Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Christopher J, Vavricka"'
Autor:
Musashi Takenaka, Kouhei Kamasaka, Kim Daryong, Keiko Tsuchikane, Seiha Miyazawa, Saeko Fujihana, Yoshimi Hori, Christopher J. Vavricka, Akira Hosoyama, Hiroko Kawasaki, Tomokazu Shirai, Michihiro Araki, Akira Nakagawa, Hiromichi Minami, Akihiko Kondo, Tomohisa Hasunuma
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Computational mining of useful enzymes and biosynthesis pathways is a powerful strategy for metabolic engineering. Through systematic exploration of all conceivable combinations of enzyme reactions, including both known compounds
Externí odkaz:
https://doaj.org/article/eec63415caf84260b34d1edf12f160e1
Autor:
Daimei Miura, Wakana Hayashi, Kensuke Hirano, Ikkei Sasaki, Kaori Tsukakoshi, Hidehumi Kakizoe, Satomi Asai, Christopher J. Vavricka, Hitoshi Takemae, Tetsuya Mizutani, Wakako Tsugawa, Koji Sode, Kazunori Ikebukuro, Ryutaro Asano
Publikováno v:
Advanced Science, Vol 11, Iss 43, Pp n/a-n/a (2024)
Abstract The SARS‐CoV‐2 pandemic has challenged more scientists to detect viruses and to visualize virus‐containing spots for diagnosis and infection control; however, detection principles of commercially available technologies are not optimal
Externí odkaz:
https://doaj.org/article/20db616a976b4cc3afbd9d28c7e29901
Autor:
Christopher J. Vavricka, Shunsuke Takahashi, Naoki Watanabe, Musashi Takenaka, Mami Matsuda, Takanobu Yoshida, Ryo Suzuki, Hiromasa Kiyota, Jianyong Li, Hiromichi Minami, Jun Ishii, Kenji Tsuge, Michihiro Araki, Akihiko Kondo, Tomohisa Hasunuma
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Producing plant secondary metabolites by microbes is limited by the known enzymatic reactions. Here, the authors apply machine learning to predict missing link enzymes of benzylisoquinoline alkaloid (BIA) biosynthesis in Papaver somniferum, and valid
Externí odkaz:
https://doaj.org/article/baf664b334934b1d89704e14d973d831
Autor:
Yuichi Kato, Tomoki Oyama, Kentaro Inokuma, Christopher J. Vavricka, Mami Matsuda, Ryota Hidese, Katsuya Satoh, Yutaka Oono, Jo-Shu Chang, Tomohisa Hasunuma, Akihiko Kondo
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Kato et al. describe the isolation of a mutant Chlamydomonas sp. KOR1 that accumulates lipid even during diurnal cycles and has extensive mutations in the ISA1 gene encoding a starch debranching enzyme (DBE). They further demonstrate that disruption
Externí odkaz:
https://doaj.org/article/4db72b85cc5148b19e7f91423b27bf31
Autor:
Christopher J. Vavricka, Takanobu Yoshida, Yuki Kuriya, Shunsuke Takahashi, Teppei Ogawa, Fumie Ono, Kazuko Agari, Hiromasa Kiyota, Jianyong Li, Jun Ishii, Kenji Tsuge, Hiromichi Minami, Michihiro Araki, Tomohisa Hasunuma, Akihiko Kondo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Bioproduction of tetrahydropapaveroline (THP) is limited by the specificity of monoamine oxidase (MAO). Here, the authors identify an insect 3,4-dihydroxyphenylacetaldehyde synthase (DHPAAS) that can bypass MAO for direct aldehyde production and demo
Externí odkaz:
https://doaj.org/article/cff5bceaa4c341b49a36d8f2870f8cb6
Autor:
Yuichi Kato, Yusuke Fujihara, Christopher J. Vavricka, Jo-Shu Chang, Tomohisa Hasunuma, Akihiko Kondo
Publikováno v:
Biotechnology for Biofuels, Vol 12, Iss 1, Pp 1-11 (2019)
Abstract Background Light/dark cycling is an inevitable outdoor culture condition for microalgal biofuel production; however, the influence of this cycling on cellular lipid production has not been clearly established. The general aim of this study w
Externí odkaz:
https://doaj.org/article/69bea4bbcdc941eab1a29c667f35b952
Autor:
Varada Jagadeesh, Takanobu Yoshida, Misugi Uraji, Nobuyuki Okahashi, Fumio Matsuda, Christopher J. Vavricka, Kenji Tsuge, Akihiko Kondo
Publikováno v:
ACS Synthetic Biology. 12:305-318
Recombination of biosynthetic gene clusters including those of non-ribosomal peptide synthetases (NRPSs) is essential for understanding the mechanisms of biosynthesis. Due to relatively huge gene cluster sizes ranging from 10 to 150 kb, the prevalenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77a3cd4cf1869940df528e016fdff0e
https://doi.org/10.1021/acssynbio.2c00565
https://doi.org/10.1021/acssynbio.2c00565
Autor:
Christopher J. Vavricka, Chiaki Muto, Tomohisa Hasunuma, Yoshinobu Kimura, Michihiro Araki, Yan Wu, George F. Gao, Hiroshi Ohrui, Minoru Izumi, Hiromasa Kiyota
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract The design, synthesis and application of N-acetylneuraminic acid-derived compounds bearing anomeric sulfo functional groups are described. These novel compounds, which we refer to as sulfo-sialic acid analogues, include 2-decarboxy-2-deoxy-2
Externí odkaz:
https://doaj.org/article/d71999dbcf09495f926bec89b3dbfc54
Autor:
Shunki Katayama, Mitsuki Nishimoto, Tatsuya Ura, Taiki Ishimoto, Kousuke Ida, Yuki Sato, Christopher J. Vavricka, Minoru Izumi, Hiromasa Kiyota
Maoecrystal V is a highly oxidized and rearranged norterpenoid isolated from the Chinese herb, Isodon eriocalyx. A synthetic route for the C/D/E-ring core compound of maoecrystal V has been developed. Introduction of the C1 fragment to the D/E-ring c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e6b77a7bfc477638983e2a2836ddb90
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2556
Depending on the strain, influenza A virus causes animal, zoonotic, pandemic, or seasonal influenza with varying degrees of severity. Two surface glycoprotein spikes, hemagglutinin (HA) and neuraminidase (NA), are the most important influenza A virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c5b016874f16b83d7cc046bd3fc1a86
https://pubmed.ncbi.nlm.nih.gov/36175642
https://pubmed.ncbi.nlm.nih.gov/36175642