Zobrazeno 1 - 10
of 19 471
pro vyhledávání: '"Christopher I"'
Autor:
Marion Denos, Yi-Qian Sun, Ben Michael Brumpton, Yafang Li, Demetrius Albanes, Andrea Burnett-Hartman, Peter T. Campbell, Sébastien Küry, Christopher I. Li, Emily White, Jewel N. Samadder, Mark A. Jenkins, Xiao-Mei Mai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The roles of sex hormones such as estradiol, testosterone, and sex hormone-binding globulin (SHBG) in the etiology of lung and colorectal cancers in women, among the most common cancers after breast cancer, are unclear. This Mendelian random
Externí odkaz:
https://doaj.org/article/c84f598213d5405c8f1524e9194ae165
Autor:
Chenyang Li, Thinh T. Nguyen, Jian-Rong Li, Xingzhi Song, Junya Fujimoto, Latasha Little, Curtis Gumb, Chi-Wan B. Chow, Ignacio I. Wistuba, Andrew P. Futreal, Jianhua Zhang, Shawna M. Hubert, John V. Heymach, Jia Wu, Christopher I. Amos, Jianjun Zhang, Chao Cheng
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-14 (2024)
Abstract Lung Cancer remains the leading cause of cancer deaths in the USA and worldwide. Non-small cell lung cancer (NSCLC) harbors high transcriptomic intratumor heterogeneity (RNA-ITH) that limits the reproducibility of expression-based prognostic
Externí odkaz:
https://doaj.org/article/b6fe0a65261748579d8ae587987a1d01
Autor:
Bryan R. Gorman, Sun-Gou Ji, Michael Francis, Anoop K. Sendamarai, Yunling Shi, Poornima Devineni, Uma Saxena, Elizabeth Partan, Andrea K. DeVito, Jinyoung Byun, Younghun Han, Xiangjun Xiao, Don D. Sin, Wim Timens, Jennifer Moser, Sumitra Muralidhar, Rachel Ramoni, Rayjean J. Hung, James D. McKay, Yohan Bossé, Ryan Sun, Christopher I. Amos, VA Million Veteran Program, Saiju Pyarajan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Lung cancer remains the leading cause of cancer mortality, despite declining smoking rates. Previous lung cancer GWAS have identified numerous loci, but separating the genetic risks of lung cancer and smoking behavioral susceptibility remain
Externí odkaz:
https://doaj.org/article/dac86f32ac504f5bbdb7376d6931934e
Autor:
Christopher I. Higginson, Morgan K. Bifano, Kelly M. Seymour, Rachel L. Orr, Kurt M. DeGoede, Jill S. Higginson
Publikováno v:
NeuroSci, Vol 5, Iss 3, Pp 328-338 (2024)
Evidence supporting a link between gait and cognition is accumulating. However, the relation between executive functioning and spatiotemporal gait parameters has received little attention. This is surprising since these gait variables are related to
Externí odkaz:
https://doaj.org/article/e6d24beaca03486b9bf29f322678826b
Autor:
Erping Long, Jinhu Yin, Ju Hye Shin, Yuyan Li, Bolun Li, Alexander Kane, Harsh Patel, Xinti Sun, Cong Wang, Thong Luong, Jun Xia, Younghun Han, Jinyoung Byun, Tongwu Zhang, Wei Zhao, Maria Teresa Landi, Nathaniel Rothman, Qing Lan, Yoon Soo Chang, Fulong Yu, Christopher I. Amos, Jianxin Shi, Jin Gu Lee, Eun Young Kim, Jiyeon Choi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Genome-wide association studies (GWAS) identified over fifty loci associated with lung cancer risk. However, underlying mechanisms and target genes are largely unknown, as most risk-associated variants might regulate gene expression in a con
Externí odkaz:
https://doaj.org/article/c8946b388f1b4930819dd2bcbe00021c
Publikováno v:
Geochemical Transactions, Vol 25, Iss 1, Pp 1-25 (2024)
Abstract Quarrying of rock aggregates generates produced water that, if not handled properly will be a source of pollution for nearby water bodies, thus affecting the chemistry of the water. This study examined the chemistry, impact of quarrying acti
Externí odkaz:
https://doaj.org/article/daae36510a98460099798c0afdf9c493
Autor:
Jian-Rong Li, Vikram Shaw, Yupei Lin, Xiang Wang, Muhammad Aminu, Yong Li, Jia Wu, Jianjun Zhang, Christopher I. Amos, Chao Cheng
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-8 (2024)
Abstract The spatial arrangement of immune cells within the tumor microenvironment (TME) and their interactions play critical roles in the initiation and development of cancer. Several advanced technologies such as imaging mass cytometry (IMC) provid
Externí odkaz:
https://doaj.org/article/aaf281e60e4647fcbb0b84d76b7e4671
Autor:
Steffi Oesterreich, Leigh Pate, Adrian V. Lee, Fangyuan Chen, Rachel C. Jankowitz, Rita Mukhtar, Otto Metzger, Matthew J. Sikora, Christopher I. Li, Christos Sotiriou, Osama S. Shah, Thijs Koorman, Gary Ulaner, Jorge S. Reis-Filho, Nancy M. Davidson, Karen Van Baelen, Laurie Hutcheson, Siobhan Freeney, Flora Migyanka, Claire Turner, Patrick Derksen, Todd Bear, Christine Desmedt
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract There is growing awareness of the unique etiology, biology, and clinical presentation of invasive lobular breast cancer (ILC), but additional research is needed to ensure translation of findings into management and treatment guidelines. We c
Externí odkaz:
https://doaj.org/article/674206de519c4c9a91765a34839d5098
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Single nucleotide substitutions are the most common type of somatic mutations in cancer genome. The goal of this study was to use publicly available somatic mutation data to quantify negative and positive selection in individual lung tumors
Externí odkaz:
https://doaj.org/article/57b57ec9dc0a412192c68504bf423a8d
Autor:
John S. A. Mattick, Robin E. Bromley, Kaylee J. Watson, Ricky S. Adkins, Christopher I. Holt, Jarrett F. Lebov, Benjamin C. Sparklin, Tyonna S. Tyson, David A. Rasko, Julie C. Dunning Hotopp
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT RNA transcripts are potential therapeutic targets, yet bacterial transcripts have uncharacterized biodiversity. We developed an algorithm for transcript prediction called tp.py using it to predict transcripts (mRNA and other RNAs) in Escheri
Externí odkaz:
https://doaj.org/article/d0edc818c52849dfb46e0614f9812657