Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christopher I van de Wetering"'
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1911 (2008)
The effect of Bcl-2 on oncogenesis is complex and expression may either delay or accelerate oncogenesis. The pro-oncogenic activity is attributed to its well characterized anti-apoptotic function while the anti-oncogenic function has been attributed
Externí odkaz:
https://doaj.org/article/d623c4cfdfc74675b056ff74c7f61729
Autor:
Mitchell C. Coleman, Douglas R. Spitz, C. Michael Knudson, Brian J. Smith, Christopher I. van de Wetering
Publikováno v:
Free Radical Biology and Medicine. 44:1677-1686
Increased reactive oxygen species (ROS) such as superoxide have been implicated as causal elements of oncogenesis. A variety of cancers have displayed changes in steady state levels of key antioxidant enzymes with the mitochondrial form of superoxide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10ad8dddc1243c852b5984efbb52638
https://doi.org/10.1016/j.freeradbiomed.2008.01.022
https://doi.org/10.1016/j.freeradbiomed.2008.01.022
Publikováno v:
Cancer Research. 67:8081-8088
A hallmark of carcinogenesis is resistance to cell death. However, recent studies indicate that Bax expression increased apoptosis and promoted oncogenesis. In this study, we hypothesized that Bax promotes tumor formation by increasing chromosomal in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2ce2a068bee9b1ef03afdb040df5ef
https://doi.org/10.1158/0008-5472.can-07-1666
https://doi.org/10.1158/0008-5472.can-07-1666
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1911 (2008)
PLoS ONE
PLoS ONE
The effect of Bcl-2 on oncogenesis is complex and expression may either delay or accelerate oncogenesis. The pro-oncogenic activity is attributed to its well characterized anti-apoptotic function while the anti-oncogenic function has been attributed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b202571a36485035caedae7639bfe7
http://europepmc.org/articles/PMC2270898?pdf=render
http://europepmc.org/articles/PMC2270898?pdf=render
Publikováno v:
Experimental neurology. 178(1)
We have discovered novel transport properties of cholera toxin subunit b beyond well-known anterograde and retrograde axonal transport. Injection of 1500 microg of CTb intraperitoneally or intravenously in young adult mice resulted in generalized enh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343ea35578a858f8843f631cd39e3ba7
https://pubmed.ncbi.nlm.nih.gov/12460616
https://pubmed.ncbi.nlm.nih.gov/12460616