Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Christopher I. Murray"'
S‐Nitrosoglutathione Reductase Deficiency Causes Aberrant Placental S‐Nitrosylation and Preeclampsia
Autor:
Shathiyah Kulandavelu, Raul A. Dulce, Christopher I. Murray, Michael A. Bellio, Julia Fritsch, Rosemeire Kanashiro‐Takeuchi, Himanshu Arora, Ellena Paulino, Daniel Soetkamp, Wayne Balkan, Jenny E. Van Eyk, Joshua M. Hare
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 5 (2022)
Background Preeclampsia, a leading cause of maternal and fetal mortality and morbidity, is characterized by an increase in S‐nitrosylated proteins and reactive oxygen species, suggesting a pathophysiologic role for dysregulation in nitrosylation an
Externí odkaz:
https://doaj.org/article/7c58d4a5e22d48efa2ccc96e5a6e59bc
Autor:
Allen A. Champagne, Nicole S. Coverdale, Andrew Ross, Yining Chen, Christopher I. Murray, David Dubowitz, Douglas J. Cook
Publikováno v:
NeuroImage: Clinical, Vol 26, Iss , Pp - (2020)
Blood oxygenation level dependent (BOLD) resting-state functional magnetic resonance imaging (rs-fMRI) may serve as a sensitive marker to identify possible changes in the architecture of large-scale networks following mild traumatic brain injury (mTB
Externí odkaz:
https://doaj.org/article/9bb7951a377447d0a088dca9c57fe9b0
Publikováno v:
Mass spectrometry reviewsREFERENCES.
Sample preparation for mass spectrometry-based proteomics has many tedious and time-consuming steps that can introduce analytical errors. In particular, the steps around the proteolytic digestion of protein samples are prone to inconsistency. One rou
Publikováno v:
Proceedings of the National Academy of Sciences. 116:7879-7888
The I Ks current has an established role in cardiac action potential repolarization, and provides a repolarization reserve at times of stress. The underlying channels are formed from tetramers of KCNQ1 along with one to four KCNE1 accessory subunits,
Autor:
Jennifer E. Van Eyk, Justyna-Fert Bober, Blandine Chazarin Orgel, Conor Phebus, Alejandro Rivas, Kirstin E Washington, Angela Mc Ardle, Danica-Mae Manalo, James Go, Susan Cheng, Casey W Coutelin Johnson, Vidya Venkatraman, Christopher I. Murray, Stephen R. Pennington, Qin Fu, Koen Raedschelders, Annie Moradian, Aleksandra Binek
Publikováno v:
Clinical chemistry. 68(3)
Background Accurate discovery assay workflows are critical for identifying authentic circulating protein biomarkers in diverse blood matrices. Maximizing the commonalities in the proteomic workflows between different biofluids simplifies the approach
Autor:
Isabelle Vallee, Andrew Ross, Allen A. Champagne, Nicole S. Coverdale, Christopher I. Murray, Douglas J. Cook
Publikováno v:
Brain injury. 35(7)
Soldiers are exposed to significant repetitive head trauma, which may disrupt functional and structural brain connectivity patterns.Integrate resting-state functional MRI (rs-fMRI) and diffusion tensor imaging (DTI) to characterize changes in connect
S-nitrosoglutathione reductase deficiency causes aberrant placental S-nitrosylation and preeclampsia
Autor:
Christopher I. Murray, Ellena C. Paulino, Joshua M. Hare, Raul A Dulce, Shathiyah Kulandavelu, Rosemeire M. Kanashiro-Takeuchi, Julia Fritsch, Michael A. Bellio, Jennifer E. Van Eyk, Wayne Balkan, Himanshu Arora, Daniel Soetkamp
Preeclampsia (PE), a leading cause of maternal and fetal mortality and morbidity, is characterized by an increase in S-nitrosylated (SNO) proteins and reactive oxygen species (ROS), suggesting a pathophysiologic role for dysregulation in nitrosylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6c512152ea338b264ead55ba4000d19
https://doi.org/10.1101/2020.07.01.183012
https://doi.org/10.1101/2020.07.01.183012
Autor:
Andrew Ross, Allen A. Champagne, Yining Chen, Nicole S. Coverdale, Christopher I. Murray, David J. Dubowitz, Douglas J. Cook
Publikováno v:
NeuroImage : Clinical
NeuroImage: Clinical, Vol 26, Iss, Pp-(2020)
NeuroImage: Clinical, Vol 26, Iss, Pp-(2020)
Highlights 1 BOLD functional connectivity may be confounded by local cerebrovascular physiology. 2 Changes in baseline perfusion and functional connectivity were documented post-mTBI. 3 Normalization of functional connectivity by local physiology nar
Publikováno v:
Biophysical Journal. 113:415-425
The slow delayed rectifier potassium current (IKs) is a key repolarizing current during the cardiac action potential. It consists of four KCNQ1 α-subunits and up to four KCNE1 β-subunits, which are thought to reside within external clefts of the ch
Publikováno v:
Biophysical Journal. 118:332a