Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christopher J. D. Sinclair"'
Autor:
Norman J. Haughey, Fiona E. Parkinson, T. Othman, Christopher J. D. Sinclair, Jonathan D. Geiger
Publikováno v:
Neuropharmacology. 43:836-846
In the brain, the levels of adenosine increase up to 100-fold during cerebral ischernia; however, the roles of specific cell types, enzymatic pathways and membrane transport processes in regulating intra- and extracellular concentrations of adenosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2644e1f083bac3adadad6d1513a936
https://doi.org/10.1016/s0028-3908(02)00083-7
https://doi.org/10.1016/s0028-3908(02)00083-7
Autor:
Timothy Othman, Christopher J. D. Sinclair, Norman J. Haughey, Jonathan D. Geiger, Fiona E. Parkinson
Publikováno v:
Neurochemical Research. 27:289-296
Glutamate is the primary excitatory neurotransmitter in brain. By stimulating neuronal activity, glutamate increases cellular energy utilization, enhances ATP hydrolysis and promotes the formation of adenosine. Adenosine has receptor-mediated effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ec366738a7be45d7c277c2648c04f0f
https://doi.org/10.1023/a:1014955111742
https://doi.org/10.1023/a:1014955111742
Autor:
Fiona E. Parkinson, Kathe A. Stanness, Ljiljana Krizanac-Bengez, Christopher J. D. Sinclair, Darnir Janigro
Publikováno v:
Brain Research. 898:122-125
Adenosine is an inhibitory neuromodulator in the central nervous system and has been reported to have neuroprotective properties. Using a dynamic in vitro blood-brain barrier, we investigated the hypothesis that inhibition of adenosine transporters o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b7da3d2fcab470928bb481b0a484c5
https://doi.org/10.1016/s0006-8993(01)02175-8
https://doi.org/10.1016/s0006-8993(01)02175-8
Publikováno v:
Biochemical Pharmacology. 59:477-483
Adenosine is produced intracellularly during conditions of metabolic stress and is an endogenous agonist for four subtypes of G-protein linked receptors. Nucleoside transporters are membrane-bound carrier proteins that transfer adenosine, and other n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e255f84b0651422ff029a1a477cb06
https://doi.org/10.1016/s0006-2952(99)00350-0
https://doi.org/10.1016/s0006-2952(99)00350-0
Autor:
Ana Hanlon-Dearman, Christopher J. D. Sinclair, Shayne Taback, William Craig, Michael E. K. Moffatt
Publikováno v:
The Cochrane Library
Scopus-Elsevier
Scopus-Elsevier
Background Gastro-esophageal reflux (GER) is the refluxing of gastric contents into the esophagus. Fifty per cent of all infants 0 to 3 months regurgitate at least once a day. This drops to 5% once infants are 10 to 12 months old. Three per cent of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3282ef81707a6910586740e93f0f25e
https://doi.org/10.1002/14651858.cd003502.pub3
https://doi.org/10.1002/14651858.cd003502.pub3
Autor:
Timothy, Othman, Christopher J D, Sinclair, Norman, Haughey, Jonathan D, Geiger, Fiona E, Parkinson
Publikováno v:
Neurochemical research. 27(4)
Glutamate is the primary excitatory neurotransmitter in brain. By stimulating neuronal activity, glutamate increases cellular energy utilization, enhances ATP hydrolysis and promotes the formation of adenosine. Adenosine has receptor-mediated effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::549bb14920780b47df7f80632786e2e2
https://pubmed.ncbi.nlm.nih.gov/11958530
https://pubmed.ncbi.nlm.nih.gov/11958530
Autor:
Jonathan D. Geiger, Norman J. Haughey, Christopher J. D. Sinclair, T. Othman, Fiona E. Parkinson
Publikováno v:
Neuropharmacology. 44:155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7389f2577e6a17cf4bd0953d5fb8297
https://doi.org/10.1016/s0028-3908(02)00362-3
https://doi.org/10.1016/s0028-3908(02)00362-3