Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Christopher Gwenin"'
Autor:
Carol Jones, Christopher Gwenin
Publikováno v:
Physiological Reports, Vol 8, Iss 24, Pp n/a-n/a (2021)
Abstract This review examines the stress hormone cortisol which plays an important role in regulating and supporting different bodily functions. Disruption in cortisol production has an impact on health and this review looks at a wide range of papers
Externí odkaz:
https://doaj.org/article/44ae0bdeb1824b448c4cedcc7424008f
Publikováno v:
MicrobiologyOpen, Vol 9, Iss 10, Pp n/a-n/a (2020)
Abstract Directed enzyme prodrug therapy (DEPT) is a cancer chemotherapy strategy in which bacterial enzymes are delivered to a cancer site before prodrug administration, resulting in prodrug activation at the cancer site and more localized treatment
Externí odkaz:
https://doaj.org/article/c861a008e39e4900ad9cd58acd6875f8
Autor:
Patrick Ball, Robert Hobbs, Simon Anderson, Emma Thompson, Vanessa Gwenin, Christopher Von Ruhland, Christopher Gwenin
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 517 (2021)
The bacterial nitroreductase NfnB has been the focus of a great deal of research for its use in directed enzyme prodrug therapy in combination with the nitroreductase prodrug CB1954 with this combination of enzyme and prodrug even entering clinical t
Externí odkaz:
https://doaj.org/article/24a62a4fe0ae4f908ea6f8377f2c0041
Publikováno v:
Sensors, Vol 21, Iss 7, p 2319 (2021)
The pH drop in the hindgut of the horse is caused by lactic acid-producing bacteria which are abundant when a horse’s feeding regime is excessively carbohydrate rich. This drop in pH below six causes hindgut acidosis and may lead to laminitis. Lact
Externí odkaz:
https://doaj.org/article/aa76ab2eee184a5b934b476008f49896
Autor:
Alice Jane Heeroma, Christopher Gwenin
Publikováno v:
Sensors, Vol 20, Iss 15, p 4182 (2020)
Population extended life expectancy has significantly increased the risk of septic shock in an ageing population. Sepsis affects roughly 20 million people every year, resulting in over 11 million deaths. The need for faster more accurate diagnostics
Externí odkaz:
https://doaj.org/article/74b2dda762a646fa85337fc05077cabe
Publikováno v:
Toxins, Vol 7, Iss 5, Pp 1544-1555 (2015)
Botulinum neurotoxin is one of the deadliest biological toxins known to mankind and is able to cause the debilitating disease botulism. The rapid detection of the different serotypes of botulinum neurotoxin is essential for both diagnosis of botulism
Externí odkaz:
https://doaj.org/article/729f4c80c2a04853a61ec01c45709b9a
Publikováno v:
Sensing and Bio-Sensing Research, Vol 2, Iss C, Pp 12-15 (2014)
The standard method for the detection of botulinum neurotoxin is currently the mouse bioassay which is considered to be the most reliable method for the detection of the active form of this toxin. Despite this it is a time-consuming and expensive ass
Externí odkaz:
https://doaj.org/article/e3f21f039d1a486e9397ba966e81d98e
Autor:
A. Prysor Williams, James Gibbons, Mark S. Baird, Juma'a R. Al Dulayymi, Alison Jones, Christopher Gwenin, Samuel Fitch, Carys Davies
Publikováno v:
RSC Med Chem
Background: mycobacterial cells contain complex mixtures of mycolic acid esters. These can be used as antigens recognised by antibodies in the serum of individuals with active tuberculosis, caused by Mycobacterium tuberculosis. In high burden populat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f0f9317379a622c6ff2db30597d754
https://doi.org/10.1039/d0md00325e
https://doi.org/10.1039/d0md00325e
Autor:
Christopher Gwenin, Jennifer Halliwell
Publikováno v:
Toxins, Vol 5, Iss 8, Pp 1381-1391 (2013)
Botulinum neurotoxins are one of the most potent toxins known to man. Current methods of detection involve the quantification of the toxin but do not take into account the percentage of the toxin that is active. At present the assay used for monitori
Externí odkaz:
https://doaj.org/article/04a3fb2da9c44c8abf9040704b01b1a4
Autor:
Bazilah Awang Abd Manaf, Shyang Pei Hong, Mohammad Rizwan, Fareeha Arshad, Christopher Gwenin, Minhaz Uddin Ahmed
Publikováno v:
Surfaces and Interfaces. 36:102596
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5657fcd9f3e593f56d565092b8158fde
https://doi.org/10.1016/j.surfin.2022.102596
https://doi.org/10.1016/j.surfin.2022.102596