Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christopher H S McIntosh"'
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32675 (2012)
In response to a meal, Glucose-dependent Insulinotropic Polypeptide (GIP) and Glucagon-like Peptide-1 (GLP-1) are released from gut endocrine cells into the circulation and interact with their cognate G-protein coupled receptors (GPCRs). Receptor act
Externí odkaz:
https://doaj.org/article/d40fd39295c244c7ba26f30a92dd57a3
Autor:
Su-Jin Kim, Cuilan Nian, Subashini Karunakaran, Susanne M Clee, Carlos M Isales, Christopher H S McIntosh
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40156 (2012)
Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone that potentiates glucose-stimulated insulin secretion during a meal. Since GIP has also been shown to exert β-cell prosurvival and adipocyte lipogenic effects in rodent
Externí odkaz:
https://doaj.org/article/d81c14c65d904b4e959668416981da14
Autor:
Scott B Widenmaier, Su-Jin Kim, Gary K Yang, Thomas De Los Reyes, Cuilan Nian, Ali Asadi, Yutaka Seino, Timothy J Kieffer, Yin Nam Kwok, Christopher H S McIntosh
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9590 (2010)
AIMS:The gastrointestinal hormone GIP promotes pancreatic islet function and exerts pro-survival actions on cultured beta-cells. However, GIP also promotes lipogenesis, thus potentially restricting its therapeutic use. The current studies evaluated t
Externí odkaz:
https://doaj.org/article/6229a1c612d84bfea4a9e239367cca18
Publikováno v:
Experimental Models of Diabetes ISBN: 9780203756386
Experimental Models of Diabetes
Experimental Models of Diabetes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2800587a13c8f0f9820c7afb5401597a
https://doi.org/10.1201/9780203756386-14
https://doi.org/10.1201/9780203756386-14
Control of Gastric Acid Secretion and the Endocrine Pancreas by Gastrointestinal Regulatory Peptides
Autor:
Christopher H. S. Mcintosh
Publikováno v:
American Zoologist. 35:455-465
Synopsis. Gastrointestinal peptides that perform the dual functions of regulating gastric acid secretion and secretion by the endocrine pancreas are reviewed. The regulation of release of gastrin and gastrin releasing peptide and their roles in stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35993a295570e9f6b3e2fba033df1a96
https://doi.org/10.1093/icb/35.6.455
https://doi.org/10.1093/icb/35.6.455
Publikováno v:
Vitamins and hormones. 84
The insulin secretory response to a meal results largely from glucose stimulation of the pancreatic islets and both direct and indirect (autonomic) glucose-dependent stimulation by incretin hormones released from the gastrointestinal tract. Two incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fb5a87ed6bb1d1c03cf07d4c7f9e34e
https://pubmed.ncbi.nlm.nih.gov/21094896
https://pubmed.ncbi.nlm.nih.gov/21094896
Publikováno v:
Vitamins and hormones. 80
Glucose-dependent insulinotropic polypeptide (GIP; gastric inhibitory polypeptide) is a 42 amino acid hormone that is produced by enteroendocrine K-cells and released into the circulation in response to nutrient stimulation. Both GIP and glucagon-lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2503fea8543c51b46f8d1261ea76e01b
https://pubmed.ncbi.nlm.nih.gov/19251046
https://pubmed.ncbi.nlm.nih.gov/19251046
Publikováno v:
The Journal of biological chemistry. 282(12)
Glucose-dependent insulinotropic polypeptide (GIP) has been mainly studied because of its glucose-dependent insulinotropic action and its ability to regulate beta-cell proliferation and survival. Considerably less is known about the effects of GIP on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63612af7ad3c47781b73b89f08fe23df
https://pubmed.ncbi.nlm.nih.gov/17244606
https://pubmed.ncbi.nlm.nih.gov/17244606
Publikováno v:
Advances in experimental medicine and biology. 575
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1ea6097baa916887f2533e4a5b59a5a
https://pubmed.ncbi.nlm.nih.gov/16700515
https://pubmed.ncbi.nlm.nih.gov/16700515
Autor:
Su-Jin, Kim, Woo Sung, Choi, John Song Mou, Han, Garth, Warnock, David, Fedida, Christopher H S, McIntosh
Publikováno v:
The Journal of biological chemistry. 280(31)
The mechanisms involved in glucose regulation of insulin secretion by ATP-sensitive (K(ATP)) and calcium-activated (K(CA)) potassium channels have been extensively studied, but less is known about the role of voltage-gated (K(V)) potassium channels i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::584ef48c0c419cdfff699700db2c9835
https://pubmed.ncbi.nlm.nih.gov/15955806
https://pubmed.ncbi.nlm.nih.gov/15955806