Zobrazeno 1 - 10
of 667
pro vyhledávání: '"Christopher J. Moody"'
Autor:
Maysaa M. Saleh, Duaa A. Abuarqoub, Alaa M. Hammad, Md Shahadat Hossan, Najneen Ahmed, Nazneen Aslam, Abdallah Y. Naser, Christopher J. Moody, Charles A. Laughton, Tracey D. Bradshaw
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 1, Pp 175-196 (2022)
Here, we describe the anticancer activity of our novel bis-triazoles MS47 and MS49, developed previously as G-quadruplex stabilizers, focusing specifically upon the human melanoma MDA-MB-435 cell line. At the National Cancer Institute (NCI), USA, bis
Externí odkaz:
https://doaj.org/article/29394440f6aa4e28ab41123f12ea813e
Autor:
Helen S. Summers, William Lewis, Huw E.L. Williams, Tracey D. Bradshaw, Christopher J. Moody, Malcolm F.G. Stevens
Publikováno v:
European Journal of Medicinal Chemistry. :115507
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18bcc5ad95acda3eead7aa69695b9bc7
https://doi.org/10.1016/j.ejmech.2023.115507
https://doi.org/10.1016/j.ejmech.2023.115507
Autor:
Christopher J. Moody, Malcolm F. G. Stevens, Helen S. Summers, Magdalena B. Foreiter, Tracey D. Bradshaw, William Lewis
Publikováno v:
Arkivoc. 2020:36-45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bba9060b878af1f9c4f535b689171da
https://doi.org/10.24820/ark.5550190.p011.182
https://doi.org/10.24820/ark.5550190.p011.182
Autor:
Helen S. Summers, Tracey D. Bradshaw, Christopher J. Moody, Nicola Weston, Lyudmila Turyanska, Marianne Ashford, Malcolm F. G. Stevens, Kaouthar Bouzinab, Neil R. Thomas, Pavel Gershkovich
Publikováno v:
ACS Applied Materials & Interfaces. 12:12609-12617
Glioblastoma multiforme (GBM) is a grade IV astrocytoma, which is the most aggressive form of brain tumor. The standard of care for this disease includes surgery, radiotherapy and temozolomide (TMZ) chemotherapy. Poor accumulation of TMZ at the tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a444ce4c13df6bd9409224878cf254
https://doi.org/10.1021/acsami.0c01514
https://doi.org/10.1021/acsami.0c01514
Autor:
Patricio Sánchez, Cristian O. Salas, Sebastián Gallardo‐Fuentes, Alondra Villegas, Nicolás Veloso, Jessica Honores, Martyn Inman, Mauricio Isaacs, Renato Contreras, Christopher J. Moody, Jonathan Cisterna, Iván Brito, Ricardo A. Tapia
Publikováno v:
Chemistrybiodiversity. 19(6)
The successful application of fragment-based drug discovery strategy for the efficient synthesis of phenoxy- or phenylamino-2-phenyl-benzofuran, -benzoxazole and -benzothiazole quinones is described. Interestingly, in the final step of the synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d95c103b8e1916ad63b8e5315f45d9b
https://pubmed.ncbi.nlm.nih.gov/35581163
https://pubmed.ncbi.nlm.nih.gov/35581163
Autor:
Anqi Yao, Sarah J. Storr, Martyn Inman, Lucy Barwell, Christopher J. Moody, Stewart G. Martin
The thioredoxin (Trx) system, a key antioxidant pathway, represents an attractive target for cancer therapy. This study investigated the chemotherapeutic and radiosensitising effects of a novel Trx reductase (TrxR) inhibitor, IQ10, on brain cancer ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f956d820084334886a12bfffb6073cda
https://doi.org/10.21203/rs.3.rs-987333/v1
https://doi.org/10.21203/rs.3.rs-987333/v1
Autor:
Anqi, Yao, Sarah J, Storr, Martyn, Inman, Lucy, Barwell, Christopher J, Moody, Stewart G, Martin
Publikováno v:
Molecular neurobiology. 59(6)
The thioredoxin (Trx) system, a key antioxidant pathway, represents an attractive target for cancer therapy. This study investigated the chemotherapeutic and radiosensitising effects of a novel Trx reductase (TrxR) inhibitor, IQ10, on brain cancer ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fdac66228a143091e793e4b984d18770
https://pubmed.ncbi.nlm.nih.gov/35344158
https://pubmed.ncbi.nlm.nih.gov/35344158
Publikováno v:
ARKIVOC, Vol 2007, Iss 11, Pp 56-63 (2006)
Externí odkaz:
https://doaj.org/article/c3f4b5d2eadc48168b7bf168ca9a6122
Publikováno v:
ARKIVOC, Vol 2002, Iss 8, Pp 16-33 (2002)
Externí odkaz:
https://doaj.org/article/52dde512973b4f33b6e88580068af2fe
Autor:
Shuping Dong, Yolanda Sanchez, Tindy Li, Claudia E. Murar, Anthony J. Wilson, Brent W. Mccleland, Hongwei Qi, Patricia L. Podolin, Marc Galop, Christopher J. Moody, Hongxing Yan, John Yonchuk, Roderick S. Davis, Alan P. Graves, Catherine Booth-Genthe, Joseph P. Foley, Jen-Pyng Kou, Jeffrey K. Kerns, Brian Bolognese, James F. Callahan, Mary Mentzer, Lawrence Wolfe, Jeffrey C. Boehm, Robin Carr
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:579-588
The antioxidant natural product sulforaphane (SFN) is an oil with poor aqueous and thermal stability. Recent work with SFN has sought to optimize methods of formulation for oral and topical administration. Herein we report the design of new analogs o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b415f7b6666ea7f677038e87013d3b1
https://doi.org/10.1016/j.bmc.2018.12.026
https://doi.org/10.1016/j.bmc.2018.12.026