Potential use of serum-derived bovine immunoglobulin/protein isolate for the management of COVID-19

Autor: Moises Contreras, Shahin Gharakhanian, Netanya S. Utay, David M. Asmuth, Christopher J. Detzel, Christopher D. Warner

Publikováno v: Drug development research. 82(7)

COVID-19 manifests as a mild disease in most people but can progress to severe disease in nearly 20% of individuals. Disease progression is likely driven by a cytokine storm, either directly stimulated by SARS-CoV-2 or by increased systemic inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641625fc1d6639bfae3e98c05d0c196b
https://pubmed.ncbi.nlm.nih.gov/34110032

Comparison of the amino acid and peptide composition and postprandial response of beef, hydrolyzed chicken, and whey protein nutritional preparations

Autor: Christopher J. Detzel, Bryon W. Petschow, Nicole Johnson, Eric M. Weaver

Publikováno v: Functional Foods in Health and Disease, Vol 6, Iss 10, Pp 612-626 (2016)

Background: Increasing dietary protein intake synergistically improves the effect of exercise to stimulate muscle protein synthesis. The purpose of this study was to evaluate the plasma amino acid response of two novel protein nutritional preparation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::957d80057ce73d33dde34a1feb0d907e
http://www.ffhdj.com/index.php/ffhd/article/view/308/537

Evaluation of oral serum-derived bovine immunoglobulins in HIV-infected patients with chronic idiopathic diarrhea

Autor: Audrey L. Shaw, Carl J. Fichtenbaum, Bryon W. Petschow, Eric M. Weaver, Ma Somsouk, Netanya S. Utay, David M. Asmuth, Anthony LaMarca, John Hinkle, Christopher J. Detzel

Publikováno v: Asmuth, DM; Hinkle, JE; LaMarca, A; Fichtenbaum, CJ; Somsouk, M; Utay, NS; et al.(2017). Evaluation of oral serum-derived bovine immunoglobulins in HIV-infected patients with chronic idiopathic diarrhea. HIV Clinical Trials, 18(5-6), 205-213. doi: 10.1080/15284336.2017.1401256. UCSF: Retrieved from: http://www.escholarship.org/uc/item/19601066

© 2017 Informa UK Limited, trading as Taylor & Francis Group. Objectives: To evaluate serum-derived bovine immunoglobulin/protein isolate (SBI) for safety and impact on gastrointestinal (GI) symptoms in HIV patients with chronic idiopathic diarrhea.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c182d8e42cdff51e6d5df4f184e8ae47
http://www.escholarship.org/uc/item/19601066

A study of the Coriolis effect on the fluid flow profile in a centrifugal bioreactor

Autor: Christopher J. Detzel, Bernard J. Van Wie, Cornelius F. Ivory, Michael R. Thorson

Publikováno v: Biotechnology Progress. 25:1025-1034

Increasing demand for tissues, proteins, and antibodies derived from cell culture is necessitating the development and implementation of high cell density bioreactors. A system for studying high density culture is the centrifugal bioreactor (CCBR), w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6a5607ba1d87a1da113e490c7f22a9
https://doi.org/10.1002/btpr.183

Bovine immunoglobulin/protein isolate binds pro-inflammatory bacterial compounds and prevents immune activation in an intestinal co-culture model

Autor: Bryon W. Petschow, Alan Horgan, Eric M. Weaver, Abigail Henderson, Christopher D. Warner, Christopher J. Detzel, Kenneth J. Maas

Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0120278 (2015)
PLoS ONE

Intestinal barrier dysfunction is associated with chronic gastrointestinal tract inflammation and diseases such as IBD and IBS. Serum-derived bovine immunoglobulin/protein isolate (SBI) is a specially formulated protein preparation (>90%) for oral ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef399d140fbd4fd1d08c7037b453c9a
http://europepmc.org/articles/PMC4382133?pdf=render