Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Christopher J Wilds"'
Autor:
Guennadi Kozlov, Jianning Jiang, Tyler Rutherford, Anne M. Noronha, Christopher J. Wilds, Kalle Gehring
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 764-773 (2024)
La-related proteins (LARPs) are a family of RNA-binding proteins that share a conserved La motif (LaM) domain. LARP1 plays a role in regulating ribosomal protein synthesis and stabilizing mRNAs and has a unique structure without an RNA binding RRM do
Externí odkaz:
https://doaj.org/article/6b6546ccc14b42b59f428ad7279add2a
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 908-931 (2021)
Over the past 25 years, the acceleration of achievements in the development of oligonucleotide-based therapeutics has resulted in numerous new drugs making it to the market for the treatment of various diseases. Oligonucleotides with alterations to t
Externí odkaz:
https://doaj.org/article/48482f334881480e8d600f8d47f6f6c8
Publikováno v:
ChemBioChem. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d827723bd56ed50abe1bab76fb551dc9
https://doi.org/10.1002/cbic.202300068
https://doi.org/10.1002/cbic.202300068
Publikováno v:
Current Protocols. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54ba76766f174f357fce7eca36c378ef
https://doi.org/10.1002/cpz1.691
https://doi.org/10.1002/cpz1.691
Publikováno v:
Chemical Science. 13:410-420
A breadth of strategies are needed to efficiently modify oligonucleotides with peptides or lipids to capitalize on their therapeutic and diagnostic potential, including the modulation of in vivo chemical stability and for applications in cell-targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea562335eebcae1ecca6fcf5da67c13b
https://doi.org/10.1039/d1sc04937b
https://doi.org/10.1039/d1sc04937b
Autor:
Guennadi Kozlov, Sandy Mattijssen, Jianning Jiang, Samuel Nyandwi, Tara Sprules, James R Iben, Steven L Coon, Sergei Gaidamakov, Anne M Noronha, Christopher J Wilds, Richard J Maraia, Kalle Gehring
Publikováno v:
Nucleic acids research. 50(16)
La-related proteins (LARPs) comprise a family of RNA-binding proteins involved in a wide range of posttranscriptional regulatory activities. LARPs share a unique tandem of two RNA-binding domains, La motif (LaM) and RNA recognition motif (RRM), toget
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37717c15758c06e0ab5cdf66c9afe7a9
https://pubmed.ncbi.nlm.nih.gov/35979957
https://pubmed.ncbi.nlm.nih.gov/35979957
Autor:
Kieran Duke, Gabrielle A. Mandl, Christopher Liczner, John A. Capobianco, Christopher J. Wilds, Steven L. Maurizio
Publikováno v:
Materials Chemistry Frontiers. 5:4690-4699
Photo-mediated systems present a highly attractive route for controlling the intracellular delivery of their cargo. Of particular interest, oligonucleotides are a promising class of molecule that are highly versatile for intracellular applications, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ff7ec0ffbc00fb1e3ae285d85be898b
https://doi.org/10.1039/d1qm00467k
https://doi.org/10.1039/d1qm00467k
Publikováno v:
ChemistrySelect. 5:15020-15027
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e7b8798bf0ea38670ed2ea71f951345
https://doi.org/10.1002/slct.202003893
https://doi.org/10.1002/slct.202003893
Autor:
J. L. Marignier, J. R. Wagner, Darel J. Hunting, M. Mostafavi, Christopher J. Wilds, A. M. Noronha, B. Behmand, Léon Sanche
Publikováno v:
Journal of Radiation Research
Double-stranded oligonucleotides containing cisplatin adducts, with and without a mismatched region, were exposed to hydrated electrons generated by gamma-rays. Gel electrophoresis analysis demonstrates the formation of cisplatin-interstrand crosslin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097064fab01b8d66e8ab5e74a6ad5e51
https://doi.org/10.1093/jrr/rraa014
https://doi.org/10.1093/jrr/rraa014
Publikováno v:
Bioorganicmedicinal chemistry letters. 67
The promise of the antisense approach to treat a variety of diseases with oligonucleotides and solutions to challenges that have been encountered in their development is attributable to chemical modification of the nucleic acid scaffold. Herein, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5acce3920486ea772e4572460660f54
https://pubmed.ncbi.nlm.nih.gov/35452799
https://pubmed.ncbi.nlm.nih.gov/35452799