sense and integrate signals from their environment, including from other glial cells and the extracellular matrix (ECM). The s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a135810ae9b67605d99d19e13844e0e
http://europepmc.org/articles/PMC5980231
http://europepmc.org/articles/PMC5980231
Autor:
Brittany Lopez, Jessica M Hogestyn, David J. Mock, Christopher J. Folts, Christoph Pröschel, Andrew Campbell, Margot Mayer-Pröschel
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Progression of demyelinating diseases is caused by an imbalance of two opposing processes: persistent destruction of myelin and myelin repair by differentiating oligodendrocyte progenitor cells (OPCs). Repair that cannot keep pace with destruction re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b265604aa151542ec4da3066d11066f3
https://doi.org/10.1038/s41598-017-04432-y
https://doi.org/10.1038/s41598-017-04432-y
Autor:
Nicole Scott-Hewitt, Margot Mayer-Pröschel, Christoph Pröschel, Mark Noble, Christopher J. Folts
Publikováno v:
PLoS Biology, Vol 14, Iss 12, p e1002583 (2016)
PLoS Biology
PLoS Biology
Neurodegenerative lysosomal storage disorders (LSDs) are severe and untreatable, and mechanisms underlying cellular dysfunction are poorly understood. We found that toxic lipids relevant to three different LSDs disrupt multiple lysosomal and other ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e0473449af3d54ecf8818a6cdf54f9
http://europepmc.org/articles/PMC5169359?pdf=render
http://europepmc.org/articles/PMC5169359?pdf=render