Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Christopher J. Fielding"'
Autor:
Thomas A. Spencer, Pingzhen Wang, Dansu Li, Jonathon S. Russel, David H. Blank, Jarkko Huuskonen, Phoebe E. Fielding, Christopher J. Fielding
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 8, Pp 1510-1518 (2004)
Eight analogs of cholesterol (1) containing a benzophenone group have been synthesized as prospective photoaffinity labels for studies in cellular sterol efflux and HDL formation. Six of these compounds (4–9) have the photophore replacing different
Externí odkaz:
https://doaj.org/article/5c714381120b4896b8510939e5096a9b
Publikováno v:
High-Density Lipoproteins: From Basic Biology to Clinical Aspects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::893710a20d40d124f0b5b075b01277bb
https://doi.org/10.1002/9783527625178.ch6
https://doi.org/10.1002/9783527625178.ch6
Autor:
Eleni E. Zanni, Angeliki Papapanagiotou, Angeliki Chroni, Christopher J. Fielding, Dimitris Kardassis, Vassilis I. Zannis
Publikováno v:
High-Density Lipoproteins: From Basic Biology to Clinical Aspects
Human plasma apoA-I is a 243-residue protein that originates from a 249-aa precursor synthesized and secreted primarily by the liver and the intestine [1]. ApoA-I is themajor protein component ofHDLand is essential for the biogenesis and the function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f1d0bf0be6e4eee1124ba554f21f35d
https://doi.org/10.1002/9783527625178.ch11
https://doi.org/10.1002/9783527625178.ch11
Publikováno v:
Biochemistry. 45:15068-15074
The liver X receptor (LXR) agonist TO901317 inhibited the synthesis of apolipoprotein A1 (apo A1) by human liver-derived cells, including the formation of lipid-poor, prebeta-migrating high-density lipoprotein (HDL). Despite activation of the lipid t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c9076bdeabff599351c0f978a65f5e
https://doi.org/10.1021/bi061378y
https://doi.org/10.1021/bi061378y
Autor:
Ithan D. Peltan, Thomas A. Spencer, Pingzhen Wang, Janeta Popovici-Muller, Christopher J. Fielding, Phoebe E. Fielding
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:3000-3004
Syntheses are described of fatty acid analogs 5 and 6, and cholesterol (2) analogs 7 and 8 containing fluorenone groups, which are both photoactivable and fluorescent. The potential of the analogs of 2 as biochemical research tools has been demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31ddf3fe5e5ef8b6cbd7c9009bdb7a5
https://doi.org/10.1016/j.bmcl.2006.02.061
https://doi.org/10.1016/j.bmcl.2006.02.061
Publikováno v:
Lipid Rafts and Caveolae: From Membrane Biophysics to Cell Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80f9c026a42cf4a807b07e6db8d2086c
https://doi.org/10.1002/3527608079.ch5
https://doi.org/10.1002/3527608079.ch5
Autor:
Leila Kotite, Yasushi Nakamura, Thomas A. Spencer, Christopher J. Fielding, Yonghong Gan, Phoebe E. Fielding
Publikováno v:
Biochemistry. 43:14811-14820
A 70-75 kDa high-density lipoprotein (HDL) particle with pre-beta-electrophoretic migration (pre-beta(1)-HDL) has been identified in several studies as an early acceptor of cell-derived cholesterol. However, the further metabolism of this complex has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8c223086d1b87c3634f49b39421362
https://doi.org/10.1021/bi0485629
https://doi.org/10.1021/bi0485629
Autor:
Jonathon S. Russel, Christopher J. Fielding, Pingzhen Wang, Phoebe E. Fielding, Jarkko Huuskonen, Dansu Li, David H. Blank, Thomas A. Spencer
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 8, Pp 1510-1518 (2004)
Eight analogs of cholesterol (1) containing a benzophenone group have been synthesized as prospective photoaffinity labels for studies in cellular sterol efflux and HDL formation. Six of these compounds (4-9) have the photophore replacing different p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d52ff316d1f56673499c44f1a251dc5
http://www.sciencedirect.com/science/article/pii/S0022227520313134
http://www.sciencedirect.com/science/article/pii/S0022227520313134
Autor:
Christopher J. Fielding
Publikováno v:
International Congress Series. 1262:396-399
Caveolae are free cholesterol-rich invaginated microdomains of the cell surface characterized by the presence of one or more structural proteins (caveolins). The cholesterol-binding capacity of caveolin plays a key role in the organization of signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1313beb6330a7c83c1aba0d342b77376
https://doi.org/10.1016/j.ics.2003.12.023
https://doi.org/10.1016/j.ics.2003.12.023
Publikováno v:
Biochemistry. 43:2578-2586
In human vascular smooth muscle cells, inhibitors of protein kinase C activity reduced serine phosphorylation of caveolin-1 and increased sterol binding by this protein. This was measured after immunoprecipitation of caveolin-1 from cells labeled wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8fee66db347abe4e2207d6363348992
https://doi.org/10.1021/bi035442c
https://doi.org/10.1021/bi035442c