Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christopher Icke"'
Autor:
Jessica Gray, Von Vergel L Torres, Emily Goodall, Samantha A McKeand, Danielle Scales, Christy Collins, Laura Wetherall, Zheng Jie Lian, Jack A Bryant, Matthew T Milner, Karl A Dunne, Christopher Icke, Jessica L Rooke, Thamarai Schneiders, Peter A Lund, Adam F Cunningham, Jeff A Cole, Ian R Henderson
Publikováno v:
eLife, Vol 12 (2024)
Klebsiella pneumoniae is a global public health concern due to the rising myriad of hypervirulent and multidrug-resistant clones both alarmingly associated with high mortality. The molecular mechanisms underpinning these recalcitrant K. pneumoniae in
Externí odkaz:
https://doaj.org/article/cf25e48630df47d7b08338ad3b7a5d15
Autor:
Irene Beriotto, Christopher Icke, Yanina R. Sevastsyanovich, Amanda E. Rossiter, Giacomo Romagnoli, Silvana Savino, Freya J. Hodges, Jeffrey A. Cole, Allan Saul, Calman A. MacLennan, Adam F. Cunningham, Francesca Micoli, Ian R. Henderson
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The autotransporter protein secretion system has been used previously to target the secretion of heterologous proteins to the bacterial cell surface and the extracellular milieu at the laboratory scale. The platform is of particular interest
Externí odkaz:
https://doaj.org/article/60ed576cf7734e6eb03dbfcc34413bd6
Autor:
Emily C A Goodall, Georgia L Isom, Jessica L Rooke, Karthik Pullela, Christopher Icke, Zihao Yang, Gabriela Boelter, Alun Jones, Isabel Warner, Rochelle Da Costa, Bing Zhang, James Rae, Wee Boon Tan, Matthias Winkle, Antoine Delhaye, Eva Heinz, Jean-Francois Collet, Adam F Cunningham, Mark A Blaskovich, Robert G Parton, Jeff A Cole, Manuel Banzhaf, Shu-Sin Chng, Waldemar Vollmer, Jack A Bryant, Ian R Henderson
Publikováno v:
PLoS Genetics, Vol 17, Iss 12, p e1009586 (2021)
The cell envelope is essential for viability in all domains of life. It retains enzymes and substrates within a confined space while providing a protective barrier to the external environment. Destabilising the envelope of bacterial pathogens is a co
Externí odkaz:
https://doaj.org/article/ec2a22d24ae74fa89c1da995d1848199
Autor:
Jessica L. Rooke, Christopher Icke, Timothy J. Wells, Amanda E. Rossiter, Douglas F. Browning, Faye C. Morris, Jack C. Leo, Monika S. Schütz, Ingo B. Autenrieth, Adam F. Cunningham, Dirk Linke, Ian R. Henderson
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The BAM complex in Escherichia coli is composed of five proteins, BamA-E. BamA and BamD are essential for cell viability and are required for the assembly of β-barrel outer membrane proteins. Consequently, BamA and BamD are indispensable for secreti
Externí odkaz:
https://doaj.org/article/fd9ef170f5574032b9cbbacb3621a6cb
Autor:
Christopher Icke, Freya J Hodges, Karthik Pullela, Samantha A McKeand, Jack Alfred Bryant, Adam F Cunningham, Jeff A Cole, Ian R Henderson
Publikováno v:
eLife, Vol 10 (2021)
Protein acylation is critical for many cellular functions across all domains of life. In bacteria, lipoproteins have important roles in virulence and are targets for the development of antimicrobials and vaccines. Bacterial lipoproteins are secreted
Externí odkaz:
https://doaj.org/article/b09b42d7284d412aa5219c5349c608ba
Autor:
Jack Alfred Bryant, Faye C Morris, Timothy J Knowles, Riyaz Maderbocus, Eva Heinz, Gabriela Boelter, Dema Alodaini, Adam Colyer, Peter J Wotherspoon, Kara A Staunton, Mark Jeeves, Douglas F Browning, Yanina R Sevastsyanovich, Timothy J Wells, Amanda E Rossiter, Vassiliy N Bavro, Pooja Sridhar, Douglas G Ward, Zhi-Soon Chong, Emily CA Goodall, Christopher Icke, Alvin CK Teo, Shu-Sin Chng, David I Roper, Trevor Lithgow, Adam F Cunningham, Manuel Banzhaf, Michael Overduin, Ian R Henderson
Publikováno v:
eLife, Vol 9 (2020)
The Gram-negative outer-membrane envelops the bacterium and functions as a permeability barrier against antibiotics, detergents, and environmental stresses. Some virulence factors serve to maintain the integrity of the outer membrane, including DolP
Externí odkaz:
https://doaj.org/article/f638738df7ef4c79a9be99c12141984c
Autor:
Freya J. Hodges, Von Vergel L. Torres, Adam F. Cunningham, Ian R. Henderson, Christopher Icke
Publikováno v:
Advances in Microbial Physiology ISBN: 9780443193347
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d6bd571c6495f338dc9f8ff5d50a33f
https://doi.org/10.1016/bs.ampbs.2022.10.003
https://doi.org/10.1016/bs.ampbs.2022.10.003
Autor:
Emily C. A. Goodall, Faye C. Morris, Samantha A. McKeand, Rudi Sullivan, Isabel A. Warner, Emma Sheehan, Gabriela Boelter, Christopher Icke, Adam F. Cunningham, Jeffrey A. Cole, Manuel Banzhaf, Jack A. Bryant, Ian R. Henderson
In recent years the availability of genome sequence information has grown logarithmically resulting in the identification of a plethora of uncharacterised genes. To address this gap in functional annotation, many high-throughput screens have been dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de11d6a040243e09fc2c73604b9b0334
https://doi.org/10.1101/2022.02.16.479736
https://doi.org/10.1101/2022.02.16.479736
Autor:
Ian Henderson, Irene Beriotto, Christopher Icke, Yanina Sevastsyanovich, Amanda Rossiter, Giacomo Romagnoli, Silvana Savino, Jeffrey Cole, Allan Saul, Calman MacLennan, Adam Cunningham, Francesca Micoli
Background: The autotransporter protein secretion system has previously been used to target the secretion of heterologous proteins to the bacterial cell surface and the extracellular milieu at laboratory scale. The platform is of particular interest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9641edcfa4d18ee2630aaba01e2460af
https://doi.org/10.21203/rs.3.rs-1300960/v1
https://doi.org/10.21203/rs.3.rs-1300960/v1
Autor:
Shu-Sin Chng, James Rae, Jean-François Collet, Karthik Pullela, Eva Heinz, Bing Zhang, Georgia L. Isom, Emily C. A. Goodall, Matthias Winkle, Mark A. T. Blaskovich, Jessica L. Rooke, Waldemar Vollmer, Ian R. Henderson, Wee Boon Tan, Christopher Icke, Antoine Delhaye, Adam F. Cunningham, Jeffrey A. Cole, Jack A. Bryant, Robert G. Parton
The cell envelope is essential for viability in all kingdoms of life. It retains enzymes and substrates within a confined space while providing a protective barrier to the external environment. Destabilising the envelope of bacterial pathogens is a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c1f8cd32d6adfb5dcd7d716fea11e89
https://doi.org/10.1101/2021.04.16.440158
https://doi.org/10.1101/2021.04.16.440158