Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Christopher H. Eskiw"'
Publikováno v:
Lifestyle Genomics (2022)
Background: Our daily intake of food provides nutrients for the maintenance of health, growth and development. The field of nutrigenomics aims to link dietary intake/nutrients to changes in epigenetic status and gene expression. Summary: Although the
Externí odkaz:
https://doaj.org/article/b5bba58dd15d4f2cb2c95f4cab433829
Autor:
Ishita S. Mehta, Kumars Riyahi, Rita Torres Pereira, Karen J. Meaburn, Martin Figgitt, Ian R. Kill, Christopher H. Eskiw, Joanna M. Bridger
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
This study demonstrates, and confirms, that chromosome territory positioning is altered in primary senescent human dermal fibroblasts (HDFs). The chromosome territory positioning pattern is very similar to that found in HDFs made quiescent either by
Externí odkaz:
https://doaj.org/article/05d60265ec75408abded1657357ca06f
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-8 (2018)
Abstract Objectives Hi-C is a proximity-based ligation reaction used to detect regions of the genome that are close in 3D space (or “interacting”). Typically, results from Hi-C experiments (contact maps) are visualized as heatmaps or Circos plots
Externí odkaz:
https://doaj.org/article/2c7a886f8f68480da07136aaf22ba860
Autor:
Ata Ghavidel, Kunal Baxi, Martin Prusinkiewicz, Cynthia Swan, Zach R. Belak, Christopher H. Eskiw, Carlos E. Carvalho, Troy A. Harkness
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 5, Pp 1579-1592 (2018)
The yeast, Saccharomyces cerevisiae, like other higher eukaryotes, undergo a finite number of cell divisions before exiting the cell cycle due to the effects of aging. Here, we show that yeast aging begins with the nuclear exclusion of Hcm1 in young
Externí odkaz:
https://doaj.org/article/5102f45718a241e8b263a725b4e00d9f
Autor:
Lily R. Zehfus, Zoe E. Gillespie, Carla Almendáriz-Palacios, Nicholas H. Low, Christopher H. Eskiw
Publikováno v:
Cells, Vol 10, Iss 10, p 2643 (2021)
It is generally accepted that dietary phenolics from fruits are of significant importance to human health. Unfortunately, there is minimal published data on how differences in phenolic structure(s) impact biological pathways at cellular and molecular
Externí odkaz:
https://doaj.org/article/aefb394ed4d04a41aa7c79a4acf8a99c
Autor:
Carla Almendáriz-Palacios, Zoe E. Gillespie, Matthew Janzen, Valeria Martinez, Joanna M. Bridger, Troy A. A. Harkness, Darrell D. Mousseau, Christopher H. Eskiw
Publikováno v:
Biomedicines, Vol 8, Iss 7, p 188 (2020)
Cellular health is reliant on proteostasis—the maintenance of protein levels regulated through multiple pathways modulating protein synthesis, degradation and clearance. Loss of proteostasis results in serious disease and is associated with aging.
Externí odkaz:
https://doaj.org/article/dabe5c2be942465da22e52566196e34a
Autor:
Brett Trost, Catherine A. Moir, Zoe E. Gillespie, Anthony Kusalik, Jennifer A. Mitchell, Christopher H. Eskiw
Publikováno v:
Royal Society Open Science, Vol 2, Iss 9 (2015)
DNA microarrays and RNA sequencing (RNA-seq) are major technologies for performing high-throughput analysis of transcript abundance. Recently, concerns have been raised regarding the concordance of data derived from the two techniques. Using cDNA lib
Externí odkaz:
https://doaj.org/article/2691790aa8bb4cee94fc335f9c0e34c9
Autor:
Terra G. Arnason, Valerie MacDonald-Dickinson, Matthew Casey Gaunt, Gerald F. Davies, Liubov Lobanova, Brett Trost, Zoe E. Gillespie, Matthew Waldner, Paige Baldwin, Devon Borrowman, Hailey Marwood, Frederick S. Vizeacoumar, Franco J. Vizeacoumar, Christopher H. Eskiw, Anthony Kusalik, Troy A. A. Harkness
Publikováno v:
Cancers; Volume 14; Issue 17; Pages: 4215
Like humans, canine lymphomas are treated by chemotherapy cocktails and frequently develop multiple drug resistance (MDR). Their shortened clinical timelines and tumor accessibility make canines excellent models to study MDR mechanisms. Insulin-sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d390a401383bbe494927d366c9c46bf
Autor:
Carla Almendáriz-Palacios, Zoe E. Gillespie, Matthew Janzen, Valeria Martinez, Joanna M. Bridger, Tray A. A. Harkness, Darrell D. Mousseau, Christopher H. Eskiw
Publikováno v:
Advances in Medical Biochemistry, Genomics, Physiology, and Pathology ISBN: 9781003180449
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b526925bee079ce4eee0b72d806b3b9f
https://doi.org/10.1201/9781003180449-10
https://doi.org/10.1201/9781003180449-10
Phenolic extracts from five Saskatoon, Saskatchewan, bred and grown haskap berry varieties (Aurora, Blizzard, Honey Bee, Indigo Gem, and Tundra) were characterized via liquid chromatography with photodiode array detection (HPLC-PDA) and mass spectrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eac05c6c2cebef45d106b8c3f7b9c92
https://doi.org/10.1101/2021.08.04.455127
https://doi.org/10.1101/2021.08.04.455127