Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christopher J. Del Nagro"'
Autor:
Cheng-Ping Mao, Martin R Brovarney, Karim Dabbagh, Herbert F Birnböck, Wolfgang F Richter, Christopher J Del Nagro
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80533 (2013)
The CD20-specific monoclonal antibody rituximab (MabThera(®), Rituxan(®)) is widely used as the backbone of treatment for patients with hematologic disorders. Intravenous administration of rituximab is associated with infusion times of 4-6 hours, a
Externí odkaz:
https://doaj.org/article/eeb65fc96d514282b864a98a108fedec
Autor:
Martin Schwickart, Meina Liang, Lorin Roskos, Nathan Standifer, Christopher J. Del Nagro, Inna Vainshtein, Amy Schneider
Publikováno v:
Cytometry. Part B, Clinical Cytometry
Receptor occupancy (RO) assays are designed to quantify the binding of therapeutics to their targets on the cell surface and are frequently used to generate pharmacodynamic (PD) biomarker data in nonclinical and clinical studies of biopharmaceuticals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf8af4507b8aecda791d3246050b37e
http://europepmc.org/articles/PMC5042057
http://europepmc.org/articles/PMC5042057
Autor:
Matthew H. Cato, Hart S. Dengler, Christopher J. Del Nagro, Cecille D. Browne, Robert C. Rickert
Publikováno v:
Immunity. 31(5):749-760
SummaryAnergy is a critical physiologic mechanism to censor self-reactive B cells. However, a biochemical understanding of how anergy is achieved and maintained is lacking. Herein, we investigated the role of the phosphoinositide 3-kinase (PI3K) lipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f73c371f7c00d4a8878086e2f5a447
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 175(8)
Complement C3 cleavage products mediate the recognition and clearance of toxic or infectious agents. In addition, binding of the C3d fragment to Ag promotes B lymphocyte activation through coengagment of the BCR and complement receptor 2 (CD21). Sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9752e9a840101369d14d4d398ac2495d
https://pubmed.ncbi.nlm.nih.gov/16210644
https://pubmed.ncbi.nlm.nih.gov/16210644
Autor:
Sidne A. Omori, Robert C. Rickert, Amy N Anzelon, Christopher J. Del Nagro, Ravi Kolla, Dennis C Otero
Publikováno v:
Immunologic research. 31(2)
Although the B-cell antigen receptor (BCR) factors most prominently in the maintenance and differentiation of mature B cells, it is now appreciated that co-receptor molecules can positively or negatively modulate signals through the BCR. Co-receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99fa3b8572ee0833226df365d40196c8
https://pubmed.ncbi.nlm.nih.gov/15778510
https://pubmed.ncbi.nlm.nih.gov/15778510