Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christopher J, Viggiani"'
Autor:
Simon R.V. Knott, Oscar M. Aparicio, Simon Tavaré, Jared M. Peace, Alexandra E. Rex, A. Zachary Ostrow, Christopher J. Viggiani, Yan Gan
Publikováno v:
Cell. 148(1-2):99-111
SummaryThe replication of eukaryotic chromosomes is organized temporally and spatially within the nucleus through epigenetic regulation of replication origin function. The characteristic initiation timing of specific origins is thought to reflect the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ec0fcf73a820591439f014ebf754b3
Publikováno v:
Cold Spring Harb Perspect Biol
Science policy offers a challenging and rewarding career path for scientists interested in the social, ethical, and legal implications of their field. This topic encompasses a broad spectrum of activities all in support of advancing the scientific en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac310f85e25585fe540ce626061463d
https://doi.org/10.1101/cshperspect.a032854
https://doi.org/10.1101/cshperspect.a032854
Publikováno v:
Genes & Development. 23:1077-1090
In higher eukaryotes, heritable gene silencing is associated with histone deacetylation and late replication timing. In Saccharomyces cerevisiae, the histone deacetylase Rpd3 regulates gene expression and also modulates replication timing; however, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e304534044738adccb99838960760ac1
https://doi.org/10.1101/gad.1784309
https://doi.org/10.1101/gad.1784309
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1300
Chromatin immunoprecipitation (ChIP) is a widely used method to study interactions between proteins and discrete chromosomal loci in vivo. ChIP was originally developed for in vivo analysis of protein associations with candidate DNA sequences known o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::682e8cdd1788019ca1893d98c486fb3b
https://pubmed.ncbi.nlm.nih.gov/25916712
https://pubmed.ncbi.nlm.nih.gov/25916712
Publikováno v:
Yeast. 23:1045-1051
The thymidine analogue BrdU is a powerful tool for analysing nucleotide incorporation in studies of DNA replication or repair. S. cerevisiae lacks the thymidine salvage pathway that enables efficient cellular uptake and incorporation of thymidine ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4a382364e040003568198a6b5b1326
https://doi.org/10.1002/yea.1406
https://doi.org/10.1002/yea.1406
Publikováno v:
Molecular and Cellular Biology. 24:4769-4780
The replication of eukaryotic genomes follows a temporally staged program, in which late origin firing often occurs within domains of altered chromatin structure(s) and silenced genes. Histone deacetylation functions in gene silencing in some late-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6485d151f799596ef8f509ace51264
https://doi.org/10.1128/mcb.24.11.4769-4780.2004
https://doi.org/10.1128/mcb.24.11.4769-4780.2004
Publikováno v:
Cold Spring Harbor protocols. 2010(2)
INTRODUCTIONThe incorporation of thymidine analogs, such as 5-bromo-2′-deoxyuridine (BrdU), into newly synthesized DNA is a powerful tool for analysis of DNA replication, repair, and other aspects of DNA metabolism. In Saccharomyces cerevisiae, sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d63dd85cbcf985f8c7e961742be6859
https://pubmed.ncbi.nlm.nih.gov/20150148
https://pubmed.ncbi.nlm.nih.gov/20150148
Publikováno v:
Epigenetics. 4(6)
Duplication of the eukaryotic genome occurs in the context of a chromatin template that is actively engaged in regulating gene expression and other protein-DNA interactions. Chromatin structures influence the dynamics of DNA replication by regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a4c47e98015e16b6176482b641e233
https://pubmed.ncbi.nlm.nih.gov/19736523
https://pubmed.ncbi.nlm.nih.gov/19736523
Publikováno v:
BMC Bioinformatics, Vol 10, Iss 1, p 305 (2009)
BMC Bioinformatics
BMC Bioinformatics
Background Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been employed to examine features such as protein binding and histone modifications on a genome-wide scale in a variety of cell types. Array data from the latter studies typica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb9c57bd36cf49982627f00879b11ae
http://www.biomedcentral.com/1471-2105/10/305
http://www.biomedcentral.com/1471-2105/10/305
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 521
Chromatin immunoprecipitation (ChIP) is a widely used method to study the interactions between proteins and discrete chromosomal loci in vivo. Originally, ChIP was developed for analysis of protein associations with DNA sequences known or suspected t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09da7b1b6cb44dfca2d85a722aaa4ea1
https://pubmed.ncbi.nlm.nih.gov/19563111
https://pubmed.ncbi.nlm.nih.gov/19563111