Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Christopher H Stuart"'
Autor:
Christopher H Stuart, Kathryn R Riley, Olcay Boyacioglu, Denise M Herpai, Waldemar Debinski, Shadi Qasem, Frank C Marini, Christa L. Colyer, William H Gmeiner
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Breast cancer (BC) results in ≃40,000 deaths each year in the United States and even among survivors treatment of the disease may have devastating consequences, including increased risk for heart disease and cognitive impairment resulting from the
Externí odkaz:
https://doaj.org/article/c5d25eb2e8074b42a30c604653f5bab8
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Treatment with doxorubicin (Dox) results in serious systemic toxicities that limit effectiveness for cancer treatment and cause long-term health issues for cancer patients. We identified a new DNA aptamer to prostate-specific membrane antigen (PSMA)
Externí odkaz:
https://doaj.org/article/7d9b257cd5734385a7b8d4bd3d11c1f0
Autor:
Joshua Yoho, Christopher H. Stuart, Jessica Palmer, Kevin Wogensthal, Shawn Swavey, Madhuri Kango-Singh, Kristen K. Comfort, Thomas L. Bennett, William H. Gmeiner
Publikováno v:
European Journal of Inorganic Chemistry. 2017:153-159
A new water-soluble zinc(II) porphyrin has been synthesized and characterized by high resolution mass spectroscopy, elemental analysis, and electronic absorption spectroscopy. The zinc(II) porphyrin (ZnPor) is designed with three N-methylated pyridyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99395dd8181b5d180ace8c670ac74c1d
https://doi.org/10.1002/ejic.201601077
https://doi.org/10.1002/ejic.201601077
Publikováno v:
Leukemia Research. 39:229-235
The polymeric fluoropyrimidine F10 displays excellent anti-leukemia activity in pre-clinical models of acute myelogenous leukemia (AML) through dual targeting of thymidylate synthase and DNA topoisomerase 1. Here we report that F10 activates the extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b722c8fac3872fe8105865e9d18310
https://doi.org/10.1016/j.leukres.2014.11.006
https://doi.org/10.1016/j.leukres.2014.11.006
Publikováno v:
The Prostate. 75:360-369
Background Intracellular Zn(2+) levels decrease during prostate cancer progression and agents that modulate intracellular Zn(2+) are cytotoxic to prostate cancer cells by an incompletely described mechanism. F10 is a new polymeric fluoropyrimidine dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcb7e99af3f1e90911705bd9c6fc5422
https://doi.org/10.1002/pros.22922
https://doi.org/10.1002/pros.22922
Autor:
Christopher H. Stuart, David A. Horita, Michael J. Thomas, Freddie R. Salsbury, Mark O. Lively, William H. Gmeiner
Publikováno v:
Bioconjugate Chemistry
Doxorubicin (Dox) is widely used for breast cancer treatment but causes serious side- effects including cardiotoxicity that may adversely impact patient lifespan even if treatment is successful. The present invention relates to selective conjugation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09fe215df77270e8221e32bccd3eaae6
https://doi.org/10.1021/bc4005427
https://doi.org/10.1021/bc4005427
Autor:
Ravi Singh, K.C. Balaji, William H. Gmeiner, Thomas L. Smith, Christopher H. Stuart, David L. Caudell, Ralph B. D'Agostino
Publikováno v:
Nanomedicine (London, England). 11(10)
Aim: To evaluate the potential use of zinc chelation for prostate cancer therapy using a new liposomal formulation of the zinc chelator, N,N,N’,N’-tetrakis(2-pyridylmethyl)-ethylenediamine (TPEN). Materials & methods: TPEN was encapsulated in non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de5208b529e438888c749717690682b6
https://pubmed.ncbi.nlm.nih.gov/27077564
https://pubmed.ncbi.nlm.nih.gov/27077564
Autor:
Denise Herpai, Olcay Boyacioglu, Christopher H. Stuart, Christa L. Colyer, Shadi Qasem, Waldemar Debinski, Kathryn R. Riley, William H. Gmeiner, Frank C. Marini
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Breast cancer (BC) results in similar to 40,000 deaths each year in the United States and even among survivors treatment of the disease may have devastating consequences, including increased risk for heart disease and cognitive impairment resulting f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e26dc8d1689d79ab3a2ec104e528a2
Autor:
William H, Gmeiner, Olcay, Boyacioglu, Christopher H, Stuart, Jamie, Jennings-Gee, K C, Balaji
Publikováno v:
The Prostate. 75(4)
Intracellular Zn(2+) levels decrease during prostate cancer progression and agents that modulate intracellular Zn(2+) are cytotoxic to prostate cancer cells by an incompletely described mechanism. F10 is a new polymeric fluoropyrimidine drug-candidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f0d7bb099849c7f26e3b5cee45c7b10
https://pubmed.ncbi.nlm.nih.gov/25408502
https://pubmed.ncbi.nlm.nih.gov/25408502
Autor:
James Ross, Christopher H. Stuart, Michael B. Morgan, Kylia Goodner, Elizabeth Stepp, Angela Z. Poole, Ernesto Weil, Cydney Wilbanks
Publikováno v:
PeerJ, Vol 3, p e1371 (2015)
PeerJ
PeerJ
Molecular stress responses associated with coral diseases represent an under-studied area of cnidarian transcriptome investigations. Caribbean Yellow Band Disease (CYBD) is considered a disease ofSymbiodiniumwithin the tissues of the coral hostOrbice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b6eecee66859128c82fba6b974ab24
https://doi.org/10.7717/peerj.1371
https://doi.org/10.7717/peerj.1371