Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Christopher Hino"'
Autor:
Won Jin Jeon, Bowon Joung, Jin Hyun Moon, Christopher Hino, Daniel Park, Bryan Pham, Dan Ran Castillo, Esther Chong, Simmer Kaur, Chanell Grismore, Huynh Cao
Publikováno v:
Hematology, Vol 28, Iss 1 (2023)
ABSTRACTObjectives Sickle cell disease (SCD) is characterized by a mutation in the beta-globin gene resulting in abnormal hemoglobin S (HgbS). The significant sequela of SCD include anemia and recurrent vaso-occlusive episodes (VOEs) which may effect
Externí odkaz:
https://doaj.org/article/f12fdf9da1114be0a2702a7d6eb4ca41
Publikováno v:
Current Problems in Cancer: Case Reports, Vol 10, Iss , Pp 100232- (2023)
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have demonstrated remarkable efficacy for use in advanced non-small-cell lung cancer (NSCLC). However, the inevitable acquisition of resistance mutations to targeted TKI therapy
Externí odkaz:
https://doaj.org/article/51dd34c037844ff593c6b5773af21b15
Autor:
Yi Xu, Christopher Hino, David J. Baylink, Jeffrey Xiao, Mark E. Reeves, Jiang F. Zhong, Saied Mirshahidi, Huynh Cao
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-5 (2022)
Abstract Acute myeloid leukemia (AML) has the lowest survival rate among the leukemias. Targeting intracellular metabolism and energy production in leukemic cells can be a promising therapeutic strategy for AML. Recently, we presented the successful
Externí odkaz:
https://doaj.org/article/f736b737ff18458391da2cc5d0a70964
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Understanding the factors which shape T-lymphocyte immunity is critical for the development and application of future immunotherapeutic strategies in treating hematological malignancies. The thymus, a specialized central lymphoid organ, plays importa
Externí odkaz:
https://doaj.org/article/3fe6b2fa0454464c816cdc5d965407f6
Autor:
Christopher Hino, Bryan Pham, Austin L. Gray, Jun Wang, Dan Ran Castillo, Mojtaba Akhtari, Yan Liu
Publikováno v:
Pathology and Oncology Research, Vol 28 (2022)
Mantle cell lymphoma (MCL) is a rare and aggressive non-Hodgkin’s B cell lymphoma characterized by the translocation t(11;14) (q13;32) and overexpression of CCND1. MCL is immunophenotypically identified as CD20+, CD5+, CyclinD1+, CD43+, CD10−, BC
Externí odkaz:
https://doaj.org/article/302fae764143420e95b6b01fdaab8cef
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The prognosis of sarcomatoid renal cell carcinoma has changed dramatically with the emergence of immune checkpoint inhibitors. Notably the use of nivolumab and ipilimumab combination therapy has demonstrated promising durable therapeutic response for
Externí odkaz:
https://doaj.org/article/d4ea5b149a52474c8480821047e9bc48
Autor:
Yi Xu, Christopher Hino, David J. Baylink, Jeffrey Xiao, Mark E. Reeves, Jiang F. Zhong, Saied Mirshahidi, Huynh Cao
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/cc0b5534a8bc40e2bb227d73dd9360dc
Autor:
Christopher Hino, Bryan Pham, Daniel Park, Chieh Yang, Michael H.K. Nguyen, Simmer Kaur, Mark E. Reeves, Yi Xu, Kevin Nishino, Lu Pu, Sue Min Kwon, Jiang F. Zhong, Ke K. Zhang, Linglin Xie, Esther G. Chong, Chien-Shing Chen, Vinh Nguyen, Dan Ran Castillo, Huynh Cao
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1410 (2022)
The tumor microenvironment (TME) plays an essential role in the development, proliferation, and survival of leukemic blasts in acute myeloid leukemia (AML). Within the bone marrow and peripheral blood, various phenotypically and functionally altered
Externí odkaz:
https://doaj.org/article/7689272f960f44b0be05cc1d06cf9ad9
Autor:
Huynh Cao, Verena Tadros, Benjamin Hiramoto, Kevin Leeper, Christopher Hino, Jeffrey Xiao, Bryan Pham, Do Hyun Kim, Mark E. Reeves, Chien-Shing Chen, Jiang F. Zhong, Ke K. Zhang, Linglin Xie, Samiksha Wasnik, David J. Baylink, Yi Xu
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1038 (2022)
Disease relapse is a common cause of treatment failure in FMS-like tyrosine kinase 3 (FLT3) mutated acute myeloid leukemia (AML). In this study, to identify therapeutic targets responsible for the survival and proliferation of leukemic cells (blasts)
Externí odkaz:
https://doaj.org/article/a2d89bcac6e7403c81113892bef62085
Autor:
Emily He, Christopher Hino, Osaigbokan Aihie, Anthonia Ijeli, Amaka C Ugoh, Anum Akhlaq, Olive C Osuoji, John Eboma, Joan Ezomo, Precious Onobraigho, Precious O Eseaton, Ehizogie Edigin
Publikováno v:
Cureus.