Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Christopher H. Chay"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 4, Iss 3, Pp 191-194 (2002)
Integrin αvβ3 is involved in varied cell biological activities, including angiogenesis, cell adhesion, and migration on several extracellular matrix components. Although αvβ3 is not typically expressed in epithelial cells, it is expressed in macr
Externí odkaz:
https://doaj.org/article/dd78d19342e1455089e4b28b778002cd
Autor:
Yucai Wang, Chan Yoon Cheah, Elisabeth Vandenberghe, Mitul Gandhi, Nirav N. Shah, Martin Dreyling, Toby A. Eyre, Ming Yin, Minna Balbas, Christopher H. Chay, Jeff P. Sharman, Michael L. Wang, Jennifer Kherani, Wojciech Jurczak, Steven Le Gouill, David Andorsky
Publikováno v:
Blood. 138:2422-2422
Background: Covalent Bruton's Tyrosine Kinase (BTK) inhibitors (BTKi) have transformed the management of relapsed mantle cell lymphoma (MCL), but these treatments are not curative and the majority of patients will require additional treatment. Covale
Autor:
Hyung-Lae Lee, James D. Gendernalik, Carlton R. Cooper, Evan T. Keller, Kenneth J. Pienta, Christopher H. Chay, Laurie K. McCauley, Russell S. Taichman, Jasmine Bhatia
Publikováno v:
Cancer. 97:739-747
BACKGROUND Prostate carcinoma (PC) frequently metastasizes to bone, where it causes significant morbidity and mortality. Stromal elements in the primary and metastatic target organs are important mediators of tumor cell intravasation, chemoattraction
Publikováno v:
Expert Opinion on Therapeutic Targets. 6:123-127
Androgen independence and bone metastasis are lethal complications in patients with advanced prostate cancer. Presently, there is no cure for patients with androgen-independent prostate cancer. In order to develop more effective therapies for this di
Autor:
Kenneth J. Pienta, Christopher H. Chay
Publikováno v:
Journal of Cellular Biochemistry. 79:123-129
Autor:
William B. Coleman, William E. Bakewell, James L. Mohler, Gary J. Smith, Scott M. Silver, Christopher H. Chay, Yousuf Sharief
Publikováno v:
Clinical & Experimental Metastasis. 13:474-480
The more differentiated components of a primary tumor may produce substances that reduce the growth rate and metastatic potential of more aggressive components. In the Dunning R-3327 prostatic adenocarcinoma model, cancer cell motility is required fo
Autor:
Anne Broadwater, Amy L. Rubinstein, David G. Klapper, Patricia A. Bedinger, Christopher H. Chay
Publikováno v:
Gene. 131:227-230
Sequence analysis of a pollen-specific cDNA from maize has identified a homolog ( Zea mI ) of the gene ( Lol pI ) encoding the major allergen of rye-grass pollen. The protein encoded by the partial cDNA sequence is 59.3% identical and 72.7% similar t
Autor:
Judith M. Thorn, Patricia A. Bedinger, Erich G. Buehler, Thomas M. Whelan, Christopher H. Chay
Publikováno v:
Plant Physiology. 100:756-761
Zea mays (maize) pollen exines have been purified with the use of differential centrifugation and sucrose gradients, followed by mild detergent and high salt treatment. The final exine fraction is highly purified from other organelles and subcellular
Publikováno v:
Clinical prostate cancer. 1(1)
Despite the benefits of local therapy with radical prostatectomy and radiation, many patients with prostate cancer require hormonal ablation. While chemotherapy has proven efficacy when the disease progresses to androgen-independent prostate cancer,
Autor:
Alvin H. Schmaier, James D. Gendernalik, Arul M. Chinnaiyan, Saravana M. Dhanasekaran, Christopher H. Chay, Carlton R. Cooper, Kenneth J. Pienta, Mark A. Rubin
Publikováno v:
Urology. 60(5)
Objectives To identify genes important in prostate cancer metastatic to bone. Bone-specific metastasis is a common feature of prostate cancer and a significant cause of morbidity. Methods To identify factors involved in organ-specific metastasis, we