Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Christopher J Fields"'
Autor:
Christopher J Fields, Lu Li, Nicholas M Hiers, Tianqi Li, Peike Sheng, Taha Huda, Jixiu Shan, Lauren Gay, Tongjun Gu, Jiang Bian, Michael S Kilberg, Rolf Renne, Mingyi Xie
Publikováno v:
PLoS Genetics, Vol 17, Iss 12, p e1009934 (2021)
MicroRNAs (miRNA) are short non-coding RNAs widely implicated in gene regulation. Most metazoan miRNAs utilize the RNase III enzymes Drosha and Dicer for biogenesis. One notable exception is the RNA polymerase II transcription start sites (TSS) miRNA
Externí odkaz:
https://doaj.org/article/9e16ab6be9ab4e51a070766391d0856e
Autor:
Verena Ras, Gerrit Botha, Shaun Aron, Katie Lennard, Imane Allali, Shantelle Claassen-Weitz, Kilaza Samson Mwaikono, Dane Kennedy, Jessica R Holmes, Gloria Rendon, Sumir Panji, Christopher J Fields, Nicola Mulder
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008640 (2021)
With more microbiome studies being conducted by African-based research groups, there is an increasing demand for knowledge and skills in the design and analysis of microbiome studies and data. However, high-quality bioinformatics courses are often im
Externí odkaz:
https://doaj.org/article/9bacf3fec9e341ab96d9da36cfaa71d4
Autor:
David P Tchouassi, Ephantus J Muturi, Samwel O Arum, Chang-Hyun Kim, Christopher J Fields, Baldwyn Torto
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 6, p e0007361 (2019)
The composition and structure of microbial communities associated with mosquitoes remain poorly understood despite their important role in host biology and potential to be harnessed as novel strategies for mosquito-borne disease control. We employed
Externí odkaz:
https://doaj.org/article/12c839a43eac4042a39a6f5fef8f01c3
Autor:
C Victor Jongeneel, Ovokeraye Achinike-Oduaran, Ezekiel Adebiyi, Marion Adebiyi, Seun Adeyemi, Bola Akanle, Shaun Aron, Efejiro Ashano, Hocine Bendou, Gerrit Botha, Emile Chimusa, Ananyo Choudhury, Ravikiran Donthu, Jenny Drnevich, Oluwadamila Falola, Christopher J Fields, Scott Hazelhurst, Liesl Hendry, Itunuoluwa Isewon, Radhika S Khetani, Judit Kumuthini, Magambo Phillip Kimuda, Lerato Magosi, Liudmila Sergeevna Mainzer, Suresh Maslamoney, Mamana Mbiyavanga, Ayton Meintjes, Danny Mugutso, Phelelani Mpangase, Richard Munthali, Victoria Nembaware, Andrew Ndhlovu, Trust Odia, Adaobi Okafor, Olaleye Oladipo, Sumir Panji, Venesa Pillay, Gloria Rendon, Dhriti Sengupta, Nicola Mulder
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 6, p e1005419 (2017)
The H3ABioNet pan-African bioinformatics network, which is funded to support the Human Heredity and Health in Africa (H3Africa) program, has developed node-assessment exercises to gauge the ability of its participating research and service groups to
Externí odkaz:
https://doaj.org/article/1cbda16871d74b1aa7fa0221beb1cb98
Autor:
Giovanni Lugli, Aaron M Cohen, David A Bennett, Raj C Shah, Christopher J Fields, Alvaro G Hernandez, Neil R Smalheiser
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139233 (2015)
To assess the value of exosomal miRNAs as biomarkers for Alzheimer disease (AD), the expression of microRNAs was measured in a plasma fraction enriched in exosomes by differential centrifugation, using Illumina deep sequencing. Samples from 35 person
Externí odkaz:
https://doaj.org/article/99b56f8863ec452fb69923c7a2b36c11
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Aggression is influenced by individual variation in temperament as well as behavioral plasticity in response to adversity. DNA methylation is stably maintained over time, but also reversible in response to specific environmental c
Externí odkaz:
https://doaj.org/article/24ecaf912d894fd697b60b0167fa241e
Autor:
Deepika Arora, Alvaro G. Hernandez, Kimberly K. O. Walden, Christopher J. Fields, Guiping Yan
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7311
Root-lesion nematodes (genus Pratylenchus) belong to a diverse group of plant-parasitic nematodes (PPN) with a worldwide distribution. Despite being an economically important PPN group of more than 100 species, genome information related to Pratylenc
Autor:
Rina Fujiwara, Si-Nan Zhai, Dongming Liang, Matthew Tracey, Xu-Kai Ma, Aayushi P. Shah, Christopher J. Fields, María Saraí Mendoza-Figueroa, Michele C. Meline, Deirdre C. Tatomer, Li Yang, Jeremy E. Wilusz
The metazoan-specific Integrator complex catalyzes 3’ end processing of small nuclear RNAs (snRNAs) as well as premature transcription termination events that attenuate expression of many protein-coding genes. Integrator has RNA endonuclease and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aee3aa3fd838b1fed64fea52b7dbe6c0
https://doi.org/10.1101/2023.03.05.531184
https://doi.org/10.1101/2023.03.05.531184
Autor:
Ruian Ke, Pamela P. Martinez, Rebecca L. Smith, Laura L. Gibson, Agha Mirza, Madison Conte, Nicholas Gallagher, Chun Huai Luo, Junko Jarrett, Ruifeng Zhou, Abigail Conte, Tongyu Liu, Mireille Farjo, Kimberly K. O. Walden, Gloria Rendon, Christopher J. Fields, Leyi Wang, Richard Fredrickson, Darci C. Edmonson, Melinda E. Baughman, Karen K. Chiu, Hannah Choi, Kevin R. Scardina, Shannon Bradley, Stacy L. Gloss, Crystal Reinhart, Jagadeesh Yedetore, Jessica Quicksall, Alyssa N. Owens, John Broach, Bruce Barton, Peter Lazar, William J. Heetderks, Matthew L. Robinson, Heba H. Mostafa, Yukari C. Manabe, Andrew Pekosz, David D. McManus, Christopher B. Brooke
Publikováno v:
Nature Microbiology. 7:640-652
Autor:
Lu Li, Casey M. Guardia, Peike Sheng, Jonathan D. Licht, Tianqi Li, Yuzhi Wang, Mingyi Xie, Nicholas M. Hiers, Christopher J. Fields, Jianping Li
Publikováno v:
Genes & Development. 35:1595-1609
Binding of microRNAs (miRNAs) to mRNAs normally results in post-transcriptional repression of gene expression. However, extensive base-pairing between miRNAs and target RNAs can trigger miRNA degradation, a phenomenon called target RNA-directed miRNA