Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christopher J Roome"'
Autor:
Christopher J Roome, Bernd Kuhn
Publikováno v:
eLife, Vol 9 (2020)
Dendritic coincidence detection is fundamental to neuronal processing yet remains largely unexplored in awake animals. Specifically, the underlying dendritic voltage–calcium relationship has not been directly addressed. Here, using simultaneous vol
Externí odkaz:
https://doaj.org/article/1d67edfe72d84889bcfaac9adf0b574d
Autor:
Christopher J. Roome, Bernd Kuhn
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Dendritic integration is important for information processing in the brain. Here, in awake mice, authors combine simultaneous dendritic recording of voltage and calcium signals, with somatic recording from Purkinje neurons, enabling characterization
Externí odkaz:
https://doaj.org/article/608e8bd18ab54c2794a663ba98de7e12
Autor:
Bernd Kuhn, Christopher J. Roome
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
ANNINE-6 and ANNINE-6plus are voltage-sensitive dyes that when combined with two-photon microscopy are ideal for recording of neuronal voltages in vivo, in both bulk loaded tissue and the dendrites of single neurons. Here, we describe in detail but f
Externí odkaz:
https://doaj.org/article/eba552a0081a4492b2524decd13b6adf
Autor:
Haroon eAnwar, Christopher J. Roome, Hermina eNedelescu, Weiliang eChen, Bernd eKuhn, Erik eDe Schutter
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
There is growing interest in understanding calcium dynamics in dendrites, both experimentally and computationally. Many processes influence these dynamics, but in dendrites there is a strong contribution of morphology because the peak calcium levels
Externí odkaz:
https://doaj.org/article/eaabd525ecd348899f72e79a22a853e8
Autor:
Christopher J. Roome, Ruth M. Empson
Publikováno v:
Neuroscience Letters. 663:25-28
Expression of the fast calcium extrusion protein, PMCA2, in the cerebellum is amongst the highest found throughout the central nervous system, and unsurprisingly PMCA2 knockout mice exhibit cerebellar ataxia or loss of controlled movement. The sole o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947ee8c9415f25e4d1662b7cb2b2b20f
https://doi.org/10.1016/j.neulet.2017.09.045
https://doi.org/10.1016/j.neulet.2017.09.045
Autor:
Christopher J. Roome, Bernd Kuhn
Publikováno v:
Neuroscience research. 152
Voltage imaging is the next generation of functional imaging in neuroscience. It promises to resolve neuronal activity 10 to 100-times faster than calcium imaging and to report not only supra but also subthreshold activity on a single cell or even su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0899ada1e41be2fbf350466714d010c
https://pubmed.ncbi.nlm.nih.gov/31758973
https://pubmed.ncbi.nlm.nih.gov/31758973
Autor:
Christopher J. Roome, Bernd Kuhn
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
ANNINE-6 and ANNINE-6plus are voltage-sensitive dyes that when combined with two-photon microscopy are ideal for recording of neuronal voltages in vivo, in both bulk loaded tissue and the dendrites of single neurons. Here, we describe in detail but f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0742d5e9fd7d34673669c0754ef26a85
https://doi.org/10.3389/fncel.2019.00321
https://doi.org/10.3389/fncel.2019.00321
Autor:
Bernd Kuhn, Christopher J. Roome
Publikováno v:
Neuromethods ISBN: 9781493997015
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::633891cf52f35545a105e9edd8167ecc
https://doi.org/10.1007/978-1-4939-9702-2_13
https://doi.org/10.1007/978-1-4939-9702-2_13
Autor:
David Thinnes, Bernd Kuhn, Jonas F. Vibell, Christopher J. Roome, Philipp Flotho, Daniel J. Strauss
Publikováno v:
Journal of Neuroscience Methods. 353:109076
BackgroundIn the context of signal analysis and pattern matching, alignment of 1D signals for the comparison of signal morphologies is an important problem. For image processing and computer vision, 2D optical flow (OF) methods find wide application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aaee63ff0bbe66a11fea6711bdea8be
http://id.nii.ac.jp/1394/00001812/
http://id.nii.ac.jp/1394/00001812/