Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christopher H. Arehart"'
Autor:
Christopher H. Arehart, John D. Sterrett, Rosanna L. Garris, Ruth E. Quispe-Pilco, Christopher R. Gignoux, Luke M. Evans, Maggie A. Stanislawski
Publikováno v:
mSystems, Vol 9, Iss 1 (2024)
ABSTRACTInflammatory bowel disease (IBD) is characterized by complex etiology and a disrupted colonic ecosystem. We provide a framework for the analysis of multi-omic data, which we apply to study the gut ecosystem in IBD. Specifically, we train and
Externí odkaz:
https://doaj.org/article/25f4da1db4b34af2973aca4ff183f560
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract The Morbidity and Mortality Weekly Reports of the U.S. Centers for Disease Control and Prevention document a raw proxy for counts of pertussis cases in the U.S., and the Project Tycho (PT) database provides an improved source of these weekly
Externí odkaz:
https://doaj.org/article/ac71f77eff1e46e79590225b15d94306
Autor:
Christopher H. Arehart, John D. Sterrett, Rosanna L. Garris, Ruth E. Quispe-Pilco, Christopher R. Gignoux, Luke M. Evans, Maggie A. Stanislawski
Inflammatory Bowel Disease (IBD) is characterized by complex etiology and a disrupted gut microbiota. The substantial non-genetic variance for Crohn’s disease and ulcerative colitis (≥25%) suggests that both genetic and environmental factors cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f78f0bffc64ac2526bec82e8c255d65
https://doi.org/10.1101/2022.09.14.508056
https://doi.org/10.1101/2022.09.14.508056
Autor:
Luke M. Evans, Christopher H. Arehart, Andrew D. Grotzinger, Travis J. Mize, Maizy S. Brasher, Jerry A. Stitzel, Marissa A. Ehringer, Charles A. Hoeffer
It remains unknown to what extent gene-gene interactions contribute to complex traits. Here, we introduce a new approach using predicted gene expression to perform exhaustive transcriptome-wide interaction studies (TWISs) for multiple traits across a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::588d6940f3afc22727ff4d0e65e3f3f2
https://doi.org/10.1101/2022.08.16.504187
https://doi.org/10.1101/2022.08.16.504187
Autor:
Luke M. Evans, Christopher H. Arehart, Andrew D. Grotzinger, Travis J. Mize, Maizy S. Brasher, Jerry A. Stitzel, Marissa A. Ehringer, Charles A. Hoeffer
Publikováno v:
PLOS Genetics. 19:e1010693
It remains unknown to what extent gene-gene interactions contribute to complex traits. Here, we introduce a new approach using predicted gene expression to perform exhaustive transcriptome-wide interaction studies (TWISs) for multiple traits across a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d5cc492f6dd9d5374ad35baedefd994
https://doi.org/10.1371/journal.pgen.1010693
https://doi.org/10.1371/journal.pgen.1010693
Autor:
Lynda C. Schneider, Richard L. Gallo, Kathleen C. Barnes, Jon M. Hanifin, Sameer Chavan, Christopher H. Arehart, Emma Guttman-Yassky, Mark K. Slifka, Rasika A. Mathias, Jonathan M. Spergel, Donald Y.M. Leung, Michelle Daya, Gloria David, Amy S. Paller, Monica Campbell, Christopher R. Gignoux, Lisa A. Beck, Meher Preethi Boorgula, Peck Y. Ong, Tissa Hata, Nicholas M. Rafaels
Publikováno v:
J Allergy Clin Immunol
The Journal of allergy and clinical immunology, vol 149, iss 1
The Journal of allergy and clinical immunology, vol 149, iss 1
BACKGROUND: While numerous genetic loci associated with atopic dermatitis (AD) have been discovered, to date, work leveraging the combined burden of AD risk variants across the genome to predict disease risk has been limited. OBJECTIVES: This study a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e50c197cada719b9fa4de296caf81f1
https://pubmed.ncbi.nlm.nih.gov/34111454
https://pubmed.ncbi.nlm.nih.gov/34111454
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
The Morbidity and Mortality Weekly Reports of the U.S. Centers for Disease Control and Prevention document a raw proxy for counts of pertussis cases in the U.S., and the Project Tycho (PT) database provides an improved source of these weekly data. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d52921d9439d095e086f7bd3bf9169
https://pubmed.ncbi.nlm.nih.gov/31875051
https://pubmed.ncbi.nlm.nih.gov/31875051
Autor:
Adolfo Correa, Annie Green Howard, Kari E North, Jerome I Rotter, Stephen S Rich, Ulrike Peters, Zhe Wang, Michael Y Tsai, Penny Gordon-Larsen, Christie Ballantyne, Shia T Kent, Ruth J F Loos, Christy L Avery, Xiuqing Guo, Jie Yao, Yao Hu, Mariaelisa Graff, Paul S de Vries, Keri L Monda, Moa P Lee, Sofia F Dimos, Laura M Raffield, Anna F Ballou, Carolina G Downie, Christopher H Arehart, Zhaohui Du, Christopher R Gignoux, Jeffrey Haessler, Helina Kassahun, J Antonio G Lopez, Michael H Preuss, Shannon L Rhodes, Rina Yarosh, Charles L Kooperberg
Publikováno v:
Open Heart, Vol 10, Iss 2 (2023)
Introduction The independent and causal cardiovascular disease risk factor lipoprotein(a) (Lp(a)) is elevated in >1.5 billion individuals worldwide, but studies have prioritised European populations.Methods Here, we examined how ancestrally diverse s
Externí odkaz:
https://doaj.org/article/1a269fc98b7043cc85c2bdef81e77451