Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Christopher J H Jones"'
Autor:
Svati H Shah, Neil J Freedman, Lisheng Zhang, David R Crosslin, David H Stone, Carol Haynes, Jessica Johnson, Sarah Nelson, Liyong Wang, Jessica J Connelly, Michael Muehlbauer, Geoffrey S Ginsburg, David C Crossman, Christopher J H Jones, Jeffery Vance, Michael H Sketch, Christopher B Granger, Christopher B Newgard, Simon G Gregory, Pascal J Goldschmidt-Clermont, William E Kraus, Elizabeth R Hauser
Publikováno v:
PLoS Genetics, Vol 5, Iss 1, p e1000318 (2009)
Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease (CAD). We have previously identified genetic linkage to familial CAD in the genomic region of NPY. We performed follow-up genetic, biostatistical, and functional analysis of
Externí odkaz:
https://doaj.org/article/088af6cb44d4434485213c7d62fcc9d7
Autor:
Jessica J Connelly, Tianyuan Wang, Julie E Cox, Carol Haynes, Liyong Wang, Svati H Shah, David R Crosslin, A Brent Hale, Sarah Nelson, David C Crossman, Christopher B Granger, Jonathan L Haines, Christopher J H Jones, Jeffery M Vance, Pascal J Goldschmidt-Clermont, William E Kraus, Elizabeth R Hauser, Simon G Gregory
Publikováno v:
PLoS Genetics, Vol 2, Iss 8, p e139 (2006)
The transcription factor GATA2 plays an essential role in the establishment and maintenance of adult hematopoiesis. It is expressed in hematopoietic stem cells, as well as the cells that make up the aortic vasculature, namely aortic endothelial cells
Externí odkaz:
https://doaj.org/article/4ab45e6f573e4eb1b06d0f30bd8e2483
Autor:
Stuart McPherson, Richard Gilson, Eleanor Barnes, Fleur Hudson, David Smith, Graham S Cooke, Aftab Ala, Chinlye Ch'ng, Leanne McCabe, Daniel M. Forton, Ben Stone, Martin Wiselka, Stephen T. Barclay, Sarah Pett, Emily Dennis, Mark Nelson, Stephen D. Ryder, Sanjay Bhagani, Christopher J. H. Jones, M. Azim Ansari, Dung Nguyen, Jane Collier, Sumita Verma, Rachel Halford, Ann Sarah Walker
Publikováno v:
Wellcome Open Research
BackgroundThe WHO has identified the need for a better understanding of which patients can be cured with ultrashort course hepatitis C (HCV) therapyMethods202 individuals with chronic HCV were randomised to fixed-duration shortened therapy (8 weeks)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2784175db2751eef96befb8a8a62ebc7
https://doi.org/10.12688/wellcomeopenres.16594.1
https://doi.org/10.12688/wellcomeopenres.16594.1
Autor:
Ania Korszun, Andrew J.M. Broadley, Michael P. Frenneaux, Christopher J. H. Jones, Valentina Moskvina
Publikováno v:
Psychosomatic Medicine. 67:648-651
OBJECTIVES: Depression is independently associated with increased cardiovascular morbidity and mortality, including sudden cardiac death, and this risk is observed even in patients who have been successfully treated for depression. Recent studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00a2b0a750511c9aff31116951ddb96
https://doi.org/10.1097/01.psy.0000170829.91643.24
https://doi.org/10.1097/01.psy.0000170829.91643.24
Autor:
Christopher B. Granger, Silke Schmidt, Bernhard R. Winkelmann, Christopher J. H. Jones, Vincent Mooser, Margaret A. Pericak-Vance, Jonathan L. Haines, William K. Scott, Elizabeth R. Hauser, David C. Crossman, Allen D. Roses, William E. Kraus
Publikováno v:
American Heart Journal. 145:602-613
Background Coronary artery disease (CAD) is the leading cause of death and a leading cause of disability in the developed world. Early onset (premature) coronary artery disease (EOCAD) is known to have a particularly strong genetic component. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4063a84bbd2f9a27b5964483bf0cb1d6
https://doi.org/10.1067/mhj.2003.13
https://doi.org/10.1067/mhj.2003.13
Publikováno v:
Cardiovascular Research. 29:585-596
The technology is available for the study of the coronary microcirculation in vivo and in vitro. Coronary microvascular resistance depends continually upon intrinsic and extrinsic regulatory influences operating on different vascular microdomains. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4258727ffa404feb07eaa05d16425d06
https://doi.org/10.1016/s0008-6363(96)88626-3
https://doi.org/10.1016/s0008-6363(96)88626-3
Publikováno v:
Circulation. 91:1807-1813
Background The purpose of this study was to test the hypothesis that endothelium-derived nitric oxide (NO) participates in coronary microvascular responses to adenosine and pacing-induced increases in metabolic demand by maintaining an optimal distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d43903544554e334261ec21b8f458fc
https://doi.org/10.1161/01.cir.91.6.1807
https://doi.org/10.1161/01.cir.91.6.1807
Autor:
Colin G. Caro, Fumihiko Kajiya, Toichi Takenaka, M. John Lever, Katsuhiko Tsujioka, Yasuo Ogasawara, Osamu Hiramatsu, Christopher J. H. Jones, Kim H. Parker
Publikováno v:
Cardiovascular Research. 28:1686-1693
Objective: The aim was to study the effects of altered heart rate and vasoactive drugs on the blood velocity patterns in the region of an arterial bifurcation. Methods: Blood velocity profiles were measured in an exposed iliofemoral bifurcation of pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1796c2ae5fd2b509d5207d3be95723b3
https://doi.org/10.1093/cvr/28.11.1686
https://doi.org/10.1093/cvr/28.11.1686
Publikováno v:
Basic Research in Cardiology. 88:2-10
We have recently gained evidence that segmental coronary microvascular diameters, and therefore resistances, are controlled by myogenic and endothelial responses to pressure and flow. Furthermore, intact heart studies are demonstrating that these mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9aff4866fd2e8f711132ec9661c04e5
https://doi.org/10.1007/bf00788525
https://doi.org/10.1007/bf00788525
Autor:
Colin G. Caro, Christopher J. H. Jones, Graham A. MacGregor, Donald R. J. Singer, Nicholas V. Watkins
Publikováno v:
Clinical Science. 78:431-435
1. We compared the velocity waveforms in the superficial femoral artery measured by multichannel Doppler ultrasound in 45 subjects: 21 patients with untreated essential hypertension and 24 normal subjects of similar age and sex. 2. The pattern of art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b397b9e7f0b8bb64df6e31956248d8
https://doi.org/10.1042/cs0780431
https://doi.org/10.1042/cs0780431