Screening a large pediatric cohort with GH deficiency for mutations in genes regulating pituitary development and GH secretion: Frequencies, phenotypes and growth outcomesResearch in context

Autor: Werner F. Blum, Jürgen Klammt, Serge Amselem, Heike M. Pfäffle, Marie Legendre, Marie-Laure Sobrier, Marie-Pierre Luton, Christopher J. Child, Christine Jones, Alan G. Zimmermann, Charmian A. Quigley, Gordon B. Cutler, Jr, Cheri L. Deal, Jan Lebl, Ron G. Rosenfeld, John S. Parks, Roland W. Pfäffle

Publikováno v: EBioMedicine, Vol 36, Iss , Pp 390-400 (2018)

Background: Pituitary development and GH secretion are orchestrated by multiple genes including GH1, GHRHR, GLI2, HESX1, LHX3, LHX4, PROP1, POU1F1, and SOX3. We aimed to assess their mutation frequency and clinical relevance in children with severe G

Externí odkaz: https://doaj.org/article/eb38d45a2af84fb1a420e9f01ae4ca4c

Conversations and Reactions Around Severe Hypoglycemia (CRASH) Study: Results From People With Diabetes and Caregivers in the United States

Autor: Frank J. Snoek, Erik Spaepen, Barbara A. Nambu, Christopher J. Child, Sanjay Bajpai, Zaneta Balantac, Donald M. Bushnell, Robin Pokrzywinski, Beth D. Mitchell

Publikováno v: Snoek, F J, Spaepen, E, Nambu, B A, Child, C J, Bajpai, S, Balantac, Z, Bushnell, D M, Pokrzywinski, R & Mitchell, B D 2022, ' Conversations and Reactions Around Severe Hypoglycemia (CRASH) Study : Results From People With Diabetes and Caregivers in the United States ', Clinical Diabetes, vol. 40, no. 4, pp. 477-488 . https://doi.org/10.2337/cd21-0131
Clinical Diabetes, 40(4), 477-488. American Diabetes Association Inc.

A survey was conducted in eight countries to examine conversations around, and experiences and treatments during, severe hypoglycemia among people with diabetes and caregivers of people with diabetes. This article reports a subgroup analysis from the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8586f48042714c68096d23d8a7fe1eb
https://doi.org/10.2337/figshare.19653537

Nasal Glucagon was Efficacious in Reversing Insulin-Induced Hypoglycemia Across a Range of Nadir Blood Glucose Levels

Autor: Jean-Francois Yale, Rebecca Threlkeld, Qianqian Wang, Parag Garhyan, Douglas James, Christopher J Child, Yu Yan, Andreas Holstein

Publikováno v: Hand in Hand zum Ziel – einfach.besser.messbar www.diabeteskongress.de.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a52b3d37b04c8d4a32645ed1a6d6f6d0
https://doi.org/10.1055/s-0042-1746300

Author response for 'Previously unrecognised risk factors for severe hypoglycaemia requiring emergency medical care in insulin‐treated type 2 diabetes: results from a real‐world nested case‐control study'

Autor: null Julie Settles, null Hong Kan, null Christopher J. Child, null Magdaliz Gorritz, null Jasjit K. Multani, null Catherine B. McGuiness, null Rolin L. Wade, null Brian M. Frier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525b9cef09888dd4d2d53456bd794e75
https://doi.org/10.1111/dom.14690/v3/response1

348-P: Nasal Glucagon Was Efficacious in Reversing Insulin-Induced Hypoglycemia across a Range of Nadir Blood Glucose Levels

Autor: Yu Yan, Christopher J. Child, Parag Garhyan, Douglas James, Jean-François Yale, Qianqian Wang, Rebecca J. Threlkeld

Publikováno v: Diabetes. 70

Background: Nasal glucagon (NG) is a ready-to-use rescue treatment for severe hypoglycemia. We evaluated efficacy and safety of NG in reversing insulin-induced hypoglycemia for a range of nadir blood glucose (BG) levels in adults with T1D or T2D. Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04252bffa58ade7c76ac287b1ee87b03
https://doi.org/10.2337/db21-348-p