Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Christopher J Bowman"'
Autor:
Karin C Lilja, Nan Zhang, Alessandro Magli, Volkan Gunduz, Christopher J Bowman, Robert W Arpke, Radbod Darabi, Michael Kyba, Rita Perlingeiro, Brian D Dynlacht
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176190 (2017)
Pluripotent stem cells (PSC) hold great promise for the treatment of human skeletal muscle diseases. However, it remains challenging to convert PSC to skeletal muscle cells, and the mechanisms by which the master regulatory transcription factor, Pax7
Externí odkaz:
https://doaj.org/article/ff5142d41f5a41b9be3f6295abfd4b22
Autor:
Zeynep A Oztug Durer, Jeffrey A Cohlberg, Phong Dinh, Shelby Padua, Krista Ehrenclou, Sean Downes, James K Tan, Yoko Nakano, Christopher J Bowman, Jessica L Hoskins, Chuhee Kwon, Andrew Z Mason, Jorge A Rodriguez, Peter A Doucette, Bryan F Shaw, Joan Selverstone Valentine
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e5004 (2009)
Mutations in the gene encoding Cu-Zn superoxide dismutase (SOD1) are one of the causes of familial amyotrophic lateral sclerosis (FALS). Fibrillar inclusions containing SOD1 and SOD1 inclusions that bind the amyloid-specific dye thioflavin S have bee
Externí odkaz:
https://doaj.org/article/7c43d9021ab5409cac773e59444305b8
Autor:
Natasha R Catlin, Christopher J Bowman, Sarah N Campion, Elise M Lewis, William S Nowland, Christine Stethem, Gregg D Cappon
Publikováno v:
Toxicological Sciences. 189:225-236
Ervogastat (PF-06865571) is a small molecule diacylglycerol acyltransferase 2 (DGAT2) inhibitor being developed for the oral treatment of nonalcoholic steatohepatitis (NASH) with liver fibrosis. DGAT2 is a key enzyme in triglyceride synthesis in tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8406685f49264eb55b560fab52e2d7d6
https://doi.org/10.1093/toxsci/kfac077
https://doi.org/10.1093/toxsci/kfac077
Autor:
Bernard S. Buetow, Gregg D Cappon, Laura M. Aschenbrenner, Lawrence Updyke, Vince R. Torti, Mark Evans, Shana R. Dalton, Steven Bailey, Christopher J. Bowman
Publikováno v:
International Journal of Toxicology. 41:389-401
Bococizumab is an anti-PCSK9 monoclonal antibody that was intended for the treatment of hypercholesterolemia. After reviewing the 6-month rat toxicity study data, in which there was a low spontaneous tumor incidence, unrelated to bococizumab administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7d16867d57951ce3092b8f8d26e92f
https://doi.org/10.1177/10915818221106397
https://doi.org/10.1177/10915818221106397
Autor:
Christopher J, Bowman, Fabiola, Medeiros, Oluwole, Fadare, Ankur R, Sangoi, Andrew E, Horvai, W Patrick, Devine, W Glenn, McCluggage, Joseph T, Rabban
Publikováno v:
International Journal of Gynecological Pathology. 42:1-10
Gynecologic tract origin of inflammatory myofibroblastic tumor (IMT), a receptor tyrosine kinase fusion driven tumor with malignant potential, is uncommon and mostly involves the uterine corpus where misclassification as a smooth muscle tumor may occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa081c3cb550f3a6089a3dc543cc8ff1
https://doi.org/10.1097/pgp.0000000000000858
https://doi.org/10.1097/pgp.0000000000000858
Autor:
Annaliesa S. Anderson, William S. Nowland, Natasha R. Catlin, Gregg D. Cappon, Scott Engel, Ingrid L. Scully, Christopher J. Bowman, Cynthia M. Rohde, Sandra M. Buitrago
Publikováno v:
Birth Defects Research. 113:1343-1356
A maternal Group B Streptococcus (GBS) six-valent polysaccharide conjugate vaccine (GBS6) is being developed to protect neonates and infants up to 3 months of age through passive transfer of antibodies from the mother to the infant. Fertility and dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88aff61b35ca63e2d5d7ed89a832d473
https://doi.org/10.1002/bdr2.1953
https://doi.org/10.1002/bdr2.1953
Autor:
Sarah N. Campion, Christopher J. Bowman, Antje Fuchs, David Karanian, Payal Rana, Gregg D. Cappon
Publikováno v:
Birth defects researchREFERENCES.
Achondroplasia is an autosomal disorder caused by point mutation in the gene encoding fibroblast growth factor receptor 3 (FGFR3) and resulting in gain of function. Recifercept is a potential disease modifying treatment for achondroplasia and functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3261062f97b1f60d4f7ae6a010cfedae
https://pubmed.ncbi.nlm.nih.gov/36367445
https://pubmed.ncbi.nlm.nih.gov/36367445
Autor:
William S. Nowland, Steven W. Kumpf, Trenton T. Ross, Christopher J. Bowman, Gregg D. Cappon, Donald S Stedman, Scott D Davenport, William P. Esler, Christine Stethem, Natasha R. Catlin, Elise M. Lewis, Sarah N. Campion
Publikováno v:
Toxicological Sciences. 179:183-194
Acetyl-CoA carboxylase (ACC) is an enzyme within the de novo lipogenesis (DNL) pathway and plays a role in regulating lipid metabolism. Pharmacologic ACC inhibition has been an area of interest for multiple potential indications including oncology, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6d9eb6a77626c055c46264ceba500b
https://doi.org/10.1093/toxsci/kfaa169
https://doi.org/10.1093/toxsci/kfaa169
Autor:
Rick Adler, Famke Aeffner, Laura E. Armstrong, Dmitri Artemov, Adam D. Aulbach, Bindu M. Bennet, Eric A. Blomme, Brad Bolon, Christopher J. Bowman, Molly Boyle, Alys Bradley, Dino Bradley, Danielle Brown, Pierre R. Bushel, Ellen Cannady, Mark F. Cesta, Curtis Chan, Jennifer A. Chilton, Peter J.M. Clements, Torrie A. Crabbs, Myrtle A. Davis, Sandy Eldridge, Daniela Ennulat, Jeffrey Everitt, Isabel Figueroa, James D. Fikes, Thomas Forest, Catherine A. Foss, John R. Foster, Kathleen Gabrielson, Shayne C. Gad, Kapil Gadkar, Jinping Gan, David Garcia-Tapia, Frank J. Geoly, Wendy G. Halpern, Jerry F. Hardisty, Wanda M. Haschek, Kathleen Marie Heinz-Taheny, Kristi Helke, Lauren E. Himmel, Mark J. Hoenerhoff, Jennifer L. Ingram–Ross, Armando R. Irizarry Rovira, Evan B. Janovitz, Kishore Katyayan, Charlotte M. Keenan, Angela King-Herbert, Steven T. Laing, Lois D. Lehman-McKeeman, Na Li, Calvert Louden, Claire Lyons, Kevin McDorman, Elizabeth McInnes, Lyn Miller Wancket, Sheroy Minocherhomji, Sébastien Monette, James Morrison, Vasanthi Mowat, Sydney Mukaratirwa, Keith Nelson, Arun R. Pandiri, Tracey Papenfuss, Nita Patel, Daniel J. Patrick, Shari A. Price, Deepa B. Rao, James T. Raymond, Jennifer Rojko, Colin G. Rousseaux, Sara F. Santagostino, Aaron Sargeant, Christina Satterwhite, A. Eric Schultze, Vanessa Schumacher, Cheryl Scudamore, Keith R. Shockley, Bhanu P. Singh, David M. Stresser, Polina Sysa-Shah, Debra A. Tokarz, Terry Van Vleet, Matthew A. Wallig, Jin Wang, Cynthia J. Willson, Kristin Lewis Wilson, Christopher T. Winkelmann, Jeffrey C. Wolf, Charles Wood, Daniela Bumbaca Yadav, Mark Zarella
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3831ed61c4599a4d47034bfb7e19d99
https://doi.org/10.1016/b978-0-12-821044-4.01002-5
https://doi.org/10.1016/b978-0-12-821044-4.01002-5
