Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Christopher H. Dalton"'
Autor:
St John, Ronald Bruce
Publikováno v:
International Affairs (Royal Institute of International Affairs 1944-), 2014 Sep 01. 90(5), 1234-1236.
Externí odkaz:
http://www.jstor.org/stable/24538646
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 72
Carfentanil is a synthetic opioid restricted to veterinary use due to its potency. Public health concerns have been raised as to the potential of carfentanil to exhibit toxicity after absorption via the percutaneous route following unintentional cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b302ad66565ca4d95dc4f22023bb4d3a
https://pubmed.ncbi.nlm.nih.gov/33493622
https://pubmed.ncbi.nlm.nih.gov/33493622
Publikováno v:
Toxicology in Vitro. 53:121-125
The in vitro percutaneous penetration of the nerve agent VX through pig skin was measured in the absence and presence of water or artificial sweat to determine the impact such conditions might have on penetration rates. Experiments were performed wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa5fc9ab054c89eb680b724d6f4dd77
https://doi.org/10.1016/j.tiv.2018.08.003
https://doi.org/10.1016/j.tiv.2018.08.003
Autor:
John S. Graham, Robert P. Chilcott, J. Kevin Chipman, Hazem Matar, Christopher H. Dalton, Charlotte A. Hall, Helen L. Lydon
Publikováno v:
Journal of Applied Toxicology. 38:318-328
This study used a damaged skin, porcine model to evaluate the in vivo efficacy of WoundStat™ for the decontamination of superficial, nerve agent-contaminated wounds. Anaesthetized animals were randomly assigned to either control (n = 7), no deconta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcb08383e7d621a13b6c186518dfae8
https://doi.org/10.1002/jat.3542
https://doi.org/10.1002/jat.3542
Autor:
Charlotte A. Hall, J. Kevin Chipman, Christopher H. Dalton, John S. Graham, Robert P. Chilcott, Helen L. Lydon
Publikováno v:
Journal of Applied Toxicology. 37:1036-1045
This is the peer reviewed version of the following article: Charlotte A. Hall, et al, 'The percutaneous toxicokinetics of Sulphur mustard in a damaged skin porcine model and the evaluation of WoundStat™ as a topical decontaminant', Journal of Appli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e746220be396e23f7924e6a350fce797
https://doi.org/10.1002/jat.3453
https://doi.org/10.1002/jat.3453
Autor:
J. Kevin Chipman, Christopher H. Dalton, Charlotte A. Hall, Helen L. Lydon, John S. Graham, Robert P. Chilcott
Publikováno v:
Journal of Applied Toxicology. 37:976-984
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be3bbfac08eb3469527f56e309b0731a
https://doi.org/10.1002/jat.3446
https://doi.org/10.1002/jat.3446
Publikováno v:
Computational Toxicology. 17:100137
A simple compartmental mathematical model has been used to describe the penetration of VX, a relatively non-volatile, persistent organophosphorus nerve agent, through pig and guinea pig skin in vitro. Rate constants were derived by fitting the mathem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::735c9a82c24157bfa76170453ec72ba8
https://doi.org/10.1016/j.comtox.2020.100137
https://doi.org/10.1016/j.comtox.2020.100137
Publikováno v:
Toxicology in Vitro. 30:454-461
Diffusion cells are used to determine the penetration of chemicals through skin in vitro. The cells have a limited surface area defined by the edge of the donor chamber. Should the penetrant spread rapidly to this containment limit the penetration ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d941415d0e3d1177cbe012bb28ed418
https://doi.org/10.1016/j.tiv.2015.09.016
https://doi.org/10.1016/j.tiv.2015.09.016
Autor:
Charlotte A. Hall, Helen L. Lydon, J. Kevin Chipman, John Jenner, Christopher H. Dalton, John S. Graham, Robert P. Chilcott
Publikováno v:
Cutaneous and ocular toxicology. 37(2)
Purpose: The aim of this study was to evaluate a candidate haemostat (WoundStat™), down-selected from previous in vitro studies, for efficacy as a potential skin decontaminant against the chemical warfare agent pinacoyl methylfluorophosphonate (Som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407b5d1d01d74663bcafb358a672796b
https://pubmed.ncbi.nlm.nih.gov/28853336
https://pubmed.ncbi.nlm.nih.gov/28853336
Autor:
John S. Graham, Charlotte A. Hall, Robert P. Chilcott, Christopher H. Dalton, Helen L. Lydon, James K. Chipman, John Jenner
Publikováno v:
Journal of Applied Toxicology. 35:543-550
Previous studies have demonstrated that haemostatic products with an absorptive mechanism of action retain their clotting efficiency in the presence of toxic materials and are effective in decontaminating chemical warfare (CW) agents when applied to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c68f3e5dee44da50bb4610e581bf5dbc
https://doi.org/10.1002/jat.3060
https://doi.org/10.1002/jat.3060