Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christopher J Unterberger"'
Autor:
Christopher J. Unterberger, Sean J. McIlwain, Philippos K. Tsourkas, Vilena I. Maklakova, Jordyn L. Prince, Abigail Onesti, Rong Hu, John J. Kopchick, Steven M. Swanson, Paul C. Marker
Publikováno v:
The Prostate. 83:416-429
Humans with inactivating mutations in growth hormone receptor (GHR) have lower rates of cancer, including prostate cancer. Similarly, mice with inactivating Ghr mutations are protected from prostatic intraepithelial neoplasia in the C3(1)/TAg prostat
Autor:
Lauren Repp, Christopher J. Unterberger, Zhengqing Ye, John B. Feltenberger, Steven M. Swanson, Paul C. Marker, Glen S. Kwon
Publikováno v:
Nanomaterials, Vol 11, Iss 10, p 2745 (2021)
Docetaxel (DTX) is among the most frequently prescribed chemotherapy drugs and has recently been shown to extend survival in advanced prostate cancer patients. However, the poor water solubility of DTX prevents full exploitation of this potent antica
Externí odkaz:
https://doaj.org/article/1aee56640a144de084baf3208fc1ab00
Publikováno v:
Endocr Relat Cancer
Interest in investigating the role of the growth hormone/insulin-like growth factor 1 axis in the initiation and progression of experimentally induced carcinomas has arisen due to several observations in the human population. First, subjects with Lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e91f98e55a4242dfa6bd5239fec16f
https://europepmc.org/articles/PMC10140676/
https://europepmc.org/articles/PMC10140676/
Autor:
Christopher J Unterberger, Stephanie M McGregor, John J Kopchick, Steven M Swanson, Paul C Marker
Publikováno v:
Endocrinology
Female SV40 C3(1) T-antigen (C3(1)/TAg) transgenic mice develop mammary tumors that are molecularly similar to human basal-like breast cancers with 100% incidence at 16 weeks of age. To determine the requirement for growth hormone (GH) signaling in t
Autor:
Christopher J Unterberger, Vilena I Maklakova, Michelle Lazar, Paige D Arneson, Sean J Mcilwain, Philippos K Tsourkas, Rong Hu, John J Kopchick, Steven M Swanson, Paul C Marker
Publikováno v:
Endocrinology
Previous studies investigating the effects of blocking the growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis in prostate cancer found no effects of the growth hormone receptor (GHR) antagonist, pegvisomant, on the growth of grafted human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d86b0828272ed7c6f96a6269ca68c0f
https://europepmc.org/articles/PMC8995093/
https://europepmc.org/articles/PMC8995093/
Autor:
Chad M. Vezina, Richard B. Halberg, Steven R Oakes, Brett Mueller, Paul C. Marker, Hannah Ruetten, Christopher J Unterberger, Anne E. Turco, Nicholas M Girardi, Steven M. Swanson, Enrique J Avila, Kyle A Wegner
Publikováno v:
J Pathol
We genetically engineered expression of an activated form of P110 alpha, the catalytic subunit of PI3K, in mouse prostate epithelium to create a mouse model of direct PI3K activation (Pbsn-cre4Prb;PI3KGOF/+ ). We hypothesized that direct activation w
Autor:
Christopher J Unterberger, Steven M. Swanson, Paul C. Marker, Zhengqing Ye, John B. Feltenberger, Glen S. Kwon, Lauren Repp
Publikováno v:
Nanomaterials, Vol 11, Iss 2745, p 2745 (2021)
Nanomaterials
Volume 11
Issue 10
Nanomaterials
Volume 11
Issue 10
Docetaxel (DTX) is among the most frequently prescribed chemotherapy drugs and has recently been shown to extend survival in advanced prostate cancer patients. However, the poor water solubility of DTX prevents full exploitation of this potent antica
Autor:
Colin Longhurst, Paul C. Marker, Michelle Lazar, Paige D Arneson, Christopher J Unterberger, Daniel D. Lantvit, Steven M. Swanson
Publikováno v:
Endocrinology
Previously, we reported that N-methyl-N-nitrosourea (MNU)-induced mammary tumors could be established in mutant spontaneous dwarf rats (SDRs), which lack endogenous growth hormone (GH) by supplementing with exogenous GH, and almost all such tumors re