Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Christopher J Walker"'
Autor:
Sonam Mittal, Ishaque Pulikkal Kadamberi, Hua Chang, Feng Wang, Sudhir Kumar, Shirng-Wern Tsaih, Christopher J. Walker, Pradeep Chaluvally-Raghavan, John Charlson, Yosef Landesman, Sunila Pradeep
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-6 (2023)
Abstract Leiomyosarcoma (LMS) is a rare soft tissue sarcoma (STS) that begins in smooth muscle tissue and most often initiates in the abdomen or uterus. Compared with other uterine cancers, uterine LMS (ULMS) is an aggressive tumor with poor prognosi
Externí odkaz:
https://doaj.org/article/91fda5397a8d4c568f9244b8871df4be
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Competent T-cells with sufficient levels of fitness combat cancer formation and progression. In multiple myeloma (MM), T-cell exhaustion is caused by several factors including tumor burden, constant immune activation due to chronic disease, age, nutr
Externí odkaz:
https://doaj.org/article/ba51e21c53824109807983fc6abda806
Autor:
Christopher J. Walker, Hua Chang, Leah Henegar, Trinayan Kashyap, Sharon Shacham, Josh Sommer, Michael J. Wick, Joan Levy, Yosef Landesman
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Chordoma is a rare cancer that grows in the base of the skull and along the mobile spine from remnants of embryonic notochord tissue. The cornerstone of current treatments is surgical excision with adjuvant radiation therapy, although complete surgic
Externí odkaz:
https://doaj.org/article/2439b9474a294b25943651078e71961a
Publikováno v:
IEEE Access, Vol 8, Pp 188825-188832 (2020)
This paper presents a low-loss surface mountable suspended integrated strip-line (SISL) technology. A DC-20 GHz thru transmission line and an eleventh-order generalized Chebyshev lowpass filter (LPF), with a cutoff frequency of 18 GHz, are simulated,
Externí odkaz:
https://doaj.org/article/099091b217ed4bb299b1fdaf2e818bee
Autor:
Jack G. Fisher, Christopher J. Walker, Amber DP. Doyle, Peter WM. Johnson, Francesco Forconi, Mark S. Cragg, Yosef Landesman, Salim. I. Khakoo, Matthew D. Blunt
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Selinexor is an FDA approved selective inhibitor of the nuclear export protein exportin-1 (XPO1) and causes specific cancer cell death via nuclear accumulation of tumor suppressor proteins. Design of rational studies for the use of selinexor in combi
Externí odkaz:
https://doaj.org/article/3bc2ec99a6694182a242490b99350987
Autor:
Katherine G. English, Andrea L. Reid, Adrienne Samani, Gerald J. F. Coulis, S. Armando Villalta, Christopher J. Walker, Sharon Tamir, Matthew S. Alexander
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2400 (2022)
Duchenne muscular dystrophy (DMD) is a progressive, X-linked childhood neuromuscular disorder that results from loss-of-function mutations in the DYSTROPHIN gene. DMD patients exhibit muscle necrosis, cardiomyopathy, respiratory failure, and loss of
Externí odkaz:
https://doaj.org/article/cd96cf6ba33a4262969160f2fc12b359
Autor:
Dimitrios Papaioannou, Hatice G. Ozer, Deedra Nicolet, Amog P. Urs, Tobias Herold, Krzysztof Mrózek, Aarif M.N. Batcha, Klaus H. Metzeler, Ayse S. Yilmaz, Stefano Volinia, Marius Bill, Jessica Kohlschmidt, Maciej Pietrzak, Christopher J. Walker, Andrew J. Carroll, Jan Braess, Bayard L. Powell, Ann-Kathrin Eisfeld, Geoffrey L. Uy, Eunice S. Wang, Jonathan E. Kolitz, Richard M. Stone, Wolfgang Hiddemann, John C. Byrd, Clara D. Bloomfield, Ramiro Garzon
Publikováno v:
Haematologica, Vol 107, Iss 5 (2021)
Expression levels of long non-coding RNA (lncRNA) have been shown to associate with clinical outcome of patients with cytogenetically normal acute myeloid leukemia (CN-AML). However, the frequency and clinical significance of genetic variants in the
Externí odkaz:
https://doaj.org/article/7f9bf447eead48ccb2195be68f8f7b08
Autor:
Dimitrios Papaioannou, Andreas Petri, Oliver M. Dovey, Sara Terreri, Eric Wang, Frances A. Collins, Lauren A. Woodward, Allison E. Walker, Deedra Nicolet, Felice Pepe, Prasanthi Kumchala, Marius Bill, Christopher J. Walker, Malith Karunasiri, Krzysztof Mrózek, Miranda L. Gardner, Virginia Camilotto, Nina Zitzer, Jonathan L. Cooper, Xiongwei Cai, Xiaoqing Rong-Mullins, Jessica Kohlschmidt, Kellie J. Archer, Michael A. Freitas, Yi Zheng, Robert J. Lee, Iannis Aifantis, George Vassiliou, Guramrit Singh, Sakari Kauppinen, Clara D. Bloomfield, Adrienne M. Dorrance, Ramiro Garzon
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
LncRNAs at the HOX gene locus are increased in expression in NPM1 mutant acute myeloid leukemia. In this study, the authors show that one such lncRNA, HOX3B-AS3, has a role in regulating gene transcription and protein synthesis in leukemia cells.
Externí odkaz:
https://doaj.org/article/4362506e0cc14ab88f90e66fd4195bb2
Autor:
Marius Bill, Deedra Nicolet, Jessica Kohlschmidt, Christopher J. Walker, Krzysztof Mrózek, Ann-Kathrin Eisfeld, Dimitrios Papaioannou, Xiaoqing Rong-Mullins, Zachary Brannan, Jonathan E. Kolitz, Bayard L. Powell, Kellie J. Archer, Adrienne M. Dorrance, Andrew J. Carroll, Richard M. Stone, John C. Byrd, Ramiro Garzon, Clara D. Bloomfield
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Leukemia stem cells (LSC) are more resistant to standard chemotherapy and their persistence during remission can cause relapse, which is still one of the major clinical challenges in the treatment of acute myeloid leukemia (AML). A better understandi
Externí odkaz:
https://doaj.org/article/163b6fd50bee4ae78efe618cb9abc265
Autor:
Michael P. Ozga, Deedra Nicolet, Krzysztof Mrózek, Selen Yilmaz, Jessica Kohlschmidt, Karilyn T. Larkin, James S. Blachly, Christopher C. Oakes, Jill Buss, Christopher J. Walker, Shelley Orwick, Vindi Jurinovic, Maja Rothenberg-Thurley, Annika Maria Dufour, Stephanie Schneider, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard Josef Woermann, Wolfgang Hiddemann, Jan Braess, Marion Subklewe, Karsten Spiekermann, Andrew J. Carroll, William G. Blum, Bayard L. Powell, Jonathan E. Kolitz, Joseph O. Moore, Robert James Mayer, Richard M. Stone, Geoffrey L. Uy, Wendy Stock, Klaus H. Metzeler, H. Leighton Grimes, John C. Byrd, Nathan Salomonis, Tobias Herold, Alice S. Mims, Ann-Kathrin Eisfeld
Publikováno v:
Blood. 140:936-939
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12caeb6a0bdcbd10a46442c664324422
https://doi.org/10.1182/blood-2022-165395
https://doi.org/10.1182/blood-2022-165395