Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christopher Isely"'
Autor:
Michael A. Hendley, Christopher Isely, Kendall P. Murphy, Hayley E. Hall, Prakasam Annamalai, R. Michael Gower
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Ectopic lipid accumulation, the deposition of lipids in lean tissue, is linked to type 2 diabetes through an association with insulin resistance. It occurs when adipose tissue fails to meet lipid storage needs and there is lipid spillover into tissue
Externí odkaz:
https://doaj.org/article/370d08cae0dd4b179556b771273b4479
Autor:
Hayley E. Hall, Kendall P. Murphy, Griffin J. Carter, Alexandra T. Patterson, R. Michael Gower, Michael A. Hendley, Christopher Isely
Publikováno v:
J Biomed Mater Res A
Lipid overload of the adipose tissue, which can be caused by overnutrition, underlies metabolic disease. We hypothesized that increasing the energy demand of adipose tissue is a promising strategy to combat excessive lipid accumulation. Resveratrol,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5142d115ce19694e78d5d4c4e63ca6
https://europepmc.org/articles/PMC7855839/
https://europepmc.org/articles/PMC7855839/
Publikováno v:
J Drug Deliv Sci Technol
For the past several decades, drug-encapsulated polymer particles have been investigated as locally-delivered, long-acting therapies. The most common method of producing such particles is the oil in water solvent extraction technique. Using this tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8fda27923f9fc116053cee211b7971
https://doi.org/10.1016/j.jddst.2021.102672
https://doi.org/10.1016/j.jddst.2021.102672
Autor:
Prakasam Annamalai, Safaa Kader, Kendall P. Murphy, R. Michael Gower, Christopher Isely, Esmaiel Jabbari, Michael A. Hendley
Publikováno v:
Int J Pharm
Resveratrol is a small molecule produced by various plants with a remarkable range of beneficial functions in animals. One of these is stimulating signaling pathways in adipose tissue that protect against obesity. Unfortunately, resveratrol suffers f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb46a35289d928719c77f35fa11a2a0f
https://pubmed.ncbi.nlm.nih.gov/31265884
https://pubmed.ncbi.nlm.nih.gov/31265884
Publikováno v:
Int J Pharm
Particles for biomedical applications can be produced by emulsifying biocompatible polymers dissolved in an organic solvent in water. The emulsion is then transferred to an extraction bath that removes the solvent from the dispersed droplets, which l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f0724d27df44c38437be64930d85b7
https://doi.org/10.1016/j.ijpharm.2020.119917
https://doi.org/10.1016/j.ijpharm.2020.119917
Autor:
Kendall P. Murphy, Michael A. Hendley, Edsel Peña, Prakasam Annamalai, R. Michael Gower, Christopher Isely
Publikováno v:
ACS applied materialsinterfaces. 10(50)
As biomaterial therapies emerge to address adipose tissue dysfunction that underlies metabolic disease, the immune response to these systems must be established. As a potential therapy, we are investigating resveratrol delivery from porous poly(lacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db6a8550737575f8ca925423fd38f4b
https://pubmed.ncbi.nlm.nih.gov/30462474
https://pubmed.ncbi.nlm.nih.gov/30462474
Autor:
Heather L. Struckman, Christopher Isely, Kendall P. Murphy, R. Michael Gower, Michael A. Hendley, Prakasam Annamalai
Publikováno v:
Biomaterials
Underlying metabolic disease is poor adipose tissue function characterized by impaired glucose tolerance and low expression of health promoting adipokines. Currently, no treatments specifically target the adipose tissue and we are investigating polym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a332a26153021a1cb3bbd2caa9c9123e
https://doi.org/10.1016/j.biomaterials.2019.119281
https://doi.org/10.1016/j.biomaterials.2019.119281