Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Christopher J, Apolito"'
Autor:
Thomas G. Consler, Kenneth H. Pearce, Chris J. Delves, Thomas B. Stanley, John T. Moore, Randy K. Bledsoe, Millard H. Lambert, Eugene L. Stewart, Valerie G. Montana, Derek J. Parks, David D. McKee, Christopher J. Apolito, H. Eric Xu, Timothy M. Willson
Publikováno v:
Cell. 110:93-105
Transcriptional regulation by the glucocorticoid receptor (GR) is mediated by hormone binding, receptor dimerization, and coactivator recruitment. Here, we report the crystal structure of the human GR ligand binding domain (LBD) bound to dexamethason
Autor:
James F. Truax, J. Patrick Condreay, Jennings F. Worley, Christopher J. Apolito, T. A. Kost, Gang An, Jeffrey L. Pfohl
Publikováno v:
Receptors and Channels. 8:99-111
A variety of transfection approaches have been used to deliver plasmids encoding ion channel genes into cells. We have used the baculovirus transduction system, BacMam, to demonstrate transient expression of multi-subunit KATP channels in CHO-K1 and
Autor:
Randy K. Bledsoe, Timothy M. Willson, Ryan P. Trump, Jason A. Holt, Eugene L. Stewart, Kevin P. Madauss, Thomas B. Stanley, Millard H. Lambert, Shawn P. Williams, Kenneth H. Pearce, Christopher J. Apolito
Publikováno v:
The Journal of biological chemistry. 280(35)
Ligand binding is the first step in hormone regulation of mineralocorticoid receptor (MR) activity. Here, we report multiple crystal structures of MR (NR3C2) bound to both agonist and antagonists. These structures combined with mutagenesis studies re
Autor:
Jeffrey L, Pfohl, Jennings F, Worley, J Patrick, Condreay, Gang, An, Christopher J, Apolito, Tom A, Kost, James F, Truax
Publikováno v:
Receptorschannels. 8(2)
A variety of transfection approaches have been used to deliver plasmids encoding ion channel genes into cells. We have used the baculovirus transduction system, BacMam, to demonstrate transient expression of multi-subunit KATP channels in CHO-K1 and